CB293211

BLAST of CB293211 vs. ExPASy Swiss-Prot
Match: C72A1_CATRO (Secologanin synthase OS=Catharanthus roseus GN=CYP72A1 PE=2 SV=1)

HSP 1 Score: 132.109 bits (331), Expect = 3.814e-30
Identity = 82/279 (29.39%), Postives = 145/279 (51.97%), Query Frame = 3

Query:    9 GLSRSNGHCWAQQRKIVAPEFFMDKVKGMVGIMVESTQPLLRKWQDCVEAEDGVNADIRVDEDLREVSADVISRASFGSSNLRGKEIFAKLRSLQKAISN---QSFLFGATNFAGRFLAMKKHDNIGNLEKEIESLIWDTVKEREQQCAGAXXXXXXDLMQLILEGAVKD---QSLGKDSSKRF--IVDNCKNIYFAGHESTAVAASWCLMLLALHPEWQNHIRTELTQVCGDSLLDADSLPHLKTVTMVIQESLRLYPPAAFVSREALEDTQIGNIKI 821
            G+    G  W++ R+I++P F ++K+K M+         +L KW+   E +     DI    D+  +++DVIS+ +FGS+   G +IF  L+ L     +     ++ G +     +L  K++  +  + KEI  ++   + +R  +   A      DL+ ++LE  +++   Q   KD       +++ CK  YFAG E+T V  +W  +LL+ HPEWQ   R E+ Q  G +  + + L HLK V+M++ E LRLYPP   +++   +DT++G+  I
Sbjct:  144 GVGSFEGAKWSKHRRIISPAFTLEKLKSMLPAFAICYHDMLTKWEKIAEKQGSHEVDIFPTFDV--LTSDVISKVAFGSTYEEGGKIFRLLKELMDLTIDCMRDVYIPGWS-----YLPTKRNKRMKEINKEITDMLRFIINKR-MKALKAGEPGEDDLLGVLLESNIQEIQKQGNKKDGGMSINDVIEECKLFYFAGQETTGVLLTWTTILLSKHPEWQERAREEVLQAFGKNKPEFERLNHLKYVSMILYEVLRLYPPVIDLTKIVHKDTKLGSYTI 414          

BLAST of CB293211 vs. ExPASy Swiss-Prot
Match: CP4B1_HUMAN (Cytochrome P450 4B1 OS=Homo sapiens GN=CYP4B1 PE=1 SV=2)

HSP 1 Score: 96.6709 bits (239), Expect = 1.776e-19
Identity = 77/274 (28.10%), Postives = 127/274 (46.35%), Query Frame = 3

Query:    9 GLSRSNGHCWAQQRKIVAPEFFMDKVKGMVGIMVESTQPLLRKWQDCVEAEDGVNADIRVDEDLREVSADVISRASFGSSNL----RGKEIFAKLRSL-----QKAISNQ---SFLFGATNFAGRFL--AMKKHDNIGNLEKEIESLIWDTVKEREQQCAGAXXXXXXDLMQLILEGAVKDQSLGKDSSKRFIVDNCKNIYFAGHESTAVAASWCLMLLALHPEWQNHIRTELTQVCGD-SLLDADSLPHLKTVTMVIQESLRLYPPAAFVSRE 785
            GL    G  W Q RK++ P F  D +K  V +  EST+ +L KW++  +A +G + DI    D+  ++ + + + +FG  +     R    +  +  L     Q+ +S Q    F++  T    RFL      HD+   + +E ++ + D    ++ Q          D + ++L    +D     D+  R  VD      F GH++T    SW L  +AL+PE Q+  R E+ ++ GD      D L  +  +TM I+ES RLYPP   V R+
Sbjct:  125 GLLVLEGPKWLQHRKLLTPGFHYDVLKPYVAVFTESTRIMLDKWEE--KAREGKSFDIFC--DVGHMALNTLMKCTFGRGDTGLGHRDSSYYLAVSDLTLLMQQRLVSFQYHNDFIYWLTPHGRRFLRACQVAHDHTDQVIRERKAALQDEKVRKKIQ-----NRRHLDFLDILLGARDEDDIKLSDADLRAEVD---TFMFEGHDTTTSGISWFLYCMALYPEHQHRCREEVREILGDQDFFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQ 386          

BLAST of CB293211 vs. ExPASy Swiss-Prot
Match: CP4A5_RABIT (Cytochrome P450 4A5 OS=Oryctolagus cuniculus GN=CYP4A5 PE=2 SV=1)

HSP 1 Score: 95.9005 bits (237), Expect = 3.029e-19
Identity = 75/281 (26.69%), Postives = 131/281 (46.62%), Query Frame = 3

Query:    6 WGLSRSNGHCWAQQRKIVAPEFFMDKVKGMVGIMVESTQPLLRKWQDCVEAEDGVNADIRVDEDLREVSADVISRASF---GSSNLRGKE--------------IFAKLRSLQKAISNQSFLFGATNFAGRF---LAMKKHDNIGNLEKEIESLIWDTVKEREQQCAGAXXXXXXDLMQLILEGAVKDQSLGKDSSKRFIVDNCKNIYFAGHESTAVAASWCLMLLALHPEWQNHIRTELTQVCGD-SLLDADSLPHLKTVTMVIQESLRLYPPAAFVSRE 785
            +GL   NG  W Q R+++ P F  D +K  VG+MV+S Q +L KW+  V  +    + + V +D+  ++ D I + +F   GS  L  +               +FA++R+    I +QS      +  GR         H++   + ++ ++ +     ++E +          D + ++L   +++ S   D   R  VD      F GH++TA   SW    LA HPE Q+  R E+  + GD + +  + L  +   TM I+E++RLYPP   +SR+
Sbjct:  129 YGLLLLNGQPWFQHRRMLTPAFHYDILKPYVGLMVDSVQIMLDKWEQLVSQD----SSLEVFQDISLMTLDTIMKCAFSYQGSVQLDSRNSQSYIQAVGDLNNLVFARVRN----IFHQSDTIYRLSPEGRLSHRACQLAHEHTDRVIQQRKAQL-----QQEGELEKVRRKRRLDFLDVLLFAKMENGSSLSDQDLRAEVD---TFMFEGHDTTASGVSWIFYALATHPEHQHRCREEIQGLLGDGASITWEHLDQMPYTTMCIKEAMRLYPPVPAISRD 393          

BLAST of CB293211 vs. ExPASy Swiss-Prot
Match: CP4AC_RAT (Cytochrome P450 4A12 OS=Rattus norvegicus GN=Cyp4a12 PE=2 SV=2)

HSP 1 Score: 95.1301 bits (235), Expect = 5.167e-19
Identity = 73/277 (26.35%), Postives = 123/277 (44.40%), Query Frame = 3

Query:    6 WGLSRSNGHCWAQQRKIVAPEFFMDKVKGMVGIMVESTQPLLRKWQDCVEAEDGVNADIRVDEDLREVSADVISRASFGSSNLRGKEIFAKLRSLQKAI---SNQSFL--------------FGATNFAGRFLAMKKHDNIGNLEKEIESLIWDTVKEREQQCAGAXXXXXXDLMQLILEGAVKDQSLGKDSSKRFIVDNCKNIYFAGHESTAVAASWCLMLLALHPEWQNHIRTELTQVCGD-SLLDADSLPHLKTVTMVIQESLRLYPPAAFVSR 782
            +GL   NG  W Q R+++ P F  D +K  VGIM +S + +L KW+  V    G ++ + + + +  ++ D I + +F        ++  K +S  KA+   +N SF                 +     R      H++   + K  ++ + D     E++          D + ++L   +++ S   D   R  VD      F GH++TA   SW    LA +PE Q   R E+  + GD + +  D L  +   TM I+E+LR+YPP   VSR
Sbjct:  127 YGLLLLNGQTWFQHRRMLTPAFHYDTLKPYVGIMADSVRIMLDKWEQIV----GQDSTLEIFQHITLMTLDTIMKCAFSQEG--SVQLDRKYKSYIKAVEDLNNLSFFRIRNIFHQNDIIYSLSSNGRKARSAWQLAHEHTDQVIKSRKAQLQD-----EEELQKVKQKRRLDFLDILLFARIENGSSLSDKDLRAEVD---TFMFEGHDTTASGISWIFYALATNPEHQQGCRKEIQSLLGDGASITWDDLDKMPYTTMCIKEALRIYPPVTAVSR 389          

BLAST of CB293211 vs. ExPASy Swiss-Prot
Match: CP4X1_RAT (Cytochrome P450 4X1 OS=Rattus norvegicus GN=Cyp4x1 PE=2 SV=1)

HSP 1 Score: 94.3597 bits (233), Expect = 8.813e-19
Identity = 76/268 (28.36%), Postives = 126/268 (47.01%), Query Frame = 3

Query:    9 GLSRSNGHCWAQQRKIVAPEFFMDKVKGMVGIMVESTQPLLRKWQDCVEAEDGVNADIRVDEDLREVSADVISRASFGSSN---LRGK-EIFAKLR-SLQKAISNQSFLFGATNFAGRFLAMKKH--DNIGNLEKEI-ESLIWDTVKEREQQCAGAXXXXXXDLMQLILEGAVKDQSLGKDSSKRFIVDNCKNIYFAGHESTAVAASWCLMLLALHPEWQNHIRTELTQVCGD-SLLDADSLPHLKTVTMVIQESLRLYPPAAFVSRE 785
            GL   +G  W Q R ++ P F  D +K  V +M  S   +L KW+     ++     I V E +  ++ D+I + +FG      + G  E + K    L + IS++ + F   +     L+ K H    +G +  +  E +I D  K  + Q          + + ++L     D+    D+  R  V+      +AGH+++A + SW L  LAL+PE Q+  RTE+  + GD S +  + L  +   TM I+E+LRL PP   +SRE
Sbjct:  124 GLLNLDGPRWFQHRCLLTPAFHQDILKPCVDMMAHSVNMMLDKWEKTWTTQE---TTIEVFEHINLMTLDIIMKCAFGQETNCQINGTYESYVKATFELGEIISSRLYNFWHHHDIIFKLSPKGHCFQELGKVIHQCTEKIIQDRKKTLKDQVNQDDTQTSQNFLDIVLSAQAGDEKAFSDADLRSEVNT---FMWAGHDASAASISWLLYCLALNPEHQDRCRTEIRSILGDGSSITWEQLDEIPYTTMCIKETLRLIPPIPSISRE 385          

BLAST of CB293211 vs. ExPASy Swiss-Prot
Match: CP4AP_PIG (Cytochrome P450 4A25 OS=Sus scrofa GN=CYP4A25 PE=2 SV=1)

HSP 1 Score: 93.5893 bits (231), Expect = 1.503e-18
Identity = 80/278 (28.78%), Postives = 124/278 (44.60%), Query Frame = 3

Query:    9 GLSRSNGHCWAQQRKIVAPEFFMDKVKGMVGIMVESTQPLLRKWQDCVEAEDGVNADIRVDEDLREVSADVISRASF---GSSNLRG------------KEIFA---KLRSLQKAISNQSFLFGATNFAGRFLAMKKHDNIGNLEKEIESLIWDTVKEREQQCAGAXXXXXXDLMQLILEGAVKDQSLGKDSSKRFIVDNCKNIYFAGHESTAVAASWCLMLLALHPEWQNHIRTELTQVCGD-SLLDADSLPHLKTVTMVIQESLRLYPPAAFVSRE 785
            GL   NG  W Q+R+++ P F  D +K  VG+M +S Q +L KW+  V A+D     + +   +  ++ D I + +F   GS+   G            K +F+   K   LQ  I  +    G  N     +A +  D +  L K           +++ +          D + ++L   ++  +   D+  R  VD      F GH++TA   SW L  LA HPE Q   R E+  + GD + +  D L  +   TM I+E+LRLYPP   VSRE
Sbjct:  124 GLLLLNGQTWFQRRRMLTPAFHYDILKPYVGLMAKSVQVMLDKWEQLV-AQD---PRLEIVGPVSLMTLDTIMKCAFSHQGSAQTDGDSHSYIQAIWDLKNLFSIRTKSAFLQNDIIYRLSPEGRKNHRAARIAHQHTDRVIQLRK--------AQLQKQGEMENVRKKRHLDFLDILLLARMEKGNSLSDTDLRAEVD---TFMFEGHDTTASGISWILYALASHPEHQQRCREEIQGLLGDGTSITWDHLDQMPYTTMCIKEALRLYPPVPGVSRE 386          

BLAST of CB293211 vs. ExPASy Swiss-Prot
Match: CP4AO_PIG (Cytochrome P450 4A24 OS=Sus scrofa GN=CYP4A24 PE=2 SV=1)

HSP 1 Score: 93.5893 bits (231), Expect = 1.503e-18
Identity = 80/278 (28.78%), Postives = 124/278 (44.60%), Query Frame = 3

Query:    9 GLSRSNGHCWAQQRKIVAPEFFMDKVKGMVGIMVESTQPLLRKWQDCVEAEDGVNADIRVDEDLREVSADVISRASF---GSSNLRG------------KEIFA---KLRSLQKAISNQSFLFGATNFAGRFLAMKKHDNIGNLEKEIESLIWDTVKEREQQCAGAXXXXXXDLMQLILEGAVKDQSLGKDSSKRFIVDNCKNIYFAGHESTAVAASWCLMLLALHPEWQNHIRTELTQVCGD-SLLDADSLPHLKTVTMVIQESLRLYPPAAFVSRE 785
            GL   NG  W Q+R+++ P F  D +K  VG+M +S Q +L KW+  V A+D     + +   +  ++ D I + +F   GS+   G            K +F+   K   LQ  I  +    G  N     +A +  D +  L K           +++ +          D + ++L   ++  +   D+  R  VD      F GH++TA   SW L  LA HPE Q   R E+  + GD + +  D L  +   TM I+E+LRLYPP   VSRE
Sbjct:  124 GLLLLNGQTWFQRRRMLTPAFHYDILKPYVGLMAKSVQVMLDKWEQLV-AQD---PRLEIVGPVSLMTLDTIMKCAFSHQGSAQTDGDSHSYIQAIWDLKNLFSIRTKSAFLQNDIIYRLSPEGRKNHRAARIAHQHTDRVIQLRK--------AQLQKQGEMENVRKKRHLDFLDILLLARMEKGNSLSDTDLRAEVD---TFMFEGHDTTASGISWILYALASHPEHQQRCREEIQGLLGDGTSITWDHLDQMPYTTMCIKEALRLYPPVPGVSRE 386          

BLAST of CB293211 vs. ExPASy Swiss-Prot
Match: CP4AE_MOUSE (Cytochrome P450 4A14 OS=Mus musculus GN=Cyp4a14 PE=2 SV=1)

HSP 1 Score: 93.2041 bits (230), Expect = 1.963e-18
Identity = 74/271 (27.31%), Postives = 118/271 (43.54%), Query Frame = 3

Query:    6 WGLSRSNGHCWAQQRKIVAPEFFMDKVKGMVGIMVESTQPLLRKWQDCVEAEDGVNADIRVDEDLREVSADVISRASFGSSNLRGKEIFAKLRSLQKAISNQSFLFGATNFAGRFLAMKKHDNIGNLEKEIESLIWD----TVKER------EQQCAGAXXXXXXDLMQLILEGAVKDQSLGKDSSKRFIVDNCKNIYFAGHESTAVAASWCLMLLALHPEWQNHIRTELTQVCGD-SLLDADSLPHLKTVTMVIQESLRLYPPAAFVSRE 785
            +GL   NG  W Q R+++ P F  D +K  V IM +S   +L KW    E  DG +  + +   +  ++ D + + +F        +  +KL +      N    F   N   ++  +    + G L      +  +     +K R      E++   A      D + ++L   ++D++   D   R  VD      F GH++TA   SW    LA HPE Q   R E+  + GD + +  D L  +   TM I+E+LRLYPP   VSRE
Sbjct:  126 YGLLLLNGKKWFQHRRMLTPAFHYDILKPYVKIMADSVNIMLDKW----EKLDGQDHPLEIFHCVSLMTLDTVMKCAFSYQGSVQLDENSKLYTKAVEDLNNLTFFRLRNAFYKYNIIYNMSSDGRLSHHACQIAHEHTDGVIKMRKSQLQNEEELQKARKKRHLDFLDILLFARMEDRNSLSDEDLRAEVDT---FMFEGHDTTASGISWIFYALATHPEHQQRCREEVQSILGDGTSVTWDHLGQMPYTTMCIKEALRLYPPVISVSRE 389          

BLAST of CB293211 vs. ExPASy Swiss-Prot
Match: CP4AB_HUMAN (Cytochrome P450 4A11 OS=Homo sapiens GN=CYP4A11 PE=1 SV=1)

HSP 1 Score: 93.2041 bits (230), Expect = 1.963e-18
Identity = 75/280 (26.79%), Postives = 130/280 (46.43%), Query Frame = 3

Query:    6 WGLSRSNGHCWAQQRKIVAPEFFMDKVKGMVGIMVESTQPLLRKWQDCVEAEDGVNADIRVDEDLREVSADVISRASF---GSSNL-RGKEIFAKLRS---------LQKAISNQSFLFGATNFAGRF------LAMKKHDNIGNLEKEIESLIWDTVKEREQQCAGAXXXXXXDLMQLILEGAVKDQSLGKDSSKRFIVDNCKNIYFAGHESTAVAASWCLMLLALHPEWQNHIRTELTQVCGD-SLLDADSLPHLKTVTMVIQESLRLYPPAAFVSRE 785
            +GL   NG  W Q R+++ P F  D +K  VG+M +S + +L KW++ +    G ++ + V + +  ++ D I + +F   GS  + R  + + +  S         ++ A      ++  T+ AGR+      LA +  D +  L K           ++E +          D + ++L   +++ S+  D   R  VD      F GH++TA   SW L  LA HP+ Q   R E+  + GD + +  + L  +   TM I+E+LRLYPP   + RE
Sbjct:  129 YGLLLLNGQTWFQHRRMLTPAFHYDILKPYVGLMADSVRVMLDKWEELL----GQDSPLEVFQHVSLMTLDTIMKCAFSHQGSIQVDRNSQSYIQAISDLNNLVFSRVRNAFHQNDTIYSLTS-AGRWTHRACQLAHQHTDQVIQLRK--------AQLQKEGELEKIKRKRHLDFLDILLLAKMENGSILSDKDLRAEVD---TFMFEGHDTTASGISWILYALATHPKHQERCREEIHSLLGDGASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRE 392          

BLAST of CB293211 vs. ExPASy Swiss-Prot
Match: CP4AM_HUMAN (Cytochrome P450 4A22 OS=Homo sapiens GN=CYP4A22 PE=1 SV=1)

HSP 1 Score: 92.8189 bits (229), Expect = 2.564e-18
Identity = 75/280 (26.79%), Postives = 131/280 (46.79%), Query Frame = 3

Query:    6 WGLSRSNGHCWAQQRKIVAPEFFMDKVKGMVGIMVESTQPLLRKWQDCVEAEDGVNADIRVDEDLREVSADVISRASF---GSSNL-RGKEIFAKLRS---------LQKAISNQSFLFGATNFAGRF------LAMKKHDNIGNLEKEIESLIWDTVKEREQQCAGAXXXXXXDLMQLILEGAVKDQSLGKDSSKRFIVDNCKNIYFAGHESTAVAASWCLMLLALHPEWQNHIRTELTQVCGD-SLLDADSLPHLKTVTMVIQESLRLYPPAAFVSRE 785
            +GL   NG  W Q R+++ P F  D +K  VG+M +S + +L KW++ +    G ++ + V + +  ++ D I +++F   GS  + R  + + +  S         ++ A      ++  T+ AGR+      LA +  D +  L K           ++E +          D + ++L   +++ S+  D   R  VD      F GH++TA   SW L  LA HP+ Q   R E+  + GD + +  + L  +   TM I+E+LRLYPP   + RE
Sbjct:  129 YGLLLLNGQTWFQHRRMLTPAFHNDILKPYVGLMADSVRVMLDKWEELL----GQDSPLEVFQHVSLMTLDTIMKSAFSHQGSIQVDRNSQSYIQAISDLNSLVFCCMRNAFHENDTIYSLTS-AGRWTHRACQLAHQHTDQVIQLRK--------AQLQKEGELEKIKRKRHLDFLDILLLAKMENGSILSDKDLRAEVD---TFMFEGHDTTASGISWILYALATHPKHQERCREEIHGLLGDGASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRE 392