EY753373

BLAST of EY753373 vs. ExPASy Swiss-Prot
Match: DPYD_CAEEL (Dihydropyrimidine dehydrogenase [NADP+] OS=Caenorhabditis elegans GN=dpyd-1 PE=2 SV=2)

HSP 1 Score: 147.902 bits (372), Expect = 7.243e-35
Identity = 77/177 (43.50%), Postives = 110/177 (62.15%), Query Frame = 1

Query:  232 EPDLSITVNGLQMPNPFVIGSGPPGTNYTVMKRAFDEGWGAVVAKTVSLDAAKVINVTPRYARLRAGANGSAKGQIIG-----WENIELISDRPLETMLKEFKQLKALYPDRILIASIMEEYNKAAWEELIDRVEETGIDAIEVNFSCPHGMPERKMGAAVGQXCXLLEEVCWWINA 747
            E D+S+ + G++  NPF + S PP T+  + +RAF++GWG ++ KT  LD   V NV+PR  R      GS  G + G     + NIELIS++  E  L+  ++LK  +P +I+IASIM  YNKA W EL  + EE G D +E+N SCPHGM E+ MG A GQ   +++E+C W+ A
Sbjct:  544 EVDISVDMCGVKFENPFGLASAPPTTSGPMCRRAFEQGWGFILTKTYGLDKDLVTNVSPRIVR------GSTSGPLYGPNQGSFMNIELISEKSCEYWLQCIRELKRDHPTKIVIASIMCVYNKADWIELATKSEEAGADILELNLSCPHGMGEKGMGLACGQSPEIVKEICRWVRA 714          

BLAST of EY753373 vs. ExPASy Swiss-Prot
Match: DPYD_DANRE (Dihydropyrimidine dehydrogenase [NADP+] OS=Danio rerio GN=dpyd PE=2 SV=1)

HSP 1 Score: 145.591 bits (366), Expect = 3.595e-34
Identity = 75/173 (43.35%), Postives = 104/173 (60.12%), Query Frame = 1

Query:  238 DLSITVNGLQMPNPFVIGSGPPGTNYTVMKRAFDEGWGAVVAKTVSLDAAKVINVTPRYARLRAGANGSAKGQIIG-----WENIELISDRPLETMLKEFKQLKALYPDRILIASIMEEYNKAAWEELIDRVEETGIDAIEVNFSCPHGMPERKMGAAVGQXCXLLEEVCWWI 741
            D+S+ + G++ PNPF + S PP T+  +++RAF++GWG  + KT  LD   V NV+PR  R      G+  G I G     + NIELIS++      K   +LKA +P  I+IASIM  YN+A W EL    +E+  DA+E+N SCPHGM ER MG A GQ   L+  +C W+
Sbjct:  532 DISVEMCGIKFPNPFGLASAPPTTSAAMIRRAFEQGWGFALTKTFGLDKDLVTNVSPRIVR------GTTSGHIFGPGQGSFLNIELISEKTAAYWCKSVAELKADFPKNIIIASIMCSYNQADWTELAKMAQESQADALELNLSCPHGMGERGMGLACGQDPELVRNICRWV 698          

BLAST of EY753373 vs. ExPASy Swiss-Prot
Match: DPYD_MOUSE (Dihydropyrimidine dehydrogenase [NADP+] OS=Mus musculus GN=Dpyd PE=2 SV=1)

HSP 1 Score: 144.821 bits (364), Expect = 6.132e-34
Identity = 77/173 (44.51%), Postives = 103/173 (59.54%), Query Frame = 1

Query:  238 DLSITVNGLQMPNPFVIGSGPPGTNYTVMKRAFDEGWGAVVAKTVSLDAAKVINVTPRYARLRAGANGSAKGQIIG-----WENIELISDRPLETMLKEFKQLKALYPDRILIASIMEEYNKAAWEELIDRVEETGIDAIEVNFSCPHGMPERKMGAAVGQXCXLLEEVCWWI 741
            D+S+ + GL+ PNPF + S  P T+  +++RAF+ GWG  + KT SLD   V NV+PR  R      G+  G + G     + NIELIS++          +LKA +PD ILIASIM  YNK+ W EL    E +G DA+E+N SCPHGM ER MG A GQ   L+  +C W+
Sbjct:  532 DISVEMAGLRFPNPFGLASATPATSTPMIRRAFEAGWGFALTKTFSLDKDIVTNVSPRIIR------GTTSGPLYGPGQSSFLNIELISEKTAAYWCHSVTELKADFPDNILIASIMCSYNKSDWMELSKMAEASGADALELNLSCPHGMGERGMGLACGQDPELVRNICRWV 698          

BLAST of EY753373 vs. ExPASy Swiss-Prot
Match: DPYD_RAT (Dihydropyrimidine dehydrogenase [NADP+] OS=Rattus norvegicus GN=Dpyd PE=2 SV=1)

HSP 1 Score: 143.665 bits (361), Expect = 1.366e-33
Identity = 77/173 (44.51%), Postives = 102/173 (58.96%), Query Frame = 1

Query:  238 DLSITVNGLQMPNPFVIGSGPPGTNYTVMKRAFDEGWGAVVAKTVSLDAAKVINVTPRYARLRAGANGSAKGQIIG-----WENIELISDRPLETMLKEFKQLKALYPDRILIASIMEEYNKAAWEELIDRVEETGIDAIEVNFSCPHGMPERKMGAAVGQXCXLLEEVCWWI 741
            D+S+ + GL+ PNPF + S  P T+  +++RAF+ GWG  + KT SLD   V NV+PR  R      G+  G + G     + NIELIS++          +LKA +PD ILIASIM  YNK  W EL    E +G DA+E+N SCPHGM ER MG A GQ   L+  +C W+
Sbjct:  532 DISVEMAGLRFPNPFGLASATPATSTPMIRRAFEAGWGFALTKTFSLDKDIVTNVSPRIIR------GTTSGPLYGPGQSSFLNIELISEKTAAYWCHSVTELKADFPDNILIASIMCSYNKNDWMELSKMAEASGADALELNLSCPHGMGERGMGLACGQDPELVRNICRWV 698          

BLAST of EY753373 vs. ExPASy Swiss-Prot
Match: DPYD_DICDI (Dihydropyrimidine dehydrogenase [NADP+] OS=Dictyostelium discoideum GN=pyd1 PE=2 SV=1)

HSP 1 Score: 143.28 bits (360), Expect = 1.784e-33
Identity = 73/170 (42.94%), Postives = 102/170 (60.00%), Query Frame = 1

Query:  238 DLSITVNGLQMPNPFVIGSGPPGTNYTVMKRAFDEGWGAVVAKTVSLDAAKVINVTPRYARLRAGANGSAKGQIIGWENIELISDRPLETMLKEFKQLKALYPDRILIASIMEEYNKAAWEELIDRVEETGIDAIEVNFSCPHGMPERKMGAAVGQXCXLLEEVCWWINA 747
            D+S+ + G++ PNPF + S  P T+  +++R+F++GWG  V KT SLD   V NV+PR  R     +    GQ   + NIELIS++      K   +LK  +PDRI+IASIM  +NK  W +L    E +G D IE+N SCPHGM E+ MG A GQ   L+  +C W+ A
Sbjct:  530 DISVEMCGMKFPNPFGLASATPATSAAMIRRSFEQGWGFAVTKTFSLDKDLVTNVSPRIVRGTTSGHHFGPGQG-AFLNIELISEKTCHYWCKAIGELKRDFPDRIVIASIMCGFNKEDWTQLAKMAEASGADGIELNLSCPHGMGEKGMGLACGQDTELVFHICQWVRA 698          

BLAST of EY753373 vs. ExPASy Swiss-Prot
Match: DPYD_CAEBR (Probable dihydropyrimidine dehydrogenase [NADP+] OS=Caenorhabditis briggsae GN=dpyd-1 PE=3 SV=2)

HSP 1 Score: 143.28 bits (360), Expect = 1.784e-33
Identity = 74/177 (41.81%), Postives = 108/177 (61.02%), Query Frame = 1

Query:  232 EPDLSITVNGLQMPNPFVIGSGPPGTNYTVMKRAFDEGWGAVVAKTVSLDAAKVINVTPRYARLRAGANGSAKGQIIG-----WENIELISDRPLETMLKEFKQLKALYPDRILIASIMEEYNKAAWEELIDRVEETGIDAIEVNFSCPHGMPERKMGAAVGQXCXLLEEVCWWINA 747
            E D+S+ + G++  NPF + S PP T+  + +RAF++GWG ++ KT  LD   V NV+PR  R      GS  G + G     + NIELIS++  E  L+  ++LK  +P +I++ASIM  YNK  W EL  + E  G D +E+N SCPHGM E+ MG A GQ   +++E+C W+ A
Sbjct:  554 EVDISVDMCGVKFENPFGLASAPPTTSGPMCRRAFEQGWGFILTKTYGLDKDLVTNVSPRIVR------GSTSGPLYGPNQGSFMNIELISEKSCEYWLQCIRELKRDHPTKIVVASIMCVYNKEDWIELATKSEAAGADILELNLSCPHGMGEKGMGLACGQSPEIVKEICRWVRA 724          

BLAST of EY753373 vs. ExPASy Swiss-Prot
Match: DPYD_PONAB (Dihydropyrimidine dehydrogenase [NADP+] OS=Pongo abelii GN=DPYD PE=2 SV=1)

HSP 1 Score: 142.895 bits (359), Expect = 2.330e-33
Identity = 80/192 (41.67%), Postives = 111/192 (57.81%), Query Frame = 1

Query:  217 ASASAEP------------DLSITVNGLQMPNPFVIGSGPPGTNYTVMKRAFDEGWGAVVAKTVSLDAAKVINVTPRYARLRAGANGSAKGQIIG-----WENIELISDRPLETMLKEFKQLKALYPDRILIASIMEEYNKAAWEELIDRVEETGIDAIEVNFSCPHGMPERKMGAAVGQXCXLLEEVCWWI 741
            AS SA+P            D+S+ + GL+  NPF + S  P T+ ++++RAF+ GWG  + KT SLD   V NV+PR  R      G+  G + G     + NIELIS++      +   +LKA +PD I+IASIM  YNK  W EL  + E++G DA+E+N SCPHGM ER MG A GQ   L+  +C W+
Sbjct:  513 ASVSAKPELPLFYTAIDLVDISVEMAGLKFINPFGLASATPATSTSMIRRAFEAGWGFALTKTFSLDKDIVTNVSPRIVR------GTTSGPMYGPGQSSFLNIELISEKTAAYWCQSVTELKADFPDNIVIASIMCSYNKNDWTELAKKSEDSGADALELNLSCPHGMGERGMGLACGQDPELVRNICRWV 698          

BLAST of EY753373 vs. ExPASy Swiss-Prot
Match: DPYD_HUMAN (Dihydropyrimidine dehydrogenase [NADP+] OS=Homo sapiens GN=DPYD PE=1 SV=2)

HSP 1 Score: 142.51 bits (358), Expect = 3.043e-33
Identity = 80/192 (41.67%), Postives = 111/192 (57.81%), Query Frame = 1

Query:  217 ASASAEP------------DLSITVNGLQMPNPFVIGSGPPGTNYTVMKRAFDEGWGAVVAKTVSLDAAKVINVTPRYARLRAGANGSAKGQIIG-----WENIELISDRPLETMLKEFKQLKALYPDRILIASIMEEYNKAAWEELIDRVEETGIDAIEVNFSCPHGMPERKMGAAVGQXCXLLEEVCWWI 741
            AS SA+P            D+S+ + GL+  NPF + S  P T+ ++++RAF+ GWG  + KT SLD   V NV+PR  R      G+  G + G     + NIELIS++      +   +LKA +PD I+IASIM  YNK  W EL  + E++G DA+E+N SCPHGM ER MG A GQ   L+  +C W+
Sbjct:  513 ASVSAKPELPLFYTPIDLVDISVEMAGLKFINPFGLASATPATSTSMIRRAFEAGWGFALTKTFSLDKDIVTNVSPRIIR------GTTSGPMYGPGQSSFLNIELISEKTAAYWCQSVTELKADFPDNIVIASIMCSYNKNDWTELAKKSEDSGADALELNLSCPHGMGERGMGLACGQDPELVRNICRWV 698          

BLAST of EY753373 vs. ExPASy Swiss-Prot
Match: DPYD_PIG (Dihydropyrimidine dehydrogenase [NADP+] OS=Sus scrofa GN=DPYD PE=1 SV=1)

HSP 1 Score: 140.584 bits (353), Expect = 1.156e-32
Identity = 80/192 (41.67%), Postives = 110/192 (57.29%), Query Frame = 1

Query:  217 ASASAEP------------DLSITVNGLQMPNPFVIGSGPPGTNYTVMKRAFDEGWGAVVAKTVSLDAAKVINVTPRYARLRAGANGSAKGQIIG-----WENIELISDRPLETMLKEFKQLKALYPDRILIASIMEEYNKAAWEELIDRVEETGIDAIEVNFSCPHGMPERKMGAAVGQXCXLLEEVCWWI 741
            AS SA+P            D+S+ + GL+  NPF + S  P T+ ++++RAF+ GWG  + KT SLD   V NV+PR  R      G+  G + G     + NIELIS++      +   +LKA +PD I+IASIM  YNK  W EL  + E +G DA+E+N SCPHGM ER MG A GQ   L+  +C W+
Sbjct:  513 ASVSAKPELPLFYTPVDLVDISVEMAGLKFINPFGLASAAPTTSSSMIRRAFEAGWGFALTKTFSLDKDIVTNVSPRIVR------GTTSGPMYGPGQSSFLNIELISEKTAAYWCQSVTELKADFPDNIVIASIMCSYNKNDWMELSRKAEASGADALELNLSCPHGMGERGMGLACGQDPELVRNICRWV 698          

BLAST of EY753373 vs. ExPASy Swiss-Prot
Match: DPYD_BOVIN (Dihydropyrimidine dehydrogenase [NADP+] OS=Bos taurus GN=DPYD PE=1 SV=1)

HSP 1 Score: 135.191 bits (339), Expect = 4.858e-31
Identity = 77/192 (40.10%), Postives = 108/192 (56.25%), Query Frame = 1

Query:  217 ASASAEP------------DLSITVNGLQMPNPFVIGSGPPGTNYTVMKRAFDEGWGAVVAKTVSLDAAKVINVTPRYARLRAGANGSAKGQIIG-----WENIELISDRPLETMLKEFKQLKALYPDRILIASIMEEYNKAAWEELIDRVEETGIDAIEVNFSCPHGMPERKMGAAVGQXCXLLEEVCWWI 741
            AS SA+P            D+S+ +  L+  NPF + S  P T+ ++++RAF+ GW   + KT SLD   V NV+PR  R      G+  G + G     + NIELIS++      +   +LKA +PD I+IASIM  YN+  W EL  + E +G DA+E+N SCPHGM ER MG A GQ   L+  +C W+
Sbjct:  513 ASVSAKPELPLFYTPIDLVDISVEMAALKFTNPFGLASATPTTSSSMIRRAFEAGWAFALTKTFSLDKDIVTNVSPRIIR------GTTSGPMYGPGQSSFLNIELISEKTAAYWCQSVTELKADFPDNIVIASIMCSYNRNDWMELSRKAEASGADALELNLSCPHGMGERGMGLACGQDPELVRNICRWV 698