EY729436

BLAST of EY729436 vs. ExPASy Swiss-Prot
Match: FOLC_BACSU (Folylpolyglutamate synthase OS=Bacillus subtilis GN=folC PE=3 SV=2)

HSP 1 Score: 113.62 bits (283), Expect = 4.396e-28
Identity = 60/133 (45.11%), Postives = 86/133 (64.66%), Query Frame = 2

Query:  116 LGRMNRLMDRLGNPHSKFKTVHIAGTKGKGSTAAFLSSILRAEGYSVGCYTSPHIKTIRERMNVGRLNRPVSAKALNCLFHKIKGVLDEAIRLENGCITHFEVLTAMAFALFAQNH-VDIAVIEAGLGGARDA 511
            LGRM +LM RLG+P  K +  H+AGT GKGST AF+ S+L+  GY+VG +TSP+I T  ER++V  +  P+S +    L +++K  ++   + E G  T FE++TA AF  FA+ H VD  + E GLGG  D+
Sbjct:   24 LGRMKQLMARLGHPEKKIRAFHVAGTNGKGSTVAFIRSMLQEAGYTVGTFTSPYIITFNERISVNGI--PISDEEWTALVNQMKPHVEALDQTEYGQPTEFEIMTACAFLYFAEFHKVDFVIFETGLGGRFDS 154          

HSP 2 Score: 32.7278 bits (73), Expect = 4.396e-28
Identity = 16/34 (47.06%), Postives = 22/34 (64.71%), Query Frame = 1

Query:  544 SVITTIGEEHTAALSGSLETIAMAXSGIIKYGRP 645
            +VIT+IG +H   L  ++E IA   +GIIK G P
Sbjct:  163 TVITSIGHDHMNILGNTIEEIAGEKAGIIKEGIP 196          

BLAST of EY729436 vs. ExPASy Swiss-Prot
Match: FOLC_BOVIN (Folylpolyglutamate synthase, mitochondrial OS=Bos taurus GN=FPGS PE=2 SV=1)

HSP 1 Score: 89.3521 bits (220), Expect = 3.143e-17
Identity = 47/114 (41.23%), Postives = 72/114 (63.16%), Query Frame = 2

Query:  176 VHIAGTKGKGSTAAFLSSILRAEGYSVGCYTSPHIKTIRERMNVGRLNRPVSAKALNCLFHKIKGVLDEAIRLENGCIT---HFEVLTAMAFALFAQNHVDIAVIEAGLGGARD 508
            +HI GTKGKGST AF   ILR+ G   G ++SPH+  +RER+ +    +P+S++     F ++   L+E  + ++ C++   +F  LT MAF +F Q  VD+AV+E G+GGA D
Sbjct:   96 IHITGTKGKGSTCAFTERILRSYGLKTGFFSSPHLVQVRERIRIN--GQPISSELFTKHFWRLYHRLEET-KDDSSCVSMPGYFRFLTLMAFHVFLQEKVDLAVLEVGIGGAYD 206          

BLAST of EY729436 vs. ExPASy Swiss-Prot
Match: FOLC_HUMAN (Folylpolyglutamate synthase, mitochondrial OS=Homo sapiens GN=FPGS PE=1 SV=3)

HSP 1 Score: 88.9669 bits (219), Expect = 4.104e-17
Identity = 46/118 (38.98%), Postives = 70/118 (59.32%), Query Frame = 2

Query:  164 KFKTVHIAGTKGKGSTAAFLSSILRAEGYSVGCYTSPHIKTIRERMNVGRLNRPVSAKALNCLFHKIKGVLDEAIRLENGCIT---HFEVLTAMAFALFAQNHVDIAVIEAGLGGARD 508
            +   +H+ GTKGKGST AF   ILR+ G   G ++SPH+  +RER+ +    +P+S +     F ++   L+E    +  C++   +F  LT MAF +F Q  VD+AV+E G+GGA D
Sbjct:   95 RLNIIHVTGTKGKGSTCAFTECILRSYGLKTGFFSSPHLVQVRERIRIN--GQPISPELFTKYFWRLYHRLEET--KDGSCVSMPPYFRFLTLMAFHVFLQEKVDLAVVEVGIGGAYD 208          

BLAST of EY729436 vs. ExPASy Swiss-Prot
Match: FOLD_YEAST (Folylpolyglutamate synthase OS=Saccharomyces cerevisiae GN=FOL3 PE=1 SV=1)

HSP 1 Score: 88.1965 bits (217), Expect = 7.001e-17
Identity = 46/132 (34.85%), Postives = 74/132 (56.06%), Query Frame = 2

Query:  116 LGRMNRLMDRLGNPHSKFKTVHIAGTKGKGSTAAFLSSILRAEGYSVGCYTSPHIKTIRERMNVGRLNRPVSAKALNCLFHKIKGVLDEAIRLENGCITHFEVLTAMAFALFAQNHVDIAVIEAGLGGARDA 511
            L R+ +L++ LGNP +  + +HIAGT GKGS   +LSS+L+ + Y +G +T+PH+  + + + +   N+P+  +     +  I+  L+   +  +   T FE+LT  AF  F        VIE GLGG  DA
Sbjct:    7 LSRITKLLEHLGNPQNSLRVLHIAGTNGKGSVCTYLSSVLQQKSYQIGKFTTPHLVHVTDSITIN--NKPIPLER----YQNIRLQLEALNKSHSLKCTEFELLTCTAFKYFYDVQCQWCVIEVGLGGRLDA 132          

BLAST of EY729436 vs. ExPASy Swiss-Prot
Match: FOLC_LACCA (Folylpolyglutamate synthase OS=Lactobacillus casei GN=fgs PE=1 SV=1)

HSP 1 Score: 85.8853 bits (211), Expect = 3.475e-16
Identity = 48/134 (35.82%), Postives = 75/134 (55.97%), Query Frame = 2

Query:  113 DLGRMNRLMDRLGNPHSKFKTVHIAGTKGKGSTAAFLSSILRAEGYSVGCYTSPHIKTIRERMNVGRLNRPVSAKALNCLFHKIKGVLDEAIRLE-NGCITHFEVLTAMAFALFAQNHVDIAVIEAGLGGARDA 511
            D  R+  L+  LGNP  + + +H+ GT GKGS A  ++ +L A G +VG YTSP I    ER+ +   + P+   AL      ++  L+   + + +  +T FE +TA+ +  F Q  VD+AVIE G+GG  D+
Sbjct:   21 DHRRILTLLHALGNPQQQGRYIHVTGTNGKGSAANAIAHVLEASGLTVGLYTSPFIMRFNERIMID--HEPIPDAALVNAVAFVRAALERLQQQQADFNVTEFEFITALGYWYFRQRQVDVAVIEVGIGGDTDS 152          

BLAST of EY729436 vs. ExPASy Swiss-Prot
Match: FOLC_CRIGR (Folylpolyglutamate synthase, mitochondrial OS=Cricetulus griseus GN=FPGS PE=2 SV=1)

HSP 1 Score: 85.5001 bits (210), Expect = 4.538e-16
Identity = 46/120 (38.33%), Postives = 70/120 (58.33%), Query Frame = 2

Query:  161 SKFKTVHIAGTKGKGSTAAFLSSILRAEGYSVGCYTSPHIKTIRERMNVGRLNRPVS----AKALNCLFHKIKGVLDEAIRLENGCITHFEVLTAMAFALFAQNHVDIAVIEAGLGGARD 508
            ++   +H+ GTKGKGST AF   ILR+ G   G ++SPH+  +RER+ +    +P+S     K    L+H+++   D++         +F  LT MAF +F Q  VD+AV+E G+GGA D
Sbjct:   94 NQLNIIHVTGTKGKGSTCAFTERILRSYGLKTGFFSSPHLVQVRERIRIN--GKPISPELFTKHFWRLYHQLEEFKDDS---HVAMPAYFRFLTLMAFHVFLQEKVDLAVVEVGIGGAYD 208          

BLAST of EY729436 vs. ExPASy Swiss-Prot
Match: FOLC_BUCAP (Bifunctional protein folC OS=Buchnera aphidicola subsp. Schizaphis graminum GN=folC PE=3 SV=1)

HSP 1 Score: 74.3294 bits (181), Expect = 5.675e-16
Identity = 49/139 (35.25%), Postives = 71/139 (51.08%), Query Frame = 2

Query:   95 DSDDGFDLGRMNRLMDRLGNPHSKFKTVHIAGTKGKGSTAAFLSSILRAEGYSVGCYTSPHIKTIRERMNVGRLNRPVSAKALNCLFHKIKGVLDEAIRLENGCITHFEVLTAMAFALFAQNHVDIAVIEAGLGGARDA 511
            D  D  +L  +  +  +LG  + K     + GT GKG+T A L  +L   GY VG YTSPH+    ER+ V  L        L+   H    ++ +A +  N  +T+FE +T  A  LF+Q  +DI ++E GLGG  DA
Sbjct:   19 DKKDRKNLFELKLIAKKLGLLNLKSFFFTVGGTNGKGTTCAMLEKLLLDSGYQVGLYTSPHLINYSERIKVNGL-------YLSEKDHIFSFLIIDAEK-GNVSLTYFEFITLSALFLFSQYSLDIIILEVGLGGRLDA 149          

HSP 2 Score: 31.187 bits (69), Expect = 5.675e-16
Identity = 19/44 (43.18%), Postives = 24/44 (54.55%), Query Frame = 1

Query:  511 TNIISSSGLAASVITTIGEEHTAALSGSLETIAMAXSGIIKYGR 642
            TNII S     SVIT IG +HT+ L     +I    SGI + G+
Sbjct:  150 TNIIDSD---LSVITNIGIDHTSCLGTDRISIGREKSGIFRKGK 190          

BLAST of EY729436 vs. ExPASy Swiss-Prot
Match: FOLC_MOUSE (Folylpolyglutamate synthase, mitochondrial OS=Mus musculus GN=Fpgs PE=1 SV=2)

HSP 1 Score: 84.3445 bits (207), Expect = 1.011e-15
Identity = 45/120 (37.50%), Postives = 70/120 (58.33%), Query Frame = 2

Query:  161 SKFKTVHIAGTKGKGSTAAFLSSILRAEGYSVGCYTSPHIKTIRERMNVGRLNRPVS----AKALNCLFHKIKGVLDEAIRLENGCITHFEVLTAMAFALFAQNHVDIAVIEAGLGGARD 508
            ++   +H+ GTKGKGST AF   ILR  G   G + SPH+  +R+R+ +    +P+S     K   CL+++++   D++        ++F  LT MAF +F Q  VD+AV+E G+GGA D
Sbjct:   94 NRLNIIHVTGTKGKGSTCAFTERILRNYGLKTGFFRSPHMVQVRDRIRIN--GKPISPELFTKHFWCLYNQLEEFKDDS---HVSMPSYFRFLTLMAFHVFLQEKVDLAVVEVGIGGAFD 208          

BLAST of EY729436 vs. ExPASy Swiss-Prot
Match: FOLE_SCHPO (Probable folylpolyglutamate synthase OS=Schizosaccharomyces pombe GN=SPBC1709.17 PE=2 SV=1)

HSP 1 Score: 82.4185 bits (202), Expect = 3.842e-15
Identity = 45/125 (36.00%), Postives = 72/125 (57.60%), Query Frame = 2

Query:  161 SKFKTVHIAGTKGKGSTAAFLSSIL--------RAEGYSVGCYTSPHIKTIRERMNVGRLNRPVSAKALNCLFHKIKGVLDEAIRLENGCITHFEVLTAMAFALFAQNHVDIAVIEAGLGGARDA 511
            ++   +H+AGTKGKGST AF SSIL        R+    +G YTSPH++++ ER+ +    +P+S +     F  +   L+ A+  ++    +F  LT MA+ +F   +VD A+IE G+GG  D+
Sbjct:   77 NRLNVIHVAGTKGKGSTCAFTSSILQQIQKSGERSIPKCIGMYTSPHLRSVCERIQLN--GKPISQELFTKYFFDVWERLENAVGSDSEKPMYFRFLTLMAWHVFISENVDAAIIEVGIGGEYDS 199          

BLAST of EY729436 vs. ExPASy Swiss-Prot
Match: FOLE_CANAL (Folylpolyglutamate synthase OS=Candida albicans GN=MET7 PE=3 SV=1)

HSP 1 Score: 79.7221 bits (195), Expect = 2.490e-14
Identity = 56/176 (31.82%), Postives = 87/176 (49.43%), Query Frame = 2

Query:   32 MNYLDSLK-NFEKSGVPKGAGTDSD-DGFDLGRMNRLMDRLG---NPHSKFKTVHIAGTKGKGSTAAFLSSILRAEGYS-VGCYTSPHIKTIRERMNVGRLNRPVSAKALNCLFHKIKGVLDEAIRLENGCIT----------HFEVLTAMAFALFAQNHVDIAVIEAGLGGARDA 511
            +N L+SL+ NF      K  G   + +   +  ++    RLG      +K   +HI GTKGKGST AF  SIL+    S +G YTSPH+K++RER+ +    +P++ +     F ++             C T          +F+ LT ++F +F Q  VD A+ E G+GG  D+
Sbjct:   22 INALNSLQSNFASIEATKKLGPSVNRNELSINEVHEFTKRLGYTPTDFNKLNIIHITGTKGKGSTCAFTESILKQYTISKIGLYTSPHLKSVRERIRIN--GQPINQEKFAKYFFEVWDKFTTTKSDPQECPTLQPCDQVKPMYFKYLTILSFHVFLQEGVDTAIYEVGVGGTYDS 195