DY259937

BLAST of DY259937 vs. ExPASy Swiss-Prot
Match: PIMT_HUMAN (Protein-L-isoaspartate(D-aspartate) O-methyltransferase OS=Homo sapiens GN=PCMT1 PE=1 SV=3)

HSP 1 Score: 139.043 bits (349), Expect = 4.454e-32
Identity = 79/176 (44.89%), Postives = 104/176 (59.09%), Query Frame = 2

Query:  191 WSGSGVNKNKAMVEHLQHYGVITSKKVSEVMETIDRACFVPDGTPPYVDSPMAIGYNATISAPHMHATCLQLLEENLKPGMHALDIGSGTGYLTACFALMVGPQGRAVGVEHLPELVASSIQNIEKSAAAPLLKKGSPSLHVGDGKKGGPNLPPMKQYIGRTAPPQNPPALIDPLK 718
            W   G + ++ ++ +L+  G+I + KV EVM   DR+ +      PY+DSP +IG+ ATISAPHMHA  L+LL + L  G  ALD+GSG+G LTACFA MVG  G+ +G++H+ ELV  SI N+ K     LL  G   L VGDG+ G     P        A P  P ALID LK
Sbjct:    3 WKSGGASHSE-LIHNLRKNGIIKTDKVFEVMLATDRSHYAKCN--PYMDSPQSIGFQATISAPHMHAYALELLFDQLHEGAKALDVGSGSGILTACFARMVGCTGKVIGIDHIKELVDDSINNVRKDDPT-LLSSGRVQLVVGDGRMGYAEEAPYDAIHVGAAAPVVPQALIDQLK 174          

BLAST of DY259937 vs. ExPASy Swiss-Prot
Match: PIMT_CAEEL (Protein-L-isoaspartate O-methyltransferase OS=Caenorhabditis elegans GN=pcm-1 PE=2 SV=1)

HSP 1 Score: 135.191 bits (339), Expect = 6.432e-31
Identity = 73/175 (41.71%), Postives = 104/175 (59.43%), Query Frame = 2

Query:  191 WSGSGVNKNKAMVEHLQHYGVITSKKVSEVMETIDRACFVPDGTPPYVDSPMAIGYNATISAPHMHATCLQLLEENLKPGMHALDIGSGTGYLTACFALMVGPQGRAVGVEHLPELVASSIQNIEKSAAAPLLKKGSPSLHVGDGKKGGPNLPPMKQYIGRTAPPQNPPALIDPL 715
            W  SG + N  ++++L++  V  S++  + M+++DR  F P    PY D+P  IGYNAT+SAPHMHA  L  L+ +L  G  ALD+GSG+GYLT C A+MVG  G  VG+EH+P+LV  S +NI K  +   L++G+  +  GDG++G     P        A    P AL D L
Sbjct:    3 WRSSG-STNSELIDNLRNNRVFASQRAYDAMKSVDRGDFAPRA--PYEDAPQRIGYNATVSAPHMHAAALDYLQNHLVAGAKALDVGSGSGYLTVCMAMMVGRNGTVVGIEHMPQLVELSEKNIRKHHSEQ-LERGNVIIIEGDGRQGFAEKAPYNAIHVGAASKGVPKALTDQL 173          

BLAST of DY259937 vs. ExPASy Swiss-Prot
Match: PIMT_SCHPO (Probable protein-L-isoaspartate O-methyltransferase OS=Schizosaccharomyces pombe GN=pcm2 PE=2 SV=1)

HSP 1 Score: 127.872 bits (320), Expect = 1.027e-28
Identity = 72/183 (39.34%), Postives = 104/183 (56.83%), Query Frame = 2

Query:  188 YWSGSGVNKNKAMVEHLQHYGVITSKKVSEVMETIDRACFVPDGTPPYVDSPMAIGYNATISAPHMHATCLQLLEENLKPGMHALDIGSGTGYLTACFALMVGPQGRAVGVEHLPELVASSIQNIEK-----SAAAPLLKKGSPSLHVGDGKKGGPNLPPMKQYIGRTAPPQNPPALIDPLKT 721
            +WS + ++ N A+V+HL     +T+++  + M    R+ + P    PY+DSP +IGY  TISAPHMHAT LQ LE  L+PG  ALDIGSG+GYL A  A MV P G   G+EH+P+LV +S +N+ K          + K+    ++VGDG+ G              +  + P  L+D LK+
Sbjct:    2 FWSFN-LSSNAALVQHLVESKFLTNQRAIKAMNATSRSFYCP--LSPYMDSPQSIGYGVTISAPHMHATALQELEPVLQPGCSALDIGSGSGYLVAAMARMVAPNGTVKGIEHIPQLVETSKKNLLKDINHDEVLMEMYKEKRLQINVGDGRMGTSEDEKFDAIHVGASASELPQKLVDQLKS 181          

BLAST of DY259937 vs. ExPASy Swiss-Prot
Match: PIMT_DROME (Protein-L-isoaspartate(D-aspartate) O-methyltransferase OS=Drosophila melanogaster GN=Pcmt PE=1 SV=2)

HSP 1 Score: 123.635 bits (309), Expect = 1.937e-27
Identity = 75/181 (41.44%), Postives = 102/181 (56.35%), Query Frame = 2

Query:  191 WSGSGVNKNKAMVEHLQHYGVITSKKVSEVMETIDRACFVPDGTPPYVDSPMAIGYNATISAPHMHATCLQLLEENLKPGMHALDIGSGTGYLTACFALMVGPQG-----RAVGVEHLPELVASSIQNIEKSAAAPLLKKGSPSLHVGDGKKG-GPNLPPMKQYIGRTAPPQNPPALIDPL 715
            W   G N N+ ++  L+ +GVI S  V++ M+  DR  + P    PY+D+P  IG   TISAPHMHA  L+ L ++LKPG   LD+GSG+GYLTACF   +  +G     R VG+EH  ELV  S  N+     + +L  G   +  GDG+KG  PN P    ++G  A P  P  LI+ L
Sbjct:    3 WRSVGAN-NEDLIRQLKDHGVIASDAVAQAMKETDRKHYSPRN--PYMDAPQPIGGGVTISAPHMHAFALEYLRDHLKPGARILDVGSGSGYLTACFYRYIKAKGVDADTRIVGIEHQAELVRRSKANLNTDDRS-MLDSGQLLIVEGDGRKGYPPNAPYNAIHVG-AAAPDTPTELINQL 178          

BLAST of DY259937 vs. ExPASy Swiss-Prot
Match: PIMT_DICDI (Probable protein-L-isoaspartate O-methyltransferase OS=Dictyostelium discoideum GN=pcmA PE=3 SV=1)

HSP 1 Score: 108.227 bits (269), Expect = 8.420e-23
Identity = 70/167 (41.92%), Postives = 94/167 (56.29%), Query Frame = 2

Query:  236 LQHYG--VITSKKVSEVMETIDRACFVPDGTP--PYVDSPMAIGYNATISAPHMHATCLQLLEENLKPGMH-ALDIGSGTGYLTACFALMVGPQGRAVGVEHLPELVASSIQNIEKSAAAPLLKKGSPSLHVGDGKKGGPNLPPMKQYIGRTAPP-QNPPALIDPLK 718
            L HY   ++ +K + E ++ +DR  F+ +     PY D P  IGYNATISAPHMHA  L LL + +      ALDIGSG+GY+TAC   ++G  GR +GVEH+PEL+  SI++I++  +  L         VGDG KG   L     Y+G      Q    LID LK
Sbjct:   57 LLHYQKRMVLNKTIVETLKFVDRKLFLENKNVENPYYDEPKPIGYNATISAPHMHALMLDLLADRIPMSNGVALDIGSGSGYVTACLGHLMGCTGRVIGVEHIPELIERSIESIKRLDSTLL---DRIQFLVGDGIKGWKQLKYDIIYLGAAIESLQVARELIDQLK 220          

BLAST of DY259937 vs. ExPASy Swiss-Prot
Match: PIMT_METKA (Protein-L-isoaspartate O-methyltransferase OS=Methanopyrus kandleri GN=pcm PE=3 SV=1)

HSP 1 Score: 103.99 bits (258), Expect = 1.588e-21
Identity = 64/167 (38.32%), Postives = 92/167 (55.09%), Query Frame = 2

Query:  224 MVEHLQHYGVITSKKVSEVMETIDRACFVPDGTPP--YVDSPMAIGYNATISAPHMHATCLQLLEENLKPGMHALDIGSGTGYLTACFALMVGPQGRAVGVEHLPELVASSIQNIEKSAAAPLLKKGSPSLHVGDGKKGGPNLPPMKQYIGRTAPPQNPPALIDPLK 718
            +VE L+  G I S +V+E M  + R  FVP+      YVDSP+ IG   TISAPHM A   +LL+   +PG   L++G+G+GY  A  A +V P GR + VE +PEL   +  N++K+     +K     + VGDG KG P   P  + +     P  P +L++ LK
Sbjct:   15 LVERLKSLGYIRSNRVAEAMLKVPRHEFVPEDLRDRAYVDSPLPIGRGQTISAPHMVAIMTELLDP--RPGHKVLEVGAGSGYHAAVVAELVKPDGRVITVERIPELADFARNNLKKTGYDRFVK-----VLVGDGTKGYPPEAPYDRILVTAGAPDVPESLLEQLK 174          

BLAST of DY259937 vs. ExPASy Swiss-Prot
Match: PIMT_AERPE (Protein-L-isoaspartate O-methyltransferase OS=Aeropyrum pernix GN=pcm PE=3 SV=2)

HSP 1 Score: 103.99 bits (258), Expect = 1.588e-21
Identity = 64/166 (38.55%), Postives = 91/166 (54.82%), Query Frame = 2

Query:  224 MVEHLQHYGVITSKKVSEVMETIDRACFVPDGTP--PYVDSPMAIGYNATISAPHMHATCLQLLEENLKPGMHALDIGSGTGYLTACFALMVGPQGRAVGVEHLPELVASSIQNIEKSAAAPLLKKGSPSLHVGDGKKGGPNLPPMKQYIGRTAPPQNPPALIDPL 715
            MVE L+  G++TS++V E M  + R  FVP       Y D P+ IG+  TISAP +    LQLL+   +PG   LD+G+G+GY +A  A +V P GR   VE +PEL   + +N+EK+       +G   + VGDG KG P   P  +     A P+ P  L++ L
Sbjct:   41 MVEQLRRSGLVTSRRVLEAMARVPRHLFVPPEYRGMAYEDRPLPIGHGQTISAPGVVGRMLQLLDP--QPGEKVLDVGAGSGYQSALLAELVTPGGRVYAVERIPELAEYARENLEKTG-----YRGVVEVVVGDGSKGLPQHAPYHRIKVAAAAPKPPKPLVEQL 199          

BLAST of DY259937 vs. ExPASy Swiss-Prot
Match: PIMT_FERNB (Protein-L-isoaspartate O-methyltransferase OS=Fervidobacterium nodosum (strain ATCC 35602 / DSM 5306 / Rt17-B1) GN=pcm PE=3 SV=1)

HSP 1 Score: 99.7525 bits (247), Expect = 2.995e-20
Identity = 65/167 (38.92%), Postives = 88/167 (52.69%), Query Frame = 2

Query:  224 MVEHLQHYGVITSKKVSEVMETIDRACFVPDGTPP--YVDSPMAIGYNATISAPHMHATCLQLLEENLKPGMHALDIGSGTGYLTACFALMVGPQGRAVGVEHLPELVASSIQNIEKSAAAPLLKKGSPSLHVGDGKKGGPNLPPMKQYIGRTAPPQNPPALIDPLK 718
            + EHLQ+YGV  S+K+ E M  +DR  FVP       Y+D P+ IGY  TISAPHM     + LE  LK G   L+IG+G+GY  A  +L+VG  G    +E +PELV  + + I       LL   + ++ VGDGK+G     P  +          P  LI+ LK
Sbjct:    2 LFEHLQYYGV--SRKIIEAMNKVDRKLFVPSELQESAYLDIPLPIGYGQTISAPHMVGMMCEYLE--LKDGDRVLEIGTGSGYNAAVMSLLVGESGWIYTIERIPELVQEAQKRIN------LLGINNITIIVGDGKEGLEEYAPFDKITVTCYAKHIPKKLIEQLK 158          

BLAST of DY259937 vs. ExPASy Swiss-Prot
Match: PIMT_HYPBU (Protein-L-isoaspartate O-methyltransferase OS=Hyperthermus butylicus (strain DSM 5456 / JCM 9403) GN=pcm PE=3 SV=1)

HSP 1 Score: 98.2117 bits (243), Expect = 8.713e-20
Identity = 64/176 (36.36%), Postives = 90/176 (51.14%), Query Frame = 2

Query:  218 KAMVEHLQHYGVITSKKVSEVMETIDRACFVPDGTP--PYVDSPMAIGYNATISAPHMHATCLQLLEENLKPGMHALDIGSGTGYLTACFALMVGPQ-------GRAVGVEHLPELVASSIQNIEKSAAAPLLKKGSPSLHVGDGKKGGPNLPPMKQYIGRTAPPQNPPALIDPLK 718
            + +VE L   G I S+ V   M  + R  FVPD      Y D+P+ IG+  TISAPHM A   +  +  LKPGM  L++G+G+GY  A  A +V P        G    +E +PEL   + +N+E++  A  +     ++ VGDG +G P   P  + I   A P  P  LID LK
Sbjct:   16 RRLVERLVREGYIRSEHVKRAMLRVPRELFVPDELRHLAYEDTPLPIGHGQTISAPHMVAMMTEYAD--LKPGMKVLEVGAGSGYHAAVMAEVVAPSDEPREHWGHVYTIERIPELAEFARRNLERAGYADRV-----TVIVGDGSRGYPEKAPYDRIIVTAAAPDIPGPLIDQLK 184          

BLAST of DY259937 vs. ExPASy Swiss-Prot
Match: PIMT_METTP (Protein-L-isoaspartate O-methyltransferase OS=Methanosaeta thermophila (strain DSM 6194 / PT) GN=pcm PE=3 SV=1)

HSP 1 Score: 95.9005 bits (237), Expect = 4.324e-19
Identity = 65/190 (34.21%), Postives = 100/190 (52.63%), Query Frame = 2

Query:  212 KNKAMVEHLQHYGVITSKKVSEVMETIDRACFVPDGTPP--YVDSPMAIGYNATISAPHMHATCLQLLEENLKPGMHALDIGSGTGYLTACFALMVGPQGRAVGVEHLPELVASSIQNIEKSAAAPLLKKGSPSLHVGDGKKGGPNLPPMKQYIGRTAPPQNPPALIDPLKTR-KPNGDS--PLAKYSPE 766
            + + ++E L++Y    S++V E M  + R  FVP+   P  Y D P+ IG+  TISAPHM A    LL+  L+ GM  L++G G GY  A  A +VGP G    VE +PELV  + +N+E++      +  + S+ +GDG  G     P      R +   + P + +PLK + +P G    P+  YS +
Sbjct:    2 RKERLIESLRNY---VSERVVEAMSRVPRELFVPEELRPMAYEDRPLPIGHGQTISAPHMVAMMCDLLD--LREGMKVLEVGGGCGYHAAVMAELVGPSGHVYSVERIPELVEMARRNLERA------RYRNVSMILGDGTLGYSEQAP----YDRISVAASAPDIPEPLKEQLRPGGRMVIPVGSYSQD 176