DY262745

BLAST of DY262745 vs. ExPASy Swiss-Prot
Match: MARK3_RAT (MAP/microtubule affinity-regulating kinase 3 OS=Rattus norvegicus GN=Mark3 PE=2 SV=1)

HSP 1 Score: 179.489 bits (454), Expect = 3.147e-44
Identity = 86/224 (38.39%), Postives = 140/224 (62.50%), Query Frame = 2

Query:  206 GKYEMGRMLGQGTFAKVYYGKNLVTQESVAIKVINKDQVKKQGLMEQIKREISVMRLVKHPNIVELKEVMATKTKVFFVIEYVKGGELFAK-VLKGKLKEESARKYFQQLISAVDFCHSRGVYHRDLKPENLLLDENGNLKVSDFGLSALPEQLWNDGLLHTQCGTPAYVAPEVLRKKGYDGAKSDIWSCXXXXXXXXXXXXPFQNENIMKMYRKIFKAEYEFP 874
            G Y + + +G+G FAKV   ++++T   VAIK+I+K Q+    L +++ RE+ +M+++ HPNIV+L EV+ T+  ++ ++EY  GGE+F   V  G++KE+ AR  F+Q++SAV +CH + + HRDLK ENLLLD + N+K++DFG S    +      L T CG+P Y APE+ + K YDG + D+WS             PF  +N+ ++  ++ + +Y  P
Sbjct:   54 GNYRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSL-QKLFREVRIMKILNHPNIVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKRIVHRDLKAENLLLDADMNIKITDFGFS---NEFTVGSKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIP 273          

BLAST of DY262745 vs. ExPASy Swiss-Prot
Match: MARK3_MOUSE (MAP/microtubule affinity-regulating kinase 3 OS=Mus musculus GN=Mark3 PE=1 SV=2)

HSP 1 Score: 179.489 bits (454), Expect = 3.147e-44
Identity = 86/224 (38.39%), Postives = 140/224 (62.50%), Query Frame = 2

Query:  206 GKYEMGRMLGQGTFAKVYYGKNLVTQESVAIKVINKDQVKKQGLMEQIKREISVMRLVKHPNIVELKEVMATKTKVFFVIEYVKGGELFAK-VLKGKLKEESARKYFQQLISAVDFCHSRGVYHRDLKPENLLLDENGNLKVSDFGLSALPEQLWNDGLLHTQCGTPAYVAPEVLRKKGYDGAKSDIWSCXXXXXXXXXXXXPFQNENIMKMYRKIFKAEYEFP 874
            G Y + + +G+G FAKV   ++++T   VAIK+I+K Q+    L +++ RE+ +M+++ HPNIV+L EV+ T+  ++ ++EY  GGE+F   V  G++KE+ AR  F+Q++SAV +CH + + HRDLK ENLLLD + N+K++DFG S    +      L T CG+P Y APE+ + K YDG + D+WS             PF  +N+ ++  ++ + +Y  P
Sbjct:   54 GNYRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSL-QKLFREVRIMKILNHPNIVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKRIVHRDLKAENLLLDADMNIKIADFGFS---NEFTVGSKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIP 273          

BLAST of DY262745 vs. ExPASy Swiss-Prot
Match: PAR1_CAEEL (Serine/threonine-protein kinase par-1 OS=Caenorhabditis elegans GN=par-1 PE=1 SV=1)

HSP 1 Score: 179.104 bits (453), Expect = 4.110e-44
Identity = 88/229 (38.43%), Postives = 142/229 (62.01%), Query Frame = 2

Query:  191 RNILFGKYEMGRMLGQGTFAKVYYGKNLVTQESVAIKVINKDQVKKQGLMEQIKREISVMRLVKHPNIVELKEVMATKTKVFFVIEYVKGGELFAK-VLKGKLKEESARKYFQQLISAVDFCHSRGVYHRDLKPENLLLDENGNLKVSDFGLSALPEQLWNDGLLHTQCGTPAYVAPEVLRKKGYDGAKSDIWSCXXXXXXXXXXXXPFQNENIMKMYRKIFKAEYEFP 874
            +++  GKY++ + +G+G FAKV   K+++T   VAIK+I+K  +    L +++ RE+ +M+ + HPNIV+L +VM T+  ++ V+EY  GGE+F   V  G++KE+ AR  F+Q++SAV + HS+ + HRDLK ENLLLD++ N+K++DFG S           L T CG+P Y APE+   K YDG + D+WS             PF  +N+ ++  ++ + +Y  P
Sbjct:  163 QDVHVGKYKLLKTIGKGNFAKVKLAKHVITGHEVAIKIIDKTALNPSSL-QKLFREVKIMKQLDHPNIVKLYQVMETEQTLYLVLEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYLHSKNIIHRDLKAENLLLDQDMNIKIADFGFS---NTFSLGNKLDTFCGSPPYAAPELFSGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIP 387          

BLAST of DY262745 vs. ExPASy Swiss-Prot
Match: PAR1_CAEBR (Serine/threonine-protein kinase par-1 OS=Caenorhabditis briggsae GN=par-1 PE=3 SV=1)

HSP 1 Score: 179.104 bits (453), Expect = 4.110e-44
Identity = 88/229 (38.43%), Postives = 142/229 (62.01%), Query Frame = 2

Query:  191 RNILFGKYEMGRMLGQGTFAKVYYGKNLVTQESVAIKVINKDQVKKQGLMEQIKREISVMRLVKHPNIVELKEVMATKTKVFFVIEYVKGGELFAK-VLKGKLKEESARKYFQQLISAVDFCHSRGVYHRDLKPENLLLDENGNLKVSDFGLSALPEQLWNDGLLHTQCGTPAYVAPEVLRKKGYDGAKSDIWSCXXXXXXXXXXXXPFQNENIMKMYRKIFKAEYEFP 874
            +++  GKY++ + +G+G FAKV   K+++T   VAIK+I+K  +    L +++ RE+ +M+ + HPNIV+L +VM T+  ++ V+EY  GGE+F   V  G++KE+ AR  F+Q++SAV + HS+ + HRDLK ENLLLD++ N+K++DFG S           L T CG+P Y APE+   K YDG + D+WS             PF  +N+ ++  ++ + +Y  P
Sbjct:  121 QDVHVGKYKLLKTIGKGNFAKVKLAKHVITGHEVAIKIIDKTALNPSSL-QKLFREVKIMKQLDHPNIVKLYQVMETEQTLYLVLEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYLHSKNIIHRDLKAENLLLDQDMNIKIADFGFS---NTFSLGNKLDTFCGSPPYAAPELFSGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIP 345          

BLAST of DY262745 vs. ExPASy Swiss-Prot
Match: MARK1_RAT (Serine/threonine-protein kinase MARK1 OS=Rattus norvegicus GN=Mark1 PE=1 SV=1)

HSP 1 Score: 179.104 bits (453), Expect = 4.110e-44
Identity = 86/224 (38.39%), Postives = 140/224 (62.50%), Query Frame = 2

Query:  206 GKYEMGRMLGQGTFAKVYYGKNLVTQESVAIKVINKDQVKKQGLMEQIKREISVMRLVKHPNIVELKEVMATKTKVFFVIEYVKGGELFAK-VLKGKLKEESARKYFQQLISAVDFCHSRGVYHRDLKPENLLLDENGNLKVSDFGLSALPEQLWNDGLLHTQCGTPAYVAPEVLRKKGYDGAKSDIWSCXXXXXXXXXXXXPFQNENIMKMYRKIFKAEYEFP 874
            G Y + + +G+G FAKV   ++++T   VA+K+I+K Q+    L +++ RE+ +M+++ HPNIV+L EV+ T+  ++ V+EY  GGE+F   V  G++KE+ AR  F+Q++SAV +CH + + HRDLK ENLLLD + N+K++DFG S    +      L T CG+P Y APE+ + K YDG + D+WS             PF  +N+ ++  ++ + +Y  P
Sbjct:   58 GNYRLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPTSL-QKLFREVRIMKILNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKCIVHRDLKAENLLLDADMNIKIADFGFS---NEFTVGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRVP 277          

BLAST of DY262745 vs. ExPASy Swiss-Prot
Match: MARK1_MOUSE (Serine/threonine-protein kinase MARK1 OS=Mus musculus GN=Mark1 PE=1 SV=1)

HSP 1 Score: 179.104 bits (453), Expect = 4.110e-44
Identity = 86/224 (38.39%), Postives = 140/224 (62.50%), Query Frame = 2

Query:  206 GKYEMGRMLGQGTFAKVYYGKNLVTQESVAIKVINKDQVKKQGLMEQIKREISVMRLVKHPNIVELKEVMATKTKVFFVIEYVKGGELFAK-VLKGKLKEESARKYFQQLISAVDFCHSRGVYHRDLKPENLLLDENGNLKVSDFGLSALPEQLWNDGLLHTQCGTPAYVAPEVLRKKGYDGAKSDIWSCXXXXXXXXXXXXPFQNENIMKMYRKIFKAEYEFP 874
            G Y + + +G+G FAKV   ++++T   VA+K+I+K Q+    L +++ RE+ +M+++ HPNIV+L EV+ T+  ++ V+EY  GGE+F   V  G++KE+ AR  F+Q++SAV +CH + + HRDLK ENLLLD + N+K++DFG S    +      L T CG+P Y APE+ + K YDG + D+WS             PF  +N+ ++  ++ + +Y  P
Sbjct:   58 GNYRLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPTSL-QKLFREVRIMKILNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKCIVHRDLKAENLLLDADMNIKIADFGFS---NEFTVGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRVP 277          

BLAST of DY262745 vs. ExPASy Swiss-Prot
Match: MARK1_HUMAN (Serine/threonine-protein kinase MARK1 OS=Homo sapiens GN=MARK1 PE=1 SV=2)

HSP 1 Score: 179.104 bits (453), Expect = 4.110e-44
Identity = 86/224 (38.39%), Postives = 140/224 (62.50%), Query Frame = 2

Query:  206 GKYEMGRMLGQGTFAKVYYGKNLVTQESVAIKVINKDQVKKQGLMEQIKREISVMRLVKHPNIVELKEVMATKTKVFFVIEYVKGGELFAK-VLKGKLKEESARKYFQQLISAVDFCHSRGVYHRDLKPENLLLDENGNLKVSDFGLSALPEQLWNDGLLHTQCGTPAYVAPEVLRKKGYDGAKSDIWSCXXXXXXXXXXXXPFQNENIMKMYRKIFKAEYEFP 874
            G Y + + +G+G FAKV   ++++T   VA+K+I+K Q+    L +++ RE+ +M+++ HPNIV+L EV+ T+  ++ V+EY  GGE+F   V  G++KE+ AR  F+Q++SAV +CH + + HRDLK ENLLLD + N+K++DFG S    +      L T CG+P Y APE+ + K YDG + D+WS             PF  +N+ ++  ++ + +Y  P
Sbjct:   58 GNYRLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPTSL-QKLFREVRIMKILNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKYIVHRDLKAENLLLDGDMNIKIADFGFS---NEFTVGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIP 277          

BLAST of DY262745 vs. ExPASy Swiss-Prot
Match: MRKC_DICDI (Probable serine/threonine-protein kinase MARK-C OS=Dictyostelium discoideum GN=mrkC PE=3 SV=1)

HSP 1 Score: 178.333 bits (451), Expect = 7.011e-44
Identity = 94/227 (41.41%), Postives = 142/227 (62.56%), Query Frame = 2

Query:  206 GKYEMGRMLGQGTFAKVYYGKNLVTQESVAIKVINKDQVKKQGLMEQIKREISVMRLVKHPNIVELKEVMATKTK---VFFVIEYVKGGELFAKVLKGK-LKEESARKYFQQLISAVDFCHSRGVYHRDLKPENLLLDENGNLKVSDFGLSALPEQLWNDGLLHTQCGTPAYVAPEVLRKKGYDGAKSDIWSCXXXXXXXXXXXXPFQNENIMKMYRKIFKAEYEFP 874
            G YE+G+ LG GTF KV  G N+ T+E+VAIK I  +++  +   E   REI +M+L+ HPNIV+L +V+  + +    + ++EYV GGELF  ++  + +KE+ ARK+F+Q+ISA+++CH+  + HRDLKPENLLLD NG++K+SDFGLS     +    LL + CG+P Y APE+L+ + Y G   DIWS             P++ ++  ++        YE P
Sbjct:   44 GSYEVGKTLGNGTFGKVKLGTNICTKENVAIKFIKNNKLSGKQ-KETCFREIDIMKLLDHPNIVKLLDVVDKREEEGTTYLIVEYVSGGELFDYIVAREYIKEKEARKFFRQMISAIEYCHANLIVHRDLKPENLLLDSNGDIKISDFGLS---NNIQPGKLLESFCGSPLYAAPEILKAEKYLGPPVDIWSLGVIMYAVLCGNLPWEGDSQAEISFNSVHGNYEDP 266          

BLAST of DY262745 vs. ExPASy Swiss-Prot
Match: MARK4_MOUSE (MAP/microtubule affinity-regulating kinase 4 OS=Mus musculus GN=Mark4 PE=1 SV=1)

HSP 1 Score: 177.178 bits (448), Expect = 1.562e-43
Identity = 87/224 (38.84%), Postives = 137/224 (61.16%), Query Frame = 2

Query:  206 GKYEMGRMLGQGTFAKVYYGKNLVTQESVAIKVINKDQVKKQGLMEQIKREISVMRLVKHPNIVELKEVMATKTKVFFVIEYVKGGELFAKVLK-GKLKEESARKYFQQLISAVDFCHSRGVYHRDLKPENLLLDENGNLKVSDFGLSALPEQLWNDGLLHTQCGTPAYVAPEVLRKKGYDGAKSDIWSCXXXXXXXXXXXXPFQNENIMKMYRKIFKAEYEFP 874
            G Y + R +G+G FAKV   ++++T   VAIK+I+K Q+    L +++ RE+ +M+ + HPNIV+L EV+ T+  ++ V+EY   GE+F  ++  G++KE+ AR  F+Q++SAV +CH + + HRDLK ENLLLD   N+K++DFG S    +      L T CG+P Y APE+ + K YDG + DIWS             PF   N+ ++  ++ + +Y  P
Sbjct:   57 GNYRLLRTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPSSL-QKLFREVRIMKGLNHPNIVKLFEVIETEKTLYLVMEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAVHYCHQKNIVHRDLKAENLLLDAEANIKIADFGFS---NEFTLGSKLDTFCGSPPYAAPELFQGKKYDGPEVDIWSLGVILYTLVSGSLPFDGHNLKELRERVLRGKYRVP 276          

BLAST of DY262745 vs. ExPASy Swiss-Prot
Match: MARK4_HUMAN (MAP/microtubule affinity-regulating kinase 4 OS=Homo sapiens GN=MARK4 PE=1 SV=1)

HSP 1 Score: 177.178 bits (448), Expect = 1.562e-43
Identity = 87/224 (38.84%), Postives = 137/224 (61.16%), Query Frame = 2

Query:  206 GKYEMGRMLGQGTFAKVYYGKNLVTQESVAIKVINKDQVKKQGLMEQIKREISVMRLVKHPNIVELKEVMATKTKVFFVIEYVKGGELFAKVLK-GKLKEESARKYFQQLISAVDFCHSRGVYHRDLKPENLLLDENGNLKVSDFGLSALPEQLWNDGLLHTQCGTPAYVAPEVLRKKGYDGAKSDIWSCXXXXXXXXXXXXPFQNENIMKMYRKIFKAEYEFP 874
            G Y + R +G+G FAKV   ++++T   VAIK+I+K Q+    L +++ RE+ +M+ + HPNIV+L EV+ T+  ++ V+EY   GE+F  ++  G++KE+ AR  F+Q++SAV +CH + + HRDLK ENLLLD   N+K++DFG S    +      L T CG+P Y APE+ + K YDG + DIWS             PF   N+ ++  ++ + +Y  P
Sbjct:   57 GNYRLLRTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPSSL-QKLFREVRIMKGLNHPNIVKLFEVIETEKTLYLVMEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAVHYCHQKNIVHRDLKAENLLLDAEANIKIADFGFS---NEFTLGSKLDTFCGSPPYAAPELFQGKKYDGPEVDIWSLGVILYTLVSGSLPFDGHNLKELRERVLRGKYRVP 276