FC923647

BLAST of FC923647 vs. ExPASy Swiss-Prot
Match: ALDR_MOUSE (Aldose reductase OS=Mus musculus GN=Akr1b1 PE=1 SV=3)

HSP 1 Score: 197.978 bits (502), Expect = 4.333e-50
Identity = 104/222 (46.85%), Postives = 135/222 (60.81%), Query Frame = 2

Query:   59 YFELNNGAKMPPIGLGTWQAQHGVVAEAIAIAIKQAGYRHIDCAYFYGNEKEIGTELKKLFEDGVIKREDLWITSKLWCCDHAPEDVPKAMDRTLQDLQIDYVDLYLVHWPVRTKKG--FISLNPEDLLQP---DIPSTWKAMEALYDSGKARAIGVSNFSVKKLQDLLKV--ARVTPAVNQVECHPGWHQEKLHEFCKSKGIHVXXXXXXXXXXXXWFKSD 703
            + ELNNG KMP +GLGTW++  G V EA+ +AI   GYRHIDCA  Y NEKE+G  L++  ++ V+KR+DL+I SKLWC  H    V  A  +TL DLQ+DY+DLYL+HWP   K G  +  L+    + P   D   TW AME L D G  + IGVSNF+  +++ +L     +  PAVNQ+ECHP   QEKL E+C SKGI V            W K +
Sbjct:    4 HLELNNGTKMPTLGLGTWKSPPGQVTEAVKVAI-DLGYRHIDCAQVYQNEKEVGVALQEKLKEQVVKRQDLFIVSKLWCTFHDKSMVKGAFQKTLSDLQLDYLDLYLIHWPTGFKPGPDYFPLDASGNVIPSDTDFVDTWTAMEQLVDEGLVKTIGVSNFNPLQIERILNKPGLKYKPAVNQIECHPYLTQEKLIEYCHSKGIVVTAYSPLGSPDRPWAKPE 224          

BLAST of FC923647 vs. ExPASy Swiss-Prot
Match: ALDR_RAT (Aldose reductase OS=Rattus norvegicus GN=Akr1b1 PE=1 SV=3)

HSP 1 Score: 197.208 bits (500), Expect = 7.390e-50
Identity = 104/222 (46.85%), Postives = 135/222 (60.81%), Query Frame = 2

Query:   59 YFELNNGAKMPPIGLGTWQAQHGVVAEAIAIAIKQAGYRHIDCAYFYGNEKEIGTELKKLFEDGVIKREDLWITSKLWCCDHAPEDVPKAMDRTLQDLQIDYVDLYLVHWPVRTKKG--FISLNPEDLLQP---DIPSTWKAMEALYDSGKARAIGVSNFSVKKLQDLLKV--ARVTPAVNQVECHPGWHQEKLHEFCKSKGIHVXXXXXXXXXXXXWFKSD 703
            + ELNNG KMP +GLGTW++  G V EA+ +AI   GYRHIDCA  Y NEKE+G  L++  ++ V+KR+DL+I SKLWC  H    V  A  +TL DLQ+DY+DLYL+HWP   K G  +  L+    + P   D   TW AME L D G  +AIGVSNF+  +++ +L     +  PAVNQ+ECHP   QEKL E+C  KGI V            W K +
Sbjct:    4 HLELNNGTKMPTLGLGTWKSPPGQVTEAVKVAIDM-GYRHIDCAQVYQNEKEVGVALQEKLKEQVVKRQDLFIVSKLWCTFHDQSMVKGACQKTLSDLQLDYLDLYLIHWPTGFKPGPDYFPLDASGNVIPSDTDFVDTWTAMEQLVDEGLVKAIGVSNFNPLQIERILNKPGLKYKPAVNQIECHPYLTQEKLIEYCHCKGIVVTAYSPLGSPDRPWAKPE 224          

BLAST of FC923647 vs. ExPASy Swiss-Prot
Match: AK1A1_XENLA (Alcohol dehydrogenase [NADP+] OS=Xenopus laevis GN=akr1a1 PE=2 SV=1)

HSP 1 Score: 192.586 bits (488), Expect = 1.820e-48
Identity = 99/205 (48.29%), Postives = 139/205 (67.80%), Query Frame = 2

Query:   50 NVQYFELNNGAKMPPIGLGTWQAQHGVVAEAIAIAIKQAGYRHIDCAYFYGNEKEIGTELKK-LFEDGVIKREDLWITSKLWCCDHAPEDVPKAMDRTLQDLQIDYVDLYLVHWPVRTKKG--FISLNPEDLLQPDIPS---TWKAMEALYDSGKARAIGVSNFSVKKLQDLLKVARVTPAVNQVECHPGWHQEKLHEFCKSKGI 646
            +V+Y  L  G KMP IGLGTW++  G V +A+  A+   GYRHIDCA+ YGNE E+G  +K+ +  D  +KRE++++TSKLW   H P+DV  A+ +TLQ+LQ+DY+DLYL+HWP   K+G      NP+  +Q D+     TWKAME L + G A+AIG+SNF+ +++ D+L +A V PAV QVECHP   Q +L   C+S G+
Sbjct:    4 SVEYETLYTGQKMPLIGLGTWKSAPGQVKDAVKYALG-VGYRHIDCAFVYGNETEVGEAIKESVGPDKGLKREEVFVTSKLWNNKHHPDDVECALRKTLQELQLDYLDLYLMHWPYAFKRGDQVFPQNPDGSVQYDLTDYKDTWKAMEKLVEKGLAKAIGLSNFNKRQMDDILSIATVKPAVLQVECHPYLAQNELIACCRSHGL 207          

BLAST of FC923647 vs. ExPASy Swiss-Prot
Match: ALDR_HORVU (Aldose reductase OS=Hordeum vulgare PE=1 SV=1)

HSP 1 Score: 192.2 bits (487), Expect = 2.377e-48
Identity = 98/200 (49.00%), Postives = 132/200 (66.00%), Query Frame = 2

Query:   59 YFELNNGAKMPPIGLGTWQAQHGVVAEAIAIAIKQAGYRHIDCAYFYGNEKEIGTELKKLFEDGVIKREDLWITSKLWCCDHAPEDVPKAMDRTLQDLQIDYVDLYLVHWPVRTKKGFISLNPE--DLLQPDIPSTWKAMEALYDSGKARAIGVSNFSVKKLQDLLKVARVTPAVNQVECHPGWHQEKLHEFCKSKGIHV 652
            +F L +G  MP +GLGTW+A     A ++  AI +AGYRH+D A  YG EKE+G  LK   E G I R+DL++TSK+WC + APE V  A++ TL+DLQ+DY+DLY +HWP R K G   + PE  ++L+ D+   WK ME L   G  + IGV N++V KL  LL+ A++ PAV Q+E HPGW  +K+ E CK  GIHV
Sbjct:   15 HFVLKSGHAMPAVGLGTWRAGSDT-AHSVRTAITEAGYRHVDTAAEYGVEKEVGKGLKAAMEAG-IDRKDLFVTSKIWCTNLAPERVRPALENTLKDLQLDYIDLYHIHWPFRLKDG-AHMPPEAGEVLEFDMEGVWKEMENLVKDGLVKDIGVCNYTVTKLNRLLRSAKIPPAVCQMEMHPGWKNDKIFEACKKHGIHV 211          

BLAST of FC923647 vs. ExPASy Swiss-Prot
Match: ALDR_HUMAN (Aldose reductase OS=Homo sapiens GN=AKR1B1 PE=1 SV=3)

HSP 1 Score: 191.815 bits (486), Expect = 3.105e-48
Identity = 101/219 (46.12%), Postives = 136/219 (62.10%), Query Frame = 2

Query:   68 LNNGAKMPPIGLGTWQAQHGVVAEAIAIAIKQAGYRHIDCAYFYGNEKEIGTELKKLFEDGVIKREDLWITSKLWCCDHAPEDVPKAMDRTLQDLQIDYVDLYLVHWPVRTKKG--FISLNPEDLLQP---DIPSTWKAMEALYDSGKARAIGVSNFSVKKLQDLLKV--ARVTPAVNQVECHPGWHQEKLHEFCKSKGIHVXXXXXXXXXXXXWFKSD 703
            LNNGAKMP +GLGTW++  G V EA+ +AI   GYRHIDCA+ Y NE E+G  +++   + V+KRE+L+I SKLWC  H    V  A  +TL DL++DY+DLYL+HWP   K G  F  L+    + P   +I  TW AME L D G  +AIG+SNF+  +++ +L     +  PAVNQ+ECHP   QEKL ++C+SKGI V            W K +
Sbjct:    7 LNNGAKMPILGLGTWKSPPGQVTEAVKVAI-DVGYRHIDCAHVYQNENEVGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPE 224          

BLAST of FC923647 vs. ExPASy Swiss-Prot
Match: ALDR_BOVIN (Aldose reductase OS=Bos taurus GN=AKR1B1 PE=1 SV=1)

HSP 1 Score: 191.045 bits (484), Expect = 5.296e-48
Identity = 102/219 (46.58%), Postives = 134/219 (61.19%), Query Frame = 2

Query:   68 LNNGAKMPPIGLGTWQAQHGVVAEAIAIAIKQAGYRHIDCAYFYGNEKEIGTELKKLFEDGVIKREDLWITSKLWCCDHAPEDVPKAMDRTLQDLQIDYVDLYLVHWPVRTKKG--FISLNPEDLLQP---DIPSTWKAMEALYDSGKARAIGVSNFSVKKLQDLLKV--ARVTPAVNQVECHPGWHQEKLHEFCKSKGIHVXXXXXXXXXXXXWFKSD 703
            L  GAKMP +GLGTW++  G V EA+ +AI   GYRHIDCA+ Y NE E+G  L+   ++ V+KREDL+I SKLWC  H  + V  A  +TL DL++DY+DLYL+HWP   K G  F  L+ +  + P   D   TW AME L D G  +AIGVSNF+  +++ +L     +  PAVNQ+ECHP   QEKL ++C SKGI V            W K +
Sbjct:    6 LYTGAKMPILGLGTWKSPPGKVTEAVKVAI-DLGYRHIDCAHVYQNENEVGLALQAKLQEQVVKREDLFIVSKLWCTYHDKDLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKDFFPLDEDGNVIPSEKDFVDTWTAMEELVDEGLVKAIGVSNFNHLQVEKILNKPGLKYKPAVNQIECHPYLTQEKLIQYCNSKGIVVTAYSPLGSPDRPWAKPE 223          

BLAST of FC923647 vs. ExPASy Swiss-Prot
Match: ALDR_PIG (Aldose reductase OS=Sus scrofa GN=AKR1B1 PE=1 SV=2)

HSP 1 Score: 189.119 bits (479), Expect = 2.013e-47
Identity = 103/219 (47.03%), Postives = 134/219 (61.19%), Query Frame = 2

Query:   68 LNNGAKMPPIGLGTWQAQHGVVAEAIAIAIKQAGYRHIDCAYFYGNEKEIGTELKKLFEDGVIKREDLWITSKLWCCDHAPEDVPKAMDRTLQDLQIDYVDLYLVHWPVRTKKGF--ISLNPEDLLQP---DIPSTWKAMEALYDSGKARAIGVSNFSVKKLQDLLKV--ARVTPAVNQVECHPGWHQEKLHEFCKSKGIHVXXXXXXXXXXXXWFKSD 703
            L  GAKMP +GLGTW++  G V EA+ +AI   GYRHIDCA+ Y NE E+G  L++  +  V+KREDL+I SKLWC DH    V  A   TL+DL++DY+DLYL+HWP   K G     L+ +  + P   D   TW+AME L D G  +AIGVSNF+  +++ +L     +  PAVNQ+E HP   QEKL E+CKSKGI V            W K +
Sbjct:    7 LYTGAKMPILGLGTWKSPPGKVTEAVKVAI-DLGYRHIDCAHVYQNENEVGLGLQEKLQGQVVKREDLFIVSKLWCTDHEKNLVKGACQTTLRDLKLDYLDLYLIHWPTGFKPGKDPFPLDGDGNVVPDESDFVETWEAMEELVDEGLVKAIGVSNFNHLQVEKILNKPGLKYKPAVNQIEVHPYLTQEKLIEYCKSKGIVVTAYSPLGSPDRPWAKPE 224          

BLAST of FC923647 vs. ExPASy Swiss-Prot
Match: ALDR_RABIT (Aldose reductase OS=Oryctolagus cuniculus GN=AKR1B1 PE=2 SV=3)

HSP 1 Score: 188.348 bits (477), Expect = 3.433e-47
Identity = 100/219 (45.66%), Postives = 134/219 (61.19%), Query Frame = 2

Query:   68 LNNGAKMPPIGLGTWQAQHGVVAEAIAIAIKQAGYRHIDCAYFYGNEKEIGTELKKLFEDGVIKREDLWITSKLWCCDHAPEDVPKAMDRTLQDLQIDYVDLYLVHWPVRTKKG--FISLNPEDLLQP---DIPSTWKAMEALYDSGKARAIGVSNFSVKKLQDLLKV--ARVTPAVNQVECHPGWHQEKLHEFCKSKGIHVXXXXXXXXXXXXWFKSD 703
            L NGAKMP +GLGTW++  G V EA+  AI   GYRHIDCA+ Y NE E+G  L++  ++ V+KRE+L+I SKLWC  H    V  A  +TL DL++DY+DLYL+HWP   K G  +  L+    + P   D   TW+AME L D G  ++IGVSNF+  +++ +L     +  PAVNQ+ECHP   QEKL ++C SKGI V            W K +
Sbjct:    7 LYNGAKMPILGLGTWKSPPGQVTEAVKTAI-DLGYRHIDCAHVYQNENEVGVALQEKLKEQVVKREELFIVSKLWCTSHDKSLVKGACQKTLNDLKLDYLDLYLIHWPTGFKHGSEYFPLDAAGNVIPSDTDFLDTWEAMEGLVDEGLVKSIGVSNFNHLQIERILNKPGLKYKPAVNQIECHPYLTQEKLIQYCHSKGIVVTAYSPLGSPDRPWAKPE 224          

BLAST of FC923647 vs. ExPASy Swiss-Prot
Match: AK1A1_CHICK (Alcohol dehydrogenase [NADP+] OS=Gallus gallus GN=AKR1A1 PE=2 SV=1)

HSP 1 Score: 188.348 bits (477), Expect = 3.433e-47
Identity = 102/226 (45.13%), Postives = 138/226 (61.06%), Query Frame = 2

Query:   59 YFELNNGAKMPPIGLGTWQAQHGVVAEAIAIAIKQAGYRHIDCAYFYGNEKEIGTELKKLF-EDGVIKREDLWITSKLWCCDHAPEDVPKAMDRTLQDLQIDYVDLYLVHWPVRTKKG--FISLNPEDLLQ---PDIPSTWKAMEALYDSGKARAIGVSNFSVKKLQDLLKVARVTPAVNQVECHPGWHQEKLHEFCKSKGIHVXXXXXXXXXXXXWFKSDVLKHP 718
            +  L NG K+P IGLGTW+++ G V EA+  A+   GYRH+DCA  Y NE EIG   ++    + VIKREDL++TSKLW   H PEDV  A+ +TL DL++DY+DLYL+HWP   ++G      NP+  ++    D   TWKAME L + G A+AIG+SNF+ +++ D+L VA V PAV QVECHP   Q +L   C+ +G+ V            W      KHP
Sbjct:    7 FVALYNGQKIPLIGLGTWKSEPGQVKEAVKYALS-VGYRHVDCAAAYSNEAEIGDAFQECVGPNKVIKREDLFVTSKLWNTKHHPEDVEPALRKTLADLKLDYLDLYLMHWPHAFERGDNLFPKNPDGTMRYDYTDYKDTWKAMEKLVEKGLAKAIGLSNFNSRQIDDVLSVATVKPAVLQVECHPYLAQNELIAHCQKRGLVVTAYSPLGSPDRMW------KHP 225          

BLAST of FC923647 vs. ExPASy Swiss-Prot
Match: YDG7_SCHPO (Uncharacterized oxidoreductase C26F1.07 OS=Schizosaccharomyces pombe GN=SPAC26F1.07 PE=2 SV=1)

HSP 1 Score: 187.193 bits (474), Expect = 7.648e-47
Identity = 102/214 (47.66%), Postives = 138/214 (64.49%), Query Frame = 2

Query:   26 EMDQIANDNVQYFELNNGAKMPPIGLGTWQAQHGVVAEAIAIAIKQAGYRHIDCAYFYGNEKEIGTELKKLFEDGVIKREDLWITSKLWCCDHAPEDVPKAMDRTLQDLQIDYVDLYLVHWPVRTKKG---FISLNPEDLL--QPDIPSTWKAMEALYDSGKARAIGVSNFSVKKLQDLLKVARVTPAVNQVECHPGWHQEKLHEFCKSKGIHV 652
            E     N    +F L +G+K+P +GLGTW+++      A+  A+ Q GYRHID A  YGNE E+G  +K   E GV  R+D+W+TSKLWC  HAPE VPKA+++TL+DL++DY+D YL+HWPV  K G   F      +L+  +  I  TWKAME L ++GK R IG+SNF+   L+ +LKVA+V PAV+Q+E HP   Q +  E  K  GIHV
Sbjct:    4 EQKYFENAQNVHFTLADGSKIPGLGLGTWRSEPNQTKNAVKTAL-QYGYRHIDAAAIYGNEDEVGDGIK---ESGV-PRKDIWVTSKLWCNAHAPEAVPKALEKTLKDLKLDYLDEYLIHWPVSFKTGEDKFPKDKDGNLIYEKNPIEETWKAMEKLLETGKVRHIGLSNFNDTNLERILKVAKVKPAVHQMELHPFLPQTEFVEKHKKLGIHV 212