CK933373

BLAST of CK933373 vs. ExPASy Swiss-Prot
Match: DPYD_CAEEL (Dihydropyrimidine dehydrogenase [NADP+] OS=Caenorhabditis elegans GN=dpyd-1 PE=2 SV=2)

HSP 1 Score: 184.111 bits (466), Expect = 9.222e-46
Identity = 95/218 (43.58%), Postives = 135/218 (61.93%), Query Frame = 3

Query:  255 EPDLSITVNGLQMPNPFVIGSGPPGTNYTVMKRAFDEGWGAVVAKTVSLDAAKVINVTPRYARLRAGANGSAKGQIIG-----WENIELISDRPLETMLKEFKQLKALYPDRILIASIMEEYNKAAWEELIDRVEETGIDAIEVNFSCPHGMPERKMGAAVGQDCRLLEEVCGWINAKATVPVWAKMTPNITDITEPARVALRSGSEGASXXNTIMSV 893
            E D+S+ + G++  NPF + S PP T+  + +RAF++GWG ++ KT  LD   V NV+PR  R      GS  G + G     + NIELIS++  E  L+  ++LK  +P +I+IASIM  YNKA W EL  + EE G D +E+N SCPHGM E+ MG A GQ   +++E+C W+ A   +P + KMTPNITD+ E AR A   G+ G +  NT+ S+
Sbjct:  544 EVDISVDMCGVKFENPFGLASAPPTTSGPMCRRAFEQGWGFILTKTYGLDKDLVTNVSPRIVR------GSTSGPLYGPNQGSFMNIELISEKSCEYWLQCIRELKRDHPTKIVIASIMCVYNKADWIELATKSEEAGADILELNLSCPHGMGEKGMGLACGQSPEIVKEICRWVRACVKIPFFPKMTPNITDVREIARAARDGGASGVTATNTVSSL 755          

BLAST of CK933373 vs. ExPASy Swiss-Prot
Match: DPYD_MOUSE (Dihydropyrimidine dehydrogenase [NADP+] OS=Mus musculus GN=Dpyd PE=2 SV=1)

HSP 1 Score: 183.341 bits (464), Expect = 1.573e-45
Identity = 95/213 (44.60%), Postives = 128/213 (60.09%), Query Frame = 3

Query:  261 DLSITVNGLQMPNPFVIGSGPPGTNYTVMKRAFDEGWGAVVAKTVSLDAAKVINVTPRYARLRAGANGSAKGQIIG-----WENIELISDRPLETMLKEFKQLKALYPDRILIASIMEEYNKAAWEELIDRVEETGIDAIEVNFSCPHGMPERKMGAAVGQDCRLLEEVCGWINAKATVPVWAKMTPNITDITEPARVALRSGSEGASXXNTI 884
            D+S+ + GL+ PNPF + S  P T+  +++RAF+ GWG  + KT SLD   V NV+PR  R      G+  G + G     + NIELIS++          +LKA +PD ILIASIM  YNK+ W EL    E +G DA+E+N SCPHGM ER MG A GQD  L+  +C W+     VP +AK+TPN+TDI   AR A   G++G +  NT+
Sbjct:  532 DISVEMAGLRFPNPFGLASATPATSTPMIRRAFEAGWGFALTKTFSLDKDIVTNVSPRIIR------GTTSGPLYGPGQSSFLNIELISEKTAAYWCHSVTELKADFPDNILIASIMCSYNKSDWMELSKMAEASGADALELNLSCPHGMGERGMGLACGQDPELVRNICRWVRQAVRVPFFAKLTPNVTDIVSIARAAKEGGADGVTATNTV 738          

BLAST of CK933373 vs. ExPASy Swiss-Prot
Match: DPYD_RAT (Dihydropyrimidine dehydrogenase [NADP+] OS=Rattus norvegicus GN=Dpyd PE=2 SV=1)

HSP 1 Score: 182.57 bits (462), Expect = 2.683e-45
Identity = 95/213 (44.60%), Postives = 127/213 (59.62%), Query Frame = 3

Query:  261 DLSITVNGLQMPNPFVIGSGPPGTNYTVMKRAFDEGWGAVVAKTVSLDAAKVINVTPRYARLRAGANGSAKGQIIG-----WENIELISDRPLETMLKEFKQLKALYPDRILIASIMEEYNKAAWEELIDRVEETGIDAIEVNFSCPHGMPERKMGAAVGQDCRLLEEVCGWINAKATVPVWAKMTPNITDITEPARVALRSGSEGASXXNTI 884
            D+S+ + GL+ PNPF + S  P T+  +++RAF+ GWG  + KT SLD   V NV+PR  R      G+  G + G     + NIELIS++          +LKA +PD ILIASIM  YNK  W EL    E +G DA+E+N SCPHGM ER MG A GQD  L+  +C W+     VP +AK+TPN+TDI   AR A   G++G +  NT+
Sbjct:  532 DISVEMAGLRFPNPFGLASATPATSTPMIRRAFEAGWGFALTKTFSLDKDIVTNVSPRIIR------GTTSGPLYGPGQSSFLNIELISEKTAAYWCHSVTELKADFPDNILIASIMCSYNKNDWMELSKMAEASGADALELNLSCPHGMGERGMGLACGQDPELVRNICRWVRQSVRVPFFAKLTPNVTDIVSIARAAKEGGADGVTATNTV 738          

BLAST of CK933373 vs. ExPASy Swiss-Prot
Match: DPYD_DANRE (Dihydropyrimidine dehydrogenase [NADP+] OS=Danio rerio GN=dpyd PE=2 SV=1)

HSP 1 Score: 181.415 bits (459), Expect = 5.977e-45
Identity = 90/213 (42.25%), Postives = 130/213 (61.03%), Query Frame = 3

Query:  261 DLSITVNGLQMPNPFVIGSGPPGTNYTVMKRAFDEGWGAVVAKTVSLDAAKVINVTPRYARLRAGANGSAKGQIIG-----WENIELISDRPLETMLKEFKQLKALYPDRILIASIMEEYNKAAWEELIDRVEETGIDAIEVNFSCPHGMPERKMGAAVGQDCRLLEEVCGWINAKATVPVWAKMTPNITDITEPARVALRSGSEGASXXNTI 884
            D+S+ + G++ PNPF + S PP T+  +++RAF++GWG  + KT  LD   V NV+PR  R      G+  G I G     + NIELIS++      K   +LKA +P  I+IASIM  YN+A W EL    +E+  DA+E+N SCPHGM ER MG A GQD  L+  +C W+    ++P +AK+TPN+T+I + A  A   G++G +  NT+
Sbjct:  532 DISVEMCGIKFPNPFGLASAPPTTSAAMIRRAFEQGWGFALTKTFGLDKDLVTNVSPRIVR------GTTSGHIFGPGQGSFLNIELISEKTAAYWCKSVAELKADFPKNIIIASIMCSYNQADWTELAKMAQESQADALELNLSCPHGMGERGMGLACGQDPELVRNICRWVRKATSIPFFAKLTPNVTNIVDIATAAYEGGADGVTATNTV 738          

BLAST of CK933373 vs. ExPASy Swiss-Prot
Match: DPYD_PONAB (Dihydropyrimidine dehydrogenase [NADP+] OS=Pongo abelii GN=DPYD PE=2 SV=1)

HSP 1 Score: 180.259 bits (456), Expect = 1.332e-44
Identity = 97/232 (41.81%), Postives = 135/232 (58.19%), Query Frame = 3

Query:  240 ASASAEP------------DLSITVNGLQMPNPFVIGSGPPGTNYTVMKRAFDEGWGAVVAKTVSLDAAKVINVTPRYARLRAGANGSAKGQIIG-----WENIELISDRPLETMLKEFKQLKALYPDRILIASIMEEYNKAAWEELIDRVEETGIDAIEVNFSCPHGMPERKMGAAVGQDCRLLEEVCGWINAKATVPVWAKMTPNITDITEPARVALRSGSEGASXXNTI 884
            AS SA+P            D+S+ + GL+  NPF + S  P T+ ++++RAF+ GWG  + KT SLD   V NV+PR  R      G+  G + G     + NIELIS++      +   +LKA +PD I+IASIM  YNK  W EL  + E++G DA+E+N SCPHGM ER MG A GQD  L+  +C W+     +P +AK+TPN+TDI   AR A   G+ G +  NT+
Sbjct:  513 ASVSAKPELPLFYTAIDLVDISVEMAGLKFINPFGLASATPATSTSMIRRAFEAGWGFALTKTFSLDKDIVTNVSPRIVR------GTTSGPMYGPGQSSFLNIELISEKTAAYWCQSVTELKADFPDNIVIASIMCSYNKNDWTELAKKSEDSGADALELNLSCPHGMGERGMGLACGQDPELVRNICRWVRQAVQIPFFAKLTPNVTDIVSIARAAKEGGANGVTATNTV 738          

BLAST of CK933373 vs. ExPASy Swiss-Prot
Match: DPYD_HUMAN (Dihydropyrimidine dehydrogenase [NADP+] OS=Homo sapiens GN=DPYD PE=1 SV=2)

HSP 1 Score: 179.874 bits (455), Expect = 1.739e-44
Identity = 97/232 (41.81%), Postives = 135/232 (58.19%), Query Frame = 3

Query:  240 ASASAEP------------DLSITVNGLQMPNPFVIGSGPPGTNYTVMKRAFDEGWGAVVAKTVSLDAAKVINVTPRYARLRAGANGSAKGQIIG-----WENIELISDRPLETMLKEFKQLKALYPDRILIASIMEEYNKAAWEELIDRVEETGIDAIEVNFSCPHGMPERKMGAAVGQDCRLLEEVCGWINAKATVPVWAKMTPNITDITEPARVALRSGSEGASXXNTI 884
            AS SA+P            D+S+ + GL+  NPF + S  P T+ ++++RAF+ GWG  + KT SLD   V NV+PR  R      G+  G + G     + NIELIS++      +   +LKA +PD I+IASIM  YNK  W EL  + E++G DA+E+N SCPHGM ER MG A GQD  L+  +C W+     +P +AK+TPN+TDI   AR A   G+ G +  NT+
Sbjct:  513 ASVSAKPELPLFYTPIDLVDISVEMAGLKFINPFGLASATPATSTSMIRRAFEAGWGFALTKTFSLDKDIVTNVSPRIIR------GTTSGPMYGPGQSSFLNIELISEKTAAYWCQSVTELKADFPDNIVIASIMCSYNKNDWTELAKKSEDSGADALELNLSCPHGMGERGMGLACGQDPELVRNICRWVRQAVQIPFFAKLTPNVTDIVSIARAAKEGGANGVTATNTV 738          

BLAST of CK933373 vs. ExPASy Swiss-Prot
Match: DPYD_CAEBR (Probable dihydropyrimidine dehydrogenase [NADP+] OS=Caenorhabditis briggsae GN=dpyd-1 PE=3 SV=2)

HSP 1 Score: 179.489 bits (454), Expect = 2.271e-44
Identity = 92/218 (42.20%), Postives = 133/218 (61.01%), Query Frame = 3

Query:  255 EPDLSITVNGLQMPNPFVIGSGPPGTNYTVMKRAFDEGWGAVVAKTVSLDAAKVINVTPRYARLRAGANGSAKGQIIG-----WENIELISDRPLETMLKEFKQLKALYPDRILIASIMEEYNKAAWEELIDRVEETGIDAIEVNFSCPHGMPERKMGAAVGQDCRLLEEVCGWINAKATVPVWAKMTPNITDITEPARVALRSGSEGASXXNTIMSV 893
            E D+S+ + G++  NPF + S PP T+  + +RAF++GWG ++ KT  LD   V NV+PR  R      GS  G + G     + NIELIS++  E  L+  ++LK  +P +I++ASIM  YNK  W EL  + E  G D +E+N SCPHGM E+ MG A GQ   +++E+C W+ A   +P + KMTPNITD+ E AR A   G+ G +  NT+ S+
Sbjct:  554 EVDISVDMCGVKFENPFGLASAPPTTSGPMCRRAFEQGWGFILTKTYGLDKDLVTNVSPRIVR------GSTSGPLYGPNQGSFMNIELISEKSCEYWLQCIRELKRDHPTKIVVASIMCVYNKEDWIELATKSEAAGADILELNLSCPHGMGEKGMGLACGQSPEIVKEICRWVRACVKIPFFPKMTPNITDVREIARAARDGGASGVTATNTVSSL 765          

BLAST of CK933373 vs. ExPASy Swiss-Prot
Match: DPYD_PIG (Dihydropyrimidine dehydrogenase [NADP+] OS=Sus scrofa GN=DPYD PE=1 SV=1)

HSP 1 Score: 178.718 bits (452), Expect = 3.874e-44
Identity = 97/232 (41.81%), Postives = 135/232 (58.19%), Query Frame = 3

Query:  240 ASASAEP------------DLSITVNGLQMPNPFVIGSGPPGTNYTVMKRAFDEGWGAVVAKTVSLDAAKVINVTPRYARLRAGANGSAKGQIIG-----WENIELISDRPLETMLKEFKQLKALYPDRILIASIMEEYNKAAWEELIDRVEETGIDAIEVNFSCPHGMPERKMGAAVGQDCRLLEEVCGWINAKATVPVWAKMTPNITDITEPARVALRSGSEGASXXNTI 884
            AS SA+P            D+S+ + GL+  NPF + S  P T+ ++++RAF+ GWG  + KT SLD   V NV+PR  R      G+  G + G     + NIELIS++      +   +LKA +PD I+IASIM  YNK  W EL  + E +G DA+E+N SCPHGM ER MG A GQD  L+  +C W+     +P +AK+TPN+TDI   AR A   G++G +  NT+
Sbjct:  513 ASVSAKPELPLFYTPVDLVDISVEMAGLKFINPFGLASAAPTTSSSMIRRAFEAGWGFALTKTFSLDKDIVTNVSPRIVR------GTTSGPMYGPGQSSFLNIELISEKTAAYWCQSVTELKADFPDNIVIASIMCSYNKNDWMELSRKAEASGADALELNLSCPHGMGERGMGLACGQDPELVRNICRWVRQAVQIPFFAKLTPNVTDIVSIARAAKEGGADGVTATNTV 738          

BLAST of CK933373 vs. ExPASy Swiss-Prot
Match: DPYD_DICDI (Dihydropyrimidine dehydrogenase [NADP+] OS=Dictyostelium discoideum GN=pyd1 PE=2 SV=1)

HSP 1 Score: 178.333 bits (451), Expect = 5.060e-44
Identity = 89/208 (42.79%), Postives = 128/208 (61.54%), Query Frame = 3

Query:  261 DLSITVNGLQMPNPFVIGSGPPGTNYTVMKRAFDEGWGAVVAKTVSLDAAKVINVTPRYARLRAGANGSAKGQIIGWENIELISDRPLETMLKEFKQLKALYPDRILIASIMEEYNKAAWEELIDRVEETGIDAIEVNFSCPHGMPERKMGAAVGQDCRLLEEVCGWINAKATVPVWAKMTPNITDITEPARVALRSGSEGASXXNTI 884
            D+S+ + G++ PNPF + S  P T+  +++R+F++GWG  V KT SLD   V NV+PR  R     +    GQ   + NIELIS++      K   +LK  +PDRI+IASIM  +NK  W +L    E +G D IE+N SCPHGM E+ MG A GQD  L+  +C W+ A   +P +AK+TPN+T+I E A+ A   G++G +  NT+
Sbjct:  530 DISVEMCGMKFPNPFGLASATPATSAAMIRRSFEQGWGFAVTKTFSLDKDLVTNVSPRIVRGTTSGHHFGPGQG-AFLNIELISEKTCHYWCKAIGELKRDFPDRIVIASIMCGFNKEDWTQLAKMAEASGADGIELNLSCPHGMGEKGMGLACGQDTELVFHICQWVRAATRLPFFAKLTPNVTEIKEIAKAAHDGGADGVTAINTV 736          

BLAST of CK933373 vs. ExPASy Swiss-Prot
Match: DPYD_BOVIN (Dihydropyrimidine dehydrogenase [NADP+] OS=Bos taurus GN=DPYD PE=1 SV=1)

HSP 1 Score: 172.555 bits (436), Expect = 2.777e-42
Identity = 94/232 (40.52%), Postives = 132/232 (56.90%), Query Frame = 3

Query:  240 ASASAEP------------DLSITVNGLQMPNPFVIGSGPPGTNYTVMKRAFDEGWGAVVAKTVSLDAAKVINVTPRYARLRAGANGSAKGQIIG-----WENIELISDRPLETMLKEFKQLKALYPDRILIASIMEEYNKAAWEELIDRVEETGIDAIEVNFSCPHGMPERKMGAAVGQDCRLLEEVCGWINAKATVPVWAKMTPNITDITEPARVALRSGSEGASXXNTI 884
            AS SA+P            D+S+ +  L+  NPF + S  P T+ ++++RAF+ GW   + KT SLD   V NV+PR  R      G+  G + G     + NIELIS++      +   +LKA +PD I+IASIM  YN+  W EL  + E +G DA+E+N SCPHGM ER MG A GQD  L+  +C W+     +P +AK+TPN+TDI   AR A   G+ G +  NT+
Sbjct:  513 ASVSAKPELPLFYTPIDLVDISVEMAALKFTNPFGLASATPTTSSSMIRRAFEAGWAFALTKTFSLDKDIVTNVSPRIIR------GTTSGPMYGPGQSSFLNIELISEKTAAYWCQSVTELKADFPDNIVIASIMCSYNRNDWMELSRKAEASGADALELNLSCPHGMGERGMGLACGQDPELVRNICRWVRQAVRIPFFAKLTPNVTDIVSIARAAKEGGANGVTATNTV 738