DY258525

BLAST of DY258525 vs. ExPASy Swiss-Prot
Match: DMPM_STRAD (O-demethylpuromycin-O-methyltransferase OS=Streptomyces alboniger GN=dmpM PE=4 SV=1)

HSP 1 Score: 100.138 bits (248), Expect = 2.911e-20
Identity = 63/219 (28.77%), Postives = 109/219 (49.77%), Query Frame = 3

Query:  216 VFLKSWSQLKDAILEGGIPFNRAHGVHVFEYAGLDPKFNKHFNTAMYNYTSLVMSNIL-ESYKGFDNIKQLVDVGGSLGITLQAITTKYPYIKGINFDQPH-------VIDHAPPHPRIEHVGGDMFQSVPKG-DAIFMKSVLHDWNDEHCLKLLKNCYKSIPEDGKVIVVESMLPEVPNTSIESKSNSHLDVLMMIQSPGGKERTRHGIMTLATGAGF 845
            VF ++WS    +I  G   F++  G   F Y    P+ +  F ++M   T  + + +  E    F +   +VD+GG+ G  L A+ + +P ++G+ FD P         +D A    R     GD F  VP G D   +KS+LHDW+D     +L+    ++P   +++VVE +LP+  ++S  +    +L  L M+ + GG+ER+   + +L +  GF
Sbjct:  138 VFRQAWSHFDHSIRTGEPAFDQVFGTDFFSYLSERPELSGTFTSSMREATRTMSTALAKEEEYDFSSYGTVVDIGGADGSLLAAVLSAHPGVEGVVFDSPEGARDAAATLDAAGVGERGRVETGDFFTRVPGGGDLYVLKSILHDWSDARSADILRTVRAAMPAHARLLVVEVLLPDTVDSS--AHPLGYLSDLYMLVNMGGRERSERDLRSLLSDTGF 354          

BLAST of DY258525 vs. ExPASy Swiss-Prot
Match: OMT7_DICDI (O-methyltransferase 7 OS=Dictyostelium discoideum GN=omt7 PE=3 SV=1)

HSP 1 Score: 96.6709 bits (239), Expect = 3.218e-19
Identity = 49/132 (37.12%), Postives = 78/132 (59.09%), Query Frame = 3

Query:  327 FNKHFNTAMYNYTSLVMSNILESYKGFDNIKQLVDVGGSLGITLQAITTKYPYIKGINFDQPHVIDHAPP---HPRIEHVGGDMFQSVPKGDAIFMKSVLHDWNDEHCLKLLKNCYKSIPEDGKVIVVESML 713
            F   FN  M  +++L +  I+++   F +   +VDVGGS G  +  +  KY  + GI FD   VI+ +     HPRIE+V G  F+SVP  D   +K++LHDW+DE CL++LK   KS+ E+ K+ + + ++
Sbjct:  151 FKYSFNQEMREFSNLSIPTIIKN-TDFSSFNTVVDVGGSHGRIVGELVKKYENLNGIVFDLETVINSSIEKIKHPRIEYVSGSFFESVPSADCYVLKNILHDWDDEKCLEILKTISKSMKENSKIFIFDEII 281          

BLAST of DY258525 vs. ExPASy Swiss-Prot
Match: HIOM_CHICK (Hydroxyindole O-methyltransferase OS=Gallus gallus GN=ASMT PE=2 SV=1)

HSP 1 Score: 89.3521 bits (220), Expect = 5.138e-17
Identity = 75/277 (27.08%), Postives = 119/277 (42.96%), Query Frame = 3

Query:   45 MMLDRILRLLASYSVVECSLDASGARRLYSLNSVSKYYVPNKDGVLLGPLIQIVQDKVFLKSWSQLKDAILEGGIPFNRAHGVHVFEYAGLDPKFNKH---FNTAMYNYTSLVMSNILESYKGFDNIKQLVDVGGSLGITLQAITTKYPYIKGINFDQPHVIDHA------PPHPRIEHVGGDMFQ-SVPKGDAIFMKSVLHDWNDEHCLKLLKNCYKSIPEDGKVIVVESMLPEVPNTSIESKSNSHLDVLMMIQSPGGKERTRHGIMTLATGAGF 845
            M ++R+L       ++   L   GA   Y    +S  Y+          ++    + V+L  W  L DA+ EG   + RA G+   +  G   +  +    F     +  S+   ++L ++       Q+ D+GG  G   Q     YP      +D P V+  A      P   RI    GD F+ S+P+ D   +  +LHDW+D+ C +LL   YK+    G V++VES+L E  +  +E++  S    L M+    GKERT      L   AGF
Sbjct:   59 MGMERLLDACVGLKLLAVELRREGA--FYRNTEISNIYLTKSSPKSQYHIMMYYSNTVYL-CWHYLTDAVREGRNQYERAFGISSKDLFGARYRSEEEMLKFLAGQNSIWSICGRDVLTAFD-LSPFTQIYDLGGGGGALAQECVFLYPNCTVTIYDLPKVVQVAKERLVPPEERRIAFHEGDFFKDSIPEADLYILSKILHDWDDKKCRQLLAEVYKACRPGGGVLLVESLLSEDRSGPVETQLYS----LNMLVQTEGKERTAVEYSELLGAAGF 327          

BLAST of DY258525 vs. ExPASy Swiss-Prot
Match: TCMN_STRGA (Multifunctional cyclase-dehydratase-3-O-methyl transferase tcmN OS=Streptomyces glaucescens GN=tcmN PE=1 SV=2)

HSP 1 Score: 82.8037 bits (203), Expect = 4.809e-15
Identity = 73/274 (26.64%), Postives = 129/274 (47.08%), Query Frame = 3

Query:   21 LTKNKDA-PMMLDRILRLLASYSVVECSLDASGARRLYSLNSVSK-YYVPNKDGVLLGPLIQIVQDKVFLKSWSQLKDAILEGGIPFNRAHGVHVFEYAGLDPKFNKHFNTAMYNYTS-LVMSNILESYKGFDNIKQLVDVGGSLGITLQAITTKYPYIKGINFDQPHVIDHAPP-------HPRIEHVGGDMFQS-VPKG-DAIFMKSVLHDWNDEHCLKLLKNCYKSI-PEDGKVIVVESMLPEVPNTSIESKSNSHLDVLMMIQSPGGKER 803
            L K  D   + L R+LR  AS  V      A G  R +S   +S      N DGVL  PL++    ++  + + ++  ++  G   F R  G   FE+   +P+  + F   M +++  LV+  + +  +G +   ++ D+GG  G  L  I  ++P+  G+  D P V   A P         R+  + GD F   VP G DA   K VLH+W+DE  + +L+   ++I  +D ++++ + ++   P    +      +D+L++    GG+ER
Sbjct:  203 LAKETDTHELSLYRVLRSAASVGVF-----AEGPVRTFSATPLSDGLRTGNPDGVL--PLVKYNNMELTRRPYDEIMHSVRTGEPAFRRVFGSSFFEHLEANPEAGEFFERFMAHWSRRLVLDGLAD--QGMERFSRIADLGGGDGWFLAQILRRHPHATGLLMDLPRVAASAGPVLEEAKVADRVTVLPGDFFTDPVPTGYDAYLFKGVLHNWSDERAVTVLRRVREAIGDDDARLLIFDQVM--APENEWDHAKLLDIDMLVLF---GGRER 462          

BLAST of DY258525 vs. ExPASy Swiss-Prot
Match: HIOM_BOVIN (Hydroxyindole O-methyltransferase OS=Bos taurus GN=ASMT PE=2 SV=2)

HSP 1 Score: 78.5666 bits (192), Expect = 9.069e-14
Identity = 63/228 (27.63%), Postives = 99/228 (43.42%), Query Frame = 3

Query:  231 WSQLKDAILEGGIPFNRAHGVHVFE-----YAGLDPKFNKHFNTAMYNYTSLVMSNILESYKGFDNIKQLVDVGGSLGITLQAITTKYPYIKGINFDQPHVIDHAPPH------PRIEHVGGDMFQ-SVPKGDAIFMKSVLHDWNDEHCLKLLKNCYKSIPEDGKVIVVESMLPEVPNTSIESKSNSHLDVLMMIQSPGGKERTRHGIMTLATGAGFGGISCELAIGS 878
            W  L +A+ EG   + +A G+   E     Y   D +    F   + +   L  + +L ++        + D+GG  G   +A  + YP  + I FD P V+  A  H       RI    GD F+ ++P+ D   +  VLHDW D  C  LL+  Y++    G ++V+ES+L    +T       + L  L M+    G+ERT      L   AGF  + C    G+
Sbjct:  117 WRHLAEAVREGRNQYLKAFGIPSEELFSAIYRSEDERLQ--FMQGLQDVWRLEGATVLAAFD-LSPFPLICDLGGGSGALAKACVSLYPGCRAIVFDIPGVVQIAKRHFSASEDERISFHEGDFFKDALPEADLYILARVLHDWTDAKCSHLLQRVYRACRTGGGILVIESLL----DTDGRGPLTTLLYSLNMLVQTEGRERTPAEYRALLGPAGFRDVRCRRTGGT 337          

BLAST of DY258525 vs. ExPASy Swiss-Prot
Match: HIOM_MACMU (Hydroxyindole O-methyltransferase OS=Macaca mulatta GN=ASMT PE=2 SV=1)

HSP 1 Score: 70.4774 bits (171), Expect = 2.470e-11
Identity = 59/215 (27.44%), Postives = 93/215 (43.26%), Query Frame = 3

Query:  231 WSQLKDAILEGGIPFNRAHGV---HVFEYAGLDPKFNKHFNTAMYNYTSLVMSNILESYKGFDNIKQLVDVGGSLGITLQAITTKYPYIKGINFDQPHVIDHAPPH---PRIEHVG---GDMFQS-VPKGDAIFMKSVLHDWNDEHCLKLLKNCYKSIPEDGKVIVVESMLPEVPNTSIESKSNSHLDVLMMIQSPGGKERTRHGIMTLATGAGF 845
            W  L DA+ EG   + +  GV    +F+           F  A+    S+   ++L ++        + D+GG  G   +   + YP  K   FD P V+  A  H   P  E +    GD F+  +P+ D   +  +LHDW D  C  LL+  Y +    G ++V+ES+L E     + ++  S    L M+    G+ERT      L + AGF
Sbjct:  117 WGHLADAVREGKNQYLQTFGVPAEDLFKAIYRSEGERLQFMQALQEVWSVNGRSVLTAFD-LSGFPLMCDLGGGPGALAKECLSLYPGCKVTVFDVPEVVRTAKQHFSFPEEEEIHLQEGDFFKDPLPEADLYILARILHDWADGKCSHLLERVYHTCKPGGGILVIESLLDEDRRGPLLTQLYS----LNMLVQTEGQERTPTHYHMLLSSAGF 326          

BLAST of DY258525 vs. ExPASy Swiss-Prot
Match: HIOM_HUMAN (Hydroxyindole O-methyltransferase OS=Homo sapiens GN=ASMT PE=2 SV=1)

HSP 1 Score: 69.3218 bits (168), Expect = 5.502e-11
Identity = 59/217 (27.19%), Postives = 92/217 (42.40%), Query Frame = 3

Query:  225 KSWSQLKDAILEGGIPFNRAHGV---HVFEYAGLDPKFNKHFNTAMYNYTSLVMSNILESYKGFDNIKQLVDVGGSLGITLQAITTKYPYIKGINFDQPHVIDHAPPH------PRIEHVGGDMFQS-VPKGDAIFMKSVLHDWNDEHCLKLLKNCYKSIPEDGKVIVVESMLPEVPNTSIESKSNSHLDVLMMIQSPGGKERTRHGIMTLATGAGF 845
            + W  L DA+ EG   +    GV    +F            F  A+    S+   ++L ++        + D+GG  G   +   + YP  K   FD P V+  A  H       +I+   GD F+  +P+ D   +  VLHDW D  C  LL+  Y +    G ++V+ES+L E     + ++  S    L M+    G+ERT      L + AGF
Sbjct:  115 RCWGHLADAVREGRNQYLETFGVPAEELFTAIYRSEGERLQFMQALQEVWSVNGRSVLTAFD-LSVFPLMCDLGGGAGALAKECMSLYPGCKITVFDIPEVVWTAKQHFSFQEEEQIDFQEGDFFKDPLPEADLYILARVLHDWADGKCSHLLERIYHTCKPGGGILVIESLLDEDRRGPLLTQLYS----LNMLVQTEGQERTPTHYHMLLSSAGF 326          

BLAST of DY258525 vs. ExPASy Swiss-Prot
Match: DMTA_DICDI (Des-methyl DIF-1 methyltransferase A OS=Dictyostelium discoideum GN=dmtA PE=1 SV=1)

HSP 1 Score: 68.5514 bits (166), Expect = 9.385e-11
Identity = 57/187 (30.48%), Postives = 90/187 (48.13%), Query Frame = 3

Query:  318 DPKFNKHFNTAMYNYTSLVMSNILESYKGFDNIKQLVDVGGSLGITLQAI--TTKYPYIKG-INFDQPHVIDH---------APPHPRIEHVGGDMF--QSVPKGDAIFMKSVLHDWNDEHCLKLLKNCYKSIPEDGKVIVVESMLPEVPNTSIESKSNSHLDV---LMMIQSPGGKERTRHGIMTL 827
            D   N HF+  M ++TS  +  ILE Y  F+  K +VD+GGS G  L++I  +++   ++  INFD P VI+          A    R   V  D+F     P  D   +K + H +ND+  L +L    KSI  +GKV V + +        ++ K+  +      L MI +  GKER+++   T+
Sbjct:  157 DKSLNAHFHNTMTSFTSDEIKTILE-YIDFNQYKSIVDLGGSSGELLKSIAKSSRGQLVESFINFDLPLVINQNKVNNENGAAEFDKRYSEVASDLFVDSDYPSADCYTLKFIFHMFNDDKVLTILDKISKSIKPNGKVYVFDHI--------VQPKNQPYAPFYFDLQMIVNFNGKERSQNEWKTI 334