DY260217

BLAST of DY260217 vs. ExPASy Swiss-Prot
Match: MELK_HUMAN (Maternal embryonic leucine zipper kinase OS=Homo sapiens GN=MELK PE=1 SV=3)

HSP 1 Score: 202.216 bits (513), Expect = 4.231e-51
Identity = 107/244 (43.85%), Postives = 155/244 (63.52%), Query Frame = 1

Query:   79 YELGRMLGHGTFAKVYLARNLQTGKSMAXXXXXXXXXXXXXXXEQIKREISVMKMVKHKHIVELHEVMASKSKIYFAMDLVKGGELFNKI-AKGRLREDVARVYFQQLISAVDFCHSRGVYHRDLKPENLLLDEDGNLKVTDFGLSAFSEHLKQDGLLHTTCGTPAYVAPEVISKKGYDGAKADIWSCGVILYVLLASFLPFQDDNIVSMYRKIYRGDFKCPPWFSSEARRLITKLLDPNPNSR 807
            YEL   +G G FAKV LA ++ TG+ +A                +IK EI  +K ++H+HI +L+ V+ + +KI+  ++   GGELF+ I ++ RL E+  RV F+Q++SAV + HS+G  HRDLKPENLL DE   LK+ DFGL A  +  K D  L T CG+ AY APE+I  K Y G++AD+WS G++LYVL+  FLPF DDN++++Y+KI RG +  P W S  +  L+ ++L  +P  R
Sbjct:   11 YELHETIGTGGFAKVKLACHILTGEMVAIKIMDKNTLGSDLP--RIKTEIEALKNLRHQHICQLYHVLETANKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQIVSAVAYVHSQGYAHRDLKPENLLFDEYHKLKLIDFGLCAKPKGNK-DYHLQTCCGSLAYAAPELIQGKSYLGSEADVWSMGILLYVLMCGFLPFDDDNVMALYKKIMRGKYDVPKWLSPSSILLLQQMLQVDPKKR 251          

BLAST of DY260217 vs. ExPASy Swiss-Prot
Match: AAPK2_RAT (5'-AMP-activated protein kinase catalytic subunit alpha-2 OS=Rattus norvegicus GN=Prkaa2 PE=1 SV=1)

HSP 1 Score: 202.216 bits (513), Expect = 4.231e-51
Identity = 108/247 (43.72%), Postives = 150/247 (60.73%), Query Frame = 1

Query:   73 GKYELGRMLGHGTFAKVYLARNLQTGKSMAXXXXXXXXXXXXXXXEQIKREISVMKMVKHKHIVELHEVMASKSKIYFAMDLVKGGELFNKIAK-GRLREDVARVYFQQLISAVDFCHSRGVYHRDLKPENLLLDEDGNLKVTDFGLSAFSEHLKQDG-LLHTTCGTPAYVAPEVISKKGYDGAKADIWSCGVILYVLLASFLPFQDDNIVSMYRKIYRGDFKCPPWFSSEARRLITKLLDPNPNSR 807
            G Y LG  LG GTF KV +  +  TG  +A                +IKREI  +K+ +H HI++L++V+++ +  +  M+ V GGELF+ I K GR+ E  AR  FQQ++SAVD+CH   V HRDLKPEN+LLD   N K+ DFGLS    ++  DG  L T+CG+P Y APEVIS + Y G + DIWSCGVILY LL   LPF D+++ ++++KI  G F  P + +     L+  +L  +P  R
Sbjct:   14 GHYVLGDTLGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKLFRHPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEVEARRLFQQILSAVDYCHRHMVVHRDLKPENVLLDAQMNAKIADFGLS----NMMSDGEFLRTSCGSPNYAAPEVISGRLYAGPEVDIWSCGVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPEYLNRSIATLLMHMLQVDPLKR 256          

BLAST of DY260217 vs. ExPASy Swiss-Prot
Match: AAPK2_PONAB (5'-AMP-activated protein kinase catalytic subunit alpha-2 OS=Pongo abelii GN=PRKAA2 PE=2 SV=1)

HSP 1 Score: 202.216 bits (513), Expect = 4.231e-51
Identity = 108/247 (43.72%), Postives = 150/247 (60.73%), Query Frame = 1

Query:   73 GKYELGRMLGHGTFAKVYLARNLQTGKSMAXXXXXXXXXXXXXXXEQIKREISVMKMVKHKHIVELHEVMASKSKIYFAMDLVKGGELFNKIAK-GRLREDVARVYFQQLISAVDFCHSRGVYHRDLKPENLLLDEDGNLKVTDFGLSAFSEHLKQDG-LLHTTCGTPAYVAPEVISKKGYDGAKADIWSCGVILYVLLASFLPFQDDNIVSMYRKIYRGDFKCPPWFSSEARRLITKLLDPNPNSR 807
            G Y LG  LG GTF KV +  +  TG  +A                +IKREI  +K+ +H HI++L++V+++ +  +  M+ V GGELF+ I K GR+ E  AR  FQQ++SAVD+CH   V HRDLKPEN+LLD   N K+ DFGLS    ++  DG  L T+CG+P Y APEVIS + Y G + DIWSCGVILY LL   LPF D+++ ++++KI  G F  P + +     L+  +L  +P  R
Sbjct:   14 GHYVLGDTLGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKLFRHPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLS----NIMSDGEFLRTSCGSPNYAAPEVISGRLYAGPEVDIWSCGVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPEYLNRSVATLLMHMLQVDPLKR 256          

BLAST of DY260217 vs. ExPASy Swiss-Prot
Match: AAPK2_HUMAN (5'-AMP-activated protein kinase catalytic subunit alpha-2 OS=Homo sapiens GN=PRKAA2 PE=1 SV=2)

HSP 1 Score: 202.216 bits (513), Expect = 4.231e-51
Identity = 108/247 (43.72%), Postives = 150/247 (60.73%), Query Frame = 1

Query:   73 GKYELGRMLGHGTFAKVYLARNLQTGKSMAXXXXXXXXXXXXXXXEQIKREISVMKMVKHKHIVELHEVMASKSKIYFAMDLVKGGELFNKIAK-GRLREDVARVYFQQLISAVDFCHSRGVYHRDLKPENLLLDEDGNLKVTDFGLSAFSEHLKQDG-LLHTTCGTPAYVAPEVISKKGYDGAKADIWSCGVILYVLLASFLPFQDDNIVSMYRKIYRGDFKCPPWFSSEARRLITKLLDPNPNSR 807
            G Y LG  LG GTF KV +  +  TG  +A                +IKREI  +K+ +H HI++L++V+++ +  +  M+ V GGELF+ I K GR+ E  AR  FQQ++SAVD+CH   V HRDLKPEN+LLD   N K+ DFGLS    ++  DG  L T+CG+P Y APEVIS + Y G + DIWSCGVILY LL   LPF D+++ ++++KI  G F  P + +     L+  +L  +P  R
Sbjct:   14 GHYVLGDTLGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKLFRHPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLS----NMMSDGEFLRTSCGSPNYAAPEVISGRLYAGPEVDIWSCGVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPEYLNRSVATLLMHMLQVDPLKR 256          

BLAST of DY260217 vs. ExPASy Swiss-Prot
Match: Y7165_DICDI (Probable serine/threonine-protein kinase DDB_G0277165 OS=Dictyostelium discoideum GN=DDB_G0277165 PE=3 SV=1)

HSP 1 Score: 201.83 bits (512), Expect = 5.525e-51
Identity = 102/247 (41.30%), Postives = 152/247 (61.54%), Query Frame = 1

Query:   73 GKYELGRMLGHGTFAKVYLARNLQTG-KSMAXXXXXXXXXXXXXXXEQIKREISVMKMVKHKHIVELHEVMASKSKIYFAMDLVKGGELFNKIA-KGRLREDVARVYFQQLISAVDFCHSRGVYHRDLKPENLLLDEDGNLKVTDFGLSAFSEHLKQDGLLHTTCGTPAYVAPEVISKKGYDGAKADIWSCGVILYVLLASFLPFQDDNIVSMYRKIYRGDFKCPPWFSSEARRLITKLLDPNPNSR 807
            G + +G+ LG GT  KV L  +  TG K                   +I+REI +MK++ H + ++++EV  +   ++  ++ V+GGELF+ +  KG L    A  +FQQ+I  +++CHSR + HRDLKPENLLL  D  +K+ DFG+ +    +++D LLHT+CG+P Y +PEV+S   YDG KAD+WSCGVILY LL   LPF D+NI  +  K+  G F  PP+   +A+ L+TK+L  +P+ R
Sbjct:    7 GPFIIGKTLGQGTTGKVKLGFHKDTGFKVGIKIINKELLINKPSMRRKIEREIVLMKLIDHPNAMKMYEVYETSKYLFLILEYVEGGELFDYLVEKGGLESGEALFFFQQIIIGLEYCHSRNICHRDLKPENLLLSGDKRIKIADFGMGSI---VRKDMLLHTSCGSPHYASPEVVSGIDYDGQKADVWSCGVILYALLTGKLPFDDENIRRLLNKVKNGAFSMPPYIHKDAQDLLTKMLTVDPSKR 250          

BLAST of DY260217 vs. ExPASy Swiss-Prot
Match: BRSK2_MOUSE (BR serine/threonine-protein kinase 2 OS=Mus musculus GN=Brsk2 PE=1 SV=2)

HSP 1 Score: 201.83 bits (512), Expect = 5.525e-51
Identity = 103/256 (40.23%), Postives = 153/256 (59.77%), Query Frame = 1

Query:   25 TSNSNGGGDDRPTLLHGKYELGRMLGHGTFAKVYLARNLQTGKSMAXXXXXXXXXXXXXXXEQIKREISVMKMVKHKHIVELHEVMASKSKIYFAMDLVKGGELFNKIAK-GRLREDVARVYFQQLISAVDFCHSRGVYHRDLKPENLLLDEDGNLKVTDFGLSAFSEHLKQDGLLHTTCGTPAYVAPEVISKKGYDGAKADIWSCGVILYVLLASFLPFQDDNIVSMYRKIYRGDFKCPPWFSSEARRLITKLLD 789
            TS    GG  +     G Y L + LG G    V L  +  T + +A               + ++REI+++K+++H H+++LH+V  +K  +Y  ++ V GGELF+ + K GRL    AR +F+Q+ISA+DFCHS  + HRDLKPENLLLDE  N+++ DFG+++       D LL T+CG+P Y  PEVI  + YDG KAD+WSCGVIL+ LL   LPF DDN+  +  K+ RG F  P +   + + L+  +++
Sbjct:    2 TSTGKDGGGAQHAQYVGPYRLEKTLGKGQTGLVKLGIHCVTCQKVAIKIVNREKLSESVLMK-VEREIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHSICHRDLKPENLLLDERNNIRIADFGMASLQVG---DSLLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILFALLVGALPFDDDNLRQLLEKVKRGVFHMPHFIPPDCQSLLRGMIE 253          

BLAST of DY260217 vs. ExPASy Swiss-Prot
Match: MARK2_RAT (Serine/threonine-protein kinase MARK2 OS=Rattus norvegicus GN=Mark2 PE=1 SV=1)

HSP 1 Score: 201.445 bits (511), Expect = 7.216e-51
Identity = 104/260 (40.00%), Postives = 156/260 (60.00%), Query Frame = 1

Query:   31 NSNGGGDDRPTLLHGKYELGRMLGHGTFAKVYLARNLQTGKSMAXXXXXXXXXXXXXXXEQIKREISVMKMVKHKHIVELHEVMASKSKIYFAMDLVKGGELFNK-IAKGRLREDVARVYFQQLISAVDFCHSRGVYHRDLKPENLLLDEDGNLKVTDFGLSAFSEHLKQDGLLHTTCGTPAYVAPEVISKKGYDGAKADIWSCGVILYVLLASFLPFQDDNIVSMYRKIYRGDFKCPPWFSSEARRLITKLLDPNPNSR 807
            NS    D++P +  G Y L + +G G FAKV LAR++ TGK +A               +++ RE+ +MK++ H +IV+L EV+ ++  +Y  M+   GGE+F+  +A GR++E  AR  F+Q++SAV +CH + + HRDLK ENLLLD D N+K+ DFG   FS        L T CG+P Y APE+   K YDG + D+WS GVILY L++  LPF   N+  +  ++ RG ++ P + S++   L+ K L  NP+ R
Sbjct:   39 NSATSADEQPHI--GNYRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSL-QKLFREVRIMKVLNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFIVHRDLKAENLLLDADMNIKIADFG---FSNEFTFGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLILNPSKR 292          

BLAST of DY260217 vs. ExPASy Swiss-Prot
Match: MARK2_HUMAN (Serine/threonine-protein kinase MARK2 OS=Homo sapiens GN=MARK2 PE=1 SV=2)

HSP 1 Score: 201.445 bits (511), Expect = 7.216e-51
Identity = 104/260 (40.00%), Postives = 156/260 (60.00%), Query Frame = 1

Query:   31 NSNGGGDDRPTLLHGKYELGRMLGHGTFAKVYLARNLQTGKSMAXXXXXXXXXXXXXXXEQIKREISVMKMVKHKHIVELHEVMASKSKIYFAMDLVKGGELFNK-IAKGRLREDVARVYFQQLISAVDFCHSRGVYHRDLKPENLLLDEDGNLKVTDFGLSAFSEHLKQDGLLHTTCGTPAYVAPEVISKKGYDGAKADIWSCGVILYVLLASFLPFQDDNIVSMYRKIYRGDFKCPPWFSSEARRLITKLLDPNPNSR 807
            NS    D++P +  G Y L + +G G FAKV LAR++ TGK +A               +++ RE+ +MK++ H +IV+L EV+ ++  +Y  M+   GGE+F+  +A GR++E  AR  F+Q++SAV +CH + + HRDLK ENLLLD D N+K+ DFG   FS        L T CG+P Y APE+   K YDG + D+WS GVILY L++  LPF   N+  +  ++ RG ++ P + S++   L+ K L  NP+ R
Sbjct:   39 NSATSADEQPHI--GNYRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSL-QKLFREVRIMKVLNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFIVHRDLKAENLLLDADMNIKIADFG---FSNEFTFGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLILNPSKR 292          

BLAST of DY260217 vs. ExPASy Swiss-Prot
Match: SNF1_CANGA (Carbon catabolite-derepressing protein kinase OS=Candida glabrata GN=SNF1 PE=3 SV=2)

HSP 1 Score: 201.06 bits (510), Expect = 9.425e-51
Identity = 107/247 (43.32%), Postives = 158/247 (63.97%), Query Frame = 1

Query:   73 GKYELGRMLGHGTFAKVYLARNLQTGKSMAXXXXXXXXXXXXXXXEQIKREISVMKMVKHKHIVELHEVMASKSKIYFAMDLVKGGELFNKIA-KGRLREDVARVYFQQLISAVDFCHSRGVYHRDLKPENLLLDEDGNLKVTDFGLSAFSEHLKQDG-LLHTTCGTPAYVAPEVISKKGYDGAKADIWSCGVILYVLLASFLPFQDDNIVSMYRKIYRGDFKCPPWFSSEARRLITKLLDPNPNSR 807
            G Y++ + LG G+F KV LA ++ TG+ +A                +I+REIS +++++H HI++L++V+ SK +I   ++   G ELF+ I  + ++ E  AR +FQQ+ISAV++CH   + HRDLKPENLLLDE  N+K+ DFGLS    ++  DG  L T+CG+P Y APEVIS K Y G + D+WSCGVILYV+L   LPF D++I  +++ I  G +  P + S  A  LI ++L  NP +R
Sbjct:   37 GNYQIVKTLGEGSFGKVKLAYHVTTGQKVALKIINKKVLAKSDMQGRIEREISYLRLLRHPHIIKLYDVIKSKDEIIMVIEYA-GNELFDYIVQRNKMSEQEARRFFQQIISAVEYCHRHKIVHRDLKPENLLLDEHLNVKIADFGLS----NIMTDGNFLKTSCGSPNYAAPEVISGKLYAGPEVDVWSCGVILYVMLCRRLPFDDESIPVLFKNISNGVYTLPKFLSPGASDLIKRMLIVNPLNR 278          

BLAST of DY260217 vs. ExPASy Swiss-Prot
Match: SNF1_YEAST (Carbon catabolite-derepressing protein kinase OS=Saccharomyces cerevisiae GN=SNF1 PE=1 SV=1)

HSP 1 Score: 199.904 bits (507), Expect = 2.100e-50
Identity = 107/247 (43.32%), Postives = 157/247 (63.56%), Query Frame = 1

Query:   73 GKYELGRMLGHGTFAKVYLARNLQTGKSMAXXXXXXXXXXXXXXXEQIKREISVMKMVKHKHIVELHEVMASKSKIYFAMDLVKGGELFNKIA-KGRLREDVARVYFQQLISAVDFCHSRGVYHRDLKPENLLLDEDGNLKVTDFGLSAFSEHLKQDG-LLHTTCGTPAYVAPEVISKKGYDGAKADIWSCGVILYVLLASFLPFQDDNIVSMYRKIYRGDFKCPPWFSSEARRLITKLLDPNPNSR 807
            G Y++ + LG G+F KV LA +  TG+ +A                +I+REIS +++++H HI++L++V+ SK +I   ++   G ELF+ I  + ++ E  AR +FQQ+ISAV++CH   + HRDLKPENLLLDE  N+K+ DFGLS    ++  DG  L T+CG+P Y APEVIS K Y G + D+WSCGVILYV+L   LPF D++I  +++ I  G +  P + S  A  LI ++L  NP +R
Sbjct:   53 GNYQIVKTLGEGSFGKVKLAYHTTTGQKVALKIINKKVLAKSDMQGRIEREISYLRLLRHPHIIKLYDVIKSKDEIIMVIEYA-GNELFDYIVQRDKMSEQEARRFFQQIISAVEYCHRHKIVHRDLKPENLLLDEHLNVKIADFGLS----NIMTDGNFLKTSCGSPNYAAPEVISGKLYAGPEVDVWSCGVILYVMLCRRLPFDDESIPVLFKNISNGVYTLPKFLSPGAAGLIKRMLIVNPLNR 294