FC917648

BLAST of FC917648 vs. ExPASy Swiss-Prot
Match: GBA2_HUMAN (Non-lysosomal glucosylceramidase OS=Homo sapiens GN=GBA2 PE=1 SV=2)

HSP 1 Score: 280.796 bits (717), Expect = 7.527e-75
Identity = 144/312 (46.15%), Postives = 186/312 (59.62%), Query Frame = 2

Query:    2 YNTYDVHFYSSFALVMLFPKLELSIQRDFAAAVMMHDPGTMKIMSDGKWVARKFLGAVPHDIGL--DDPWFEINSYNLFNSSRWKDLNSKFVLQVYRDFVATGDKTFARAVWPSVYIAMAYMEQFDKDGDGMIENEGFPDQTYDAWSANGVSAYCGGLWVXXXXXXXXXXNDVGDHASASYFWVRYQKAKAVYDS-LWNGSYFNYDNSDGSSSTSIQADQLAGQWYARACGL----LPIADEAKVKKALTKIYDFNVLKVKGGMCGAMNGMQPDGRIDMSGLQAREIWPGVTYGLAASMIQEEMVDMAFQTA 916
            YNTYDVHFY+SFAL+ML+PKLELS+Q D A A +  D    + +  G     K    +PHDIG   D+PW  +N+Y + +++ WKDLN KFVLQVYRD+  TGD+ F + +WP     M    +FDKD DG+IEN G+ DQTYD W   G SAYCGGLW+             G       F     + +  Y+  LWNG Y+NYD+S    S S+ +DQ AGQW+ +ACGL      +     V +AL  I++ NV    GG  GA+NGMQP G  D S +Q+ E+W GV YGLAA+MIQE +    FQTA
Sbjct:  534 YNTYDVHFYASFALIMLWPKLELSLQYDMALATLREDLTRRRYLMSGVMAPVKRRNVIPHDIGDPDDEPWLRVNAYLIHDTADWKDLNLKFVLQVYRDYYLTGDQNFLKDMWPVCLAVMESEMKFDKDHDGLIENGGYADQTYDGWVTTGPSAYCGGLWLAAVAVMVQMAALCGAQDIQDKFSSILSRGQEAYERLLWNGRYYNYDSSSRPQSRSVMSDQCAGQWFLKACGLGEGDTEVFPTQHVVRALQTIFELNVQAFAGGAMGAVNGMQPHGVPDKSSVQSDEVWVGVVYGLAATMIQEGLTWEGFQTA 845          

BLAST of FC917648 vs. ExPASy Swiss-Prot
Match: GBA2_RAT (Non-lysosomal glucosylceramidase OS=Rattus norvegicus GN=Gba2 PE=2 SV=2)

HSP 1 Score: 277.715 bits (709), Expect = 6.372e-74
Identity = 148/316 (46.84%), Postives = 188/316 (59.49%), Query Frame = 2

Query:    2 YNTYDVHFYSSFALVMLFPKLELSIQRDFAAAVMMHDPGTMKIMSDGKWVARKFLGAVPHDIGL--DDPWFEINSYNLFNSSRWKDLNSKFVLQVYRDFVATGDKTFARAVWPSVYIAMAYMEQFDKDGDGMIENEGFPDQTYDAWSANGVSAYCGGLW-----VXXXXXXXXXXNDVGDHASASYFWVRYQKAKAVYDSLWNGSYFNYDNSDGSSSTSIQADQLAGQWYARACGL----LPIADEAKVKKALTKIYDFNVLKVKGGMCGAMNGMQPDGRIDMSGLQAREIWPGVTYGLAASMIQEEMVDMAFQTA 916
            YNTYDVHFY+SFALVML+PKLELS+Q D A A    D    + +  G     K    +PHDIG   D+PW  +N+Y + +++ WKDLN KFVLQVYRD+  TGD+ F + +WP     M    +FDKD DG+IEN G+ DQTYD W   G SAYCGGLW     V           DV D  S+    +  +  +A    LWNG Y+NYD+S    S S+ +DQ AGQW+ RACGL      +     V +AL  I++ NV    GG  GA+NGMQP G  D S +Q+ E+W GV YGLAA+MIQE +    F+TA
Sbjct:  525 YNTYDVHFYASFALVMLWPKLELSLQYDMALATFKEDLTRRRYLMSGVVAPVKRRNVIPHDIGDPDDEPWLRVNAYLIHDTADWKDLNLKFVLQVYRDYYLTGDQGFLKDMWPVCLAVMESEMKFDKDQDGLIENGGYADQTYDGWVTTGPSAYCGGLWLAAVAVMVQMAVLCGAQDVQDKFSS----ILCRGREAYERLLWNGRYYNYDSSSQPQSRSVMSDQCAGQWFLRACGLGEGDTEVFPTLHVVRALKTIFELNVQAFAGGAMGAVNGMQPHGVPDRSSVQSDEVWVGVVYGLAATMIQEGLTWEGFRTA 836          

BLAST of FC917648 vs. ExPASy Swiss-Prot
Match: GBA2_MOUSE (Non-lysosomal glucosylceramidase OS=Mus musculus GN=Gba2 PE=2 SV=2)

HSP 1 Score: 276.944 bits (707), Expect = 1.087e-73
Identity = 145/312 (46.47%), Postives = 185/312 (59.29%), Query Frame = 2

Query:    2 YNTYDVHFYSSFALVMLFPKLELSIQRDFAAAVMMHDPGTMKIMSDGKWVARKFLGAVPHDIGL--DDPWFEINSYNLFNSSRWKDLNSKFVLQVYRDFVATGDKTFARAVWPSVYIAMAYMEQFDKDGDGMIENEGFPDQTYDAWSANGVSAYCGGLWVXXXXXXXXXXNDVGDHASASYFWVRYQKAKAVYDS-LWNGSYFNYDNSDGSSSTSIQADQLAGQWYARACGL----LPIADEAKVKKALTKIYDFNVLKVKGGMCGAMNGMQPDGRIDMSGLQAREIWPGVTYGLAASMIQEEMVDMAFQTA 916
            YNTYDVHFY+SFALVML+PKLELS+Q D A A +  D    + +  G     K    +PHDIG   D+PW  +N+Y + +++ WKDLN KFVLQ+YRD+  TGD+ F   +WP     M    +FDKD DG+IEN G+ DQTYDAW   G SAYCGGLW+             G       F     + +  Y+  LWNG Y+NYD+S    S SI +DQ AGQW+ RACGL      +     V +AL  I++ NV    GG  GA+NGM P G  D S +Q+ E+W GV YGLAA+MIQE +    F+TA
Sbjct:  525 YNTYDVHFYASFALVMLWPKLELSLQYDMALATLKEDLTRRRYLMSGVVAPVKRRNVIPHDIGDPDDEPWLRVNAYLIHDTADWKDLNLKFVLQIYRDYYLTGDQGFLEDMWPVCLAVMESEMKFDKDQDGLIENGGYADQTYDAWVTTGPSAYCGGLWLAAVAVMVQMAVLCGAQDVQERFASILCRGREAYERLLWNGRYYNYDSSSHPQSRSIMSDQCAGQWFLRACGLGEGDTEVFPTLHVVRALQTIFELNVQAFAGGAMGAVNGMHPHGVPDRSSVQSDEVWVGVVYGLAATMIQEGLTWEGFRTA 836          

BLAST of FC917648 vs. ExPASy Swiss-Prot
Match: C3390_DROME (Non-lysosomal glucosylceramidase OS=Drosophila melanogaster GN=CG33090 PE=1 SV=1)

HSP 1 Score: 152.525 bits (384), Expect = 3.092e-36
Identity = 85/210 (40.48%), Postives = 114/210 (54.29%), Query Frame = 2

Query:  314 FARAVWPSVYIAMAYMEQFDKDGDGMIENEGFPDQTYDAWSANGVSAYCGGLWVXXXXXXXXXXNDVGDHASASYFWVRYQKAK-AVYDSLWNGSYFNYDNSDGSSSTSIQADQLAGQWYARACGL-LPIADEAKVKKALTKIYDFNVLKVKGGMCGAMNGM-------QPDGRIDMSGLQAREIWPGVTYGLAASMIQEEMVDMAFQTA 916
            + +A++ S    M    ++DKD DG+IEN   PDQTYD+W  +G SAYC GLW+            +        +    +K K ++ + LWNGSY+ +D S     T I ADQL G WY ++CG    I  +  V+ AL +IYD NV+    G  GA NG           G +D S +QA E+WPGV Y LAA+MIQE M + AFQTA
Sbjct:  687 YLKAMYASCKAIMERTIEYDKDNDGLIENTKMPDQTYDSWVMDGPSAYCSGLWLAALQAMSAMATILDQPNDCLRYQDILEKGKRSLEEKLWNGSYYRFDLSHSHRDT-IMADQLCGHWYLKSCGFDYEIYPKENVRTALKRIYDNNVMGFHEGNIGAANGFIANASEPTKPGHVDNSNIQAEEVWPGVVYALAATMIQEGMFEEAFQTA 895          

HSP 2 Score: 104.76 bits (260), Expect = 7.393e-22
Identity = 54/124 (43.55%), Postives = 80/124 (64.52%), Query Frame = 2

Query:    2 YNTYDVHFYSSFALVMLFPKLELSIQRDFAAAVMMHDPGTMKIMSDGKWVARKFLGAVPHDIGLDD--PWFEINSYNLFNSSRWKDLNSKFVLQVYRDFVATGDKTFARAVWPSVYIAMAYMEQ 367
            YNTYDVHFY+S AL  L+P L++S+Q DF  A+      T K++ DGK + RK    VPHD+G  D  P+  IN YN+ + + WKDLN+KFVLQVYRD+    +   A++   S + ++ ++++
Sbjct:  518 YNTYDVHFYASPALAHLWPNLQVSLQYDFKDAIAAELNDTRKMLYDGKVMPRKVKNCVPHDLGDPDEEPFTLINCYNIHDVNDWKDLNTKFVLQVYRDYYVLNELAQAQSDNASKFSSIEFIDK 641