CX295720

BLAST of CX295720 vs. ExPASy Swiss-Prot
Match: RAF1_RAT (RAF proto-oncogene serine/threonine-protein kinase OS=Rattus norvegicus GN=Raf1 PE=1 SV=1)

HSP 1 Score: 56.6102 bits (135), Expect = 9.817e-11
Identity = 31/99 (31.31%), Postives = 53/99 (53.54%), Query Frame = 2

Query:   71 FRAELKVLTHVHHLNLVRLIGYCFEGSLCVVYEFIENGNLSQHLRGSGRDPLAWSTRLQIALDSARGLEYIHEHTVPVYIHRDIKSANILIDKNFRAKI 367
            FR E+ VL    H+N++  +GY  + +L +V ++ E  +L +HL             + IA  +A+G++Y+H   +   IHRD+KS NI + +    KI
Sbjct:  390 FRNEVAVLRKTRHVNILLFMGYMTKDNLAIVTQWCEGSSLYKHLHVQ-ETKFQMFQLIDIARQTAQGMDYLHAKNI---IHRDMKSNNIFLHEGLTVKI 484          

HSP 2 Score: 30.4166 bits (67), Expect = 9.817e-11
Identity = 17/60 (28.33%), Postives = 32/60 (53.33%), Query Frame = 1

Query:  364 DFGLTKLTEFGNASFYTSGLQGTFGYFPPEAV----SGNVSPKTDVFAFGVVLYELISAK 531
            DFGL  +    + S       G+  +  PE +    +   S ++DV+++G+VLYEL++ +
Sbjct:  486 DFGLATVKSRWSGSQQVEQPTGSVLWMAPEVIRMQDNNPFSFQSDVYSYGIVLYELMTGE 545          

BLAST of CX295720 vs. ExPASy Swiss-Prot
Match: RAF1_PONAB (RAF proto-oncogene serine/threonine-protein kinase OS=Pongo abelii GN=RAF1 PE=2 SV=1)

HSP 1 Score: 56.6102 bits (135), Expect = 9.817e-11
Identity = 31/99 (31.31%), Postives = 53/99 (53.54%), Query Frame = 2

Query:   71 FRAELKVLTHVHHLNLVRLIGYCFEGSLCVVYEFIENGNLSQHLRGSGRDPLAWSTRLQIALDSARGLEYIHEHTVPVYIHRDIKSANILIDKNFRAKI 367
            FR E+ VL    H+N++  +GY  + +L +V ++ E  +L +HL             + IA  +A+G++Y+H   +   IHRD+KS NI + +    KI
Sbjct:  390 FRNEVAVLRKTRHVNILLFMGYMTKDNLAIVTQWCEGSSLYKHLHVQ-ETKFQMFQLIDIARQTAQGMDYLHAKNI---IHRDMKSNNIFLHEGLTVKI 484          

HSP 2 Score: 30.4166 bits (67), Expect = 9.817e-11
Identity = 17/60 (28.33%), Postives = 32/60 (53.33%), Query Frame = 1

Query:  364 DFGLTKLTEFGNASFYTSGLQGTFGYFPPEAV----SGNVSPKTDVFAFGVVLYELISAK 531
            DFGL  +    + S       G+  +  PE +    +   S ++DV+++G+VLYEL++ +
Sbjct:  486 DFGLATVKSRWSGSQQVEQPTGSVLWMAPEVIRMQDNNPFSFQSDVYSYGIVLYELMTGE 545          

BLAST of CX295720 vs. ExPASy Swiss-Prot
Match: RAF1_HUMAN (RAF proto-oncogene serine/threonine-protein kinase OS=Homo sapiens GN=RAF1 PE=1 SV=1)

HSP 1 Score: 56.6102 bits (135), Expect = 9.817e-11
Identity = 31/99 (31.31%), Postives = 53/99 (53.54%), Query Frame = 2

Query:   71 FRAELKVLTHVHHLNLVRLIGYCFEGSLCVVYEFIENGNLSQHLRGSGRDPLAWSTRLQIALDSARGLEYIHEHTVPVYIHRDIKSANILIDKNFRAKI 367
            FR E+ VL    H+N++  +GY  + +L +V ++ E  +L +HL             + IA  +A+G++Y+H   +   IHRD+KS NI + +    KI
Sbjct:  390 FRNEVAVLRKTRHVNILLFMGYMTKDNLAIVTQWCEGSSLYKHLHVQ-ETKFQMFQLIDIARQTAQGMDYLHAKNI---IHRDMKSNNIFLHEGLTVKI 484          

HSP 2 Score: 30.4166 bits (67), Expect = 9.817e-11
Identity = 17/60 (28.33%), Postives = 32/60 (53.33%), Query Frame = 1

Query:  364 DFGLTKLTEFGNASFYTSGLQGTFGYFPPEAV----SGNVSPKTDVFAFGVVLYELISAK 531
            DFGL  +    + S       G+  +  PE +    +   S ++DV+++G+VLYEL++ +
Sbjct:  486 DFGLATVKSRWSGSQQVEQPTGSVLWMAPEVIRMQDNNPFSFQSDVYSYGIVLYELMTGE 545          

BLAST of CX295720 vs. ExPASy Swiss-Prot
Match: KINY_DICDI (Probable serine/threonine-protein kinase kinY OS=Dictyostelium discoideum GN=kinY PE=2 SV=1)

HSP 1 Score: 56.225 bits (134), Expect = 9.849e-11
Identity = 39/124 (31.45%), Postives = 63/124 (50.81%), Query Frame = 2

Query:   35 AIKKMDMQAS------KEFRAELKVLTHVHHLNLVRLIGYCFE--------------GSLCVVYEFIENGNLSQHLRGSGRDPLAWSTRLQIALDSARGLEYIHEHTVPVYIHRDIKSANILID 346
            AIKK+  + S      K  + E+ VL ++ H N+V+ IG  +E               S  +V E+I  GNL + ++ + +D      R++++LD A  + Y+H   +   I RD+KS NILID
Sbjct:   57 AIKKIQNEKSEKNEFIKYLKREVAVLKNIQHPNIVQFIGVYYEPLASPSLVNRLLNSSSTWIVTEYIGGGNLHERIKDTKKD-FPIELRIKLSLDIALAMAYLHSRDI---IFRDLKSKNILID 176          

HSP 2 Score: 30.8018 bits (68), Expect = 9.849e-11
Identity = 18/58 (31.03%), Postives = 26/58 (44.83%), Query Frame = 1

Query:  364 DFGLTKLTEFGNASFYTSGLQGTFGYFPPEAVSG-NVSPKTDVFAFGVVLYELISAKQ 534
            DFG  ++            + GT     PE + G       D+F+FGVVL E+I  K+
Sbjct:  188 DFGFARILNKKQQGNRHLSICGTDSIMAPELILGMEYDESVDIFSFGVVLLEMILRKK 245          

BLAST of CX295720 vs. ExPASy Swiss-Prot
Match: AVR2B_MOUSE (Activin receptor type-2B OS=Mus musculus GN=Acvr2b PE=1 SV=1)

HSP 1 Score: 47.7506 bits (112), Expect = 9.871e-11
Identity = 33/124 (26.61%), Postives = 61/124 (49.19%), Query Frame = 2

Query:   35 AIKKMDMQASKEFRAELKVLTH--VHHLNLVRLI-----GYCFEGSLCVVYEFIENGNLSQHLRGSGRDPLAWSTRLQIALDSARGLEYIHEHT--------VPVYIHRDIKSANILIDKNFRA 361
            A+K   +Q  + +++E ++ +   + H NL++ I     G   E  L ++  F + G+L+ +L+G+    + W+    +A   +RGL Y+HE           P   HRD KS N+L+  +  A
Sbjct:  239 AVKIFPLQDKQSWQSEREIFSTPGMKHENLLQFIAAEKRGSNLEVELWLITAFHDKGSLTDYLKGN---IITWNELCHVAETMSRGLSYLHEDVPWCRGEGHKPSIAHRDFKSKNVLLKSDLTA 359          

HSP 2 Score: 39.2762 bits (90), Expect = 9.871e-11
Identity = 38/130 (29.23%), Postives = 57/130 (43.85%), Query Frame = 1

Query:  364 DFGLTKLTEFGNASFYTSGLQGTFGYFPPEAVSGNVS------PKTDVFAFGVVLYELISAKQA--------IVTTNETITQSKGLVALFEEVLRQPAPRENLHKLVDPRLGDNYPLDSVIKMAQLARAC 711
            DFGL    E G     T G  GT  Y  PE + G ++       + D++A G+VL+EL+S  +A        ++   E I Q   L  L E V         +HK + P + D++     +K   LA+ C
Sbjct:  363 DFGLAVRFEPGKPPGDTHGQVGTRRYMAPEVLEGAINFQRDAFLRIDMYAMGLVLWELVSRCKAADGPVDEYMLPFEEEIGQHPSLEELQEVV---------VHKKMRPTIKDHW-----LKHPGLAQLC 478          

BLAST of CX295720 vs. ExPASy Swiss-Prot
Match: AVR2B_HUMAN (Activin receptor type-2B OS=Homo sapiens GN=ACVR2B PE=1 SV=3)

HSP 1 Score: 47.7506 bits (112), Expect = 9.885e-11
Identity = 33/124 (26.61%), Postives = 61/124 (49.19%), Query Frame = 2

Query:   35 AIKKMDMQASKEFRAELKVLTH--VHHLNLVRLI-----GYCFEGSLCVVYEFIENGNLSQHLRGSGRDPLAWSTRLQIALDSARGLEYIHEHT--------VPVYIHRDIKSANILIDKNFRA 361
            A+K   +Q  + +++E ++ +   + H NL++ I     G   E  L ++  F + G+L+ +L+G+    + W+    +A   +RGL Y+HE           P   HRD KS N+L+  +  A
Sbjct:  215 AVKIFPLQDKQSWQSEREIFSTPGMKHENLLQFIAAEKRGSNLEVELWLITAFHDKGSLTDYLKGN---IITWNELCHVAETMSRGLSYLHEDVPWCRGEGHKPSIAHRDFKSKNVLLKSDLTA 335          

HSP 2 Score: 39.2762 bits (90), Expect = 9.885e-11
Identity = 38/130 (29.23%), Postives = 57/130 (43.85%), Query Frame = 1

Query:  364 DFGLTKLTEFGNASFYTSGLQGTFGYFPPEAVSGNVS------PKTDVFAFGVVLYELISAKQA--------IVTTNETITQSKGLVALFEEVLRQPAPRENLHKLVDPRLGDNYPLDSVIKMAQLARAC 711
            DFGL    E G     T G  GT  Y  PE + G ++       + D++A G+VL+EL+S  +A        ++   E I Q   L  L E V         +HK + P + D++     +K   LA+ C
Sbjct:  339 DFGLAVRFEPGKPPGDTHGQVGTRRYMAPEVLEGAINFQRDAFLRIDMYAMGLVLWELVSRCKAADGPVDEYMLPFEEEIGQHPSLEELQEVV---------VHKKMRPTIKDHW-----LKHPGLAQLC 454          

BLAST of CX295720 vs. ExPASy Swiss-Prot
Match: AVR2A_XENLA (Activin receptor type-2A OS=Xenopus laevis GN=acvr2a PE=2 SV=1)

HSP 1 Score: 47.7506 bits (112), Expect = 9.885e-11
Identity = 37/128 (28.91%), Postives = 62/128 (48.44%), Query Frame = 2

Query:   26 QKAAIKKMDMQASKEFRAELKV--LTHVHHLNLVRLIGYCFEGS-----LCVVYEFIENGNLSQHLRGSGRDPLAWSTRLQIALDSARGLEYIHEHTV-------PVYIHRDIKSANILIDKNFRAKI 367
            +  A+K   +Q    ++ E ++  L  + H N++  IG    G+     L ++  F E G+L+ +L+ +    ++W+    IA   ARGL ++HE          P   HRDIKS N+L+  N  A I
Sbjct:  215 ETVAVKIFPVQDKLSWQNEYEIYSLPGMKHENILYFIGAEKRGTNLDTDLWLITAFHEKGSLTDYLKAN---VVSWNELCLIAETMARGLSHLHEDIPGLKDGHKPAVAHRDIKSKNVLLKNNLTACI 339          

HSP 2 Score: 39.2762 bits (90), Expect = 9.885e-11
Identity = 23/60 (38.33%), Postives = 33/60 (55.00%), Query Frame = 1

Query:  364 DFGLTKLTEFGNASFYTSGLQGTFGYFPPEAVSGNVS------PKTDVFAFGVVLYELIS 525
            DFGL    E G ++  T G  GT  Y  PE + G ++       + D++AFG+VL+EL S
Sbjct:  341 DFGLALKFEAGKSAGDTHGQVGTRRYMAPEVLEGAINFQRDAFLRIDMYAFGLVLWELAS 400          

BLAST of CX295720 vs. ExPASy Swiss-Prot
Match: FRK_RAT (Tyrosine-protein kinase FRK OS=Rattus norvegicus GN=Frk PE=1 SV=3)

HSP 1 Score: 50.447 bits (119), Expect = 9.889e-11
Identity = 23/96 (23.96%), Postives = 52/96 (54.17%), Query Frame = 2

Query:   68 EFRAELKVLTHVHHLNLVRLIGYC-FEGSLCVVYEFIENGNLSQHLRGSGRDPLAWSTRLQIALDSARGLEYIHEHTVPVYIHRDIKSANILIDKN 352
            +F  E +++  + H  L++L   C  E  + ++ E + +G+L ++L+  G   +  + ++ +A   A G+ Y+       YIHRD+ + N+L+ ++
Sbjct:  274 DFLREAQIMKSLRHPKLIQLYAVCTLEDPIYIITELMRHGSLQEYLQNDGGSKIRLTQQVDMAAQVASGMAYLESQN---YIHRDLAARNVLVGEH 366          

HSP 2 Score: 36.5798 bits (83), Expect = 9.889e-11
Identity = 21/57 (36.84%), Postives = 35/57 (61.40%), Query Frame = 1

Query:  364 DFGLTKLTEFGNASFYTSG--LQGTFGYFPPEAVSGN-VSPKTDVFAFGVVLYELIS 525
            DFGL ++ +  N   Y S   ++    +  PEA+  N  S K+DV++FG++LYE+I+
Sbjct:  373 DFGLARVFKVDNEDIYESKHEIKLPVKWTAPEAIRTNKFSIKSDVWSFGILLYEIIT 429