EY710074

BLAST of EY710074 vs. ExPASy Swiss-Prot
Match: IDE_RAT (Insulin-degrading enzyme OS=Rattus norvegicus GN=Ide PE=1 SV=1)

HSP 1 Score: 129.028 bits (323), Expect = 3.816e-29
Identity = 73/174 (41.95%), Postives = 97/174 (55.75%), Query Frame = 3

Query:   27 SKQFEGKTDMVEPWYGTAYSIEKINESIIQDWILSAPEENLHLPAPNVFIPTDLSL----KDAQEAKFPVLLRKSSYSTLWYKPDTMFSTPKAFVKIYFNCPHASSSPESEVLTDIFTRLLLDYLNEYAYYAQVAGLDYGINHTESGFEVTVVGYNHKLRILLETIFQKIAQFQ 536
            SK FEGKTD  E WYGT Y  E I E +IQ W  +       LP  N FIPT+  +    KDA    +P L++ ++ S LW+K D  F  PKA +   F  P A   P    +  ++  LL D LNEYAY A++AGL Y + +T  G  ++V GYN K  ILL+ I +K+A F+
Sbjct:  482 SKSFEGKTDRTEQWYGTQYKQEAIPEDVIQKWQNADLNGKFKLPTKNEFIPTNFEILALEKDA--TPYPALIKDTAMSKLWFKQDDKFFLPKACLNFEFFSPFAYVDPLHCNMAYLYLELLKDSLNEYAYAAELAGLSYDLQNTIYGMYLSVKGYNDKQPILLKKITEKMATFE 653          

BLAST of EY710074 vs. ExPASy Swiss-Prot
Match: IDE_HUMAN (Insulin-degrading enzyme OS=Homo sapiens GN=IDE PE=1 SV=4)

HSP 1 Score: 127.102 bits (318), Expect = 1.450e-28
Identity = 68/172 (39.53%), Postives = 96/172 (55.81%), Query Frame = 3

Query:   27 SKQFEGKTDMVEPWYGTAYSIEKINESIIQDWILSAPEENLHLPAPNVFIPTDLSLK--DAQEAKFPVLLRKSSYSTLWYKPDTMFSTPKAFVKIYFNCPHASSSPESEVLTDIFTRLLLDYLNEYAYYAQVAGLDYGINHTESGFEVTVVGYNHKLRILLETIFQKIAQFQ 536
            SK FEGKTD  E WYGT Y  E I + +I+ W  +       LP  N FIPT+  +   + +   +P L++ ++ S LW+K D  F  PKA +   F  P A   P    +  ++  LL D LNEYAY A++AGL Y + +T  G  ++V GYN K  ILL+ I +K+A F+
Sbjct:  482 SKSFEGKTDRTEEWYGTQYKQEAIPDEVIKKWQNADLNGKFKLPTKNEFIPTNFEILPLEKEATPYPALIKDTAMSKLWFKQDDKFFLPKACLNFEFFSPFAYVDPLHCNMAYLYLELLKDSLNEYAYAAELAGLSYDLQNTIYGMYLSVKGYNDKQPILLKKIIEKMATFE 653          

BLAST of EY710074 vs. ExPASy Swiss-Prot
Match: IDE_MOUSE (Insulin-degrading enzyme OS=Mus musculus GN=Ide PE=2 SV=1)

HSP 1 Score: 125.946 bits (315), Expect = 3.230e-28
Identity = 69/172 (40.12%), Postives = 95/172 (55.23%), Query Frame = 3

Query:   27 SKQFEGKTDMVEPWYGTAYSIEKINESIIQDWILSAPEENLHLPAPNVFIPTDLSLKDAQE--AKFPVLLRKSSYSTLWYKPDTMFSTPKAFVKIYFNCPHASSSPESEVLTDIFTRLLLDYLNEYAYYAQVAGLDYGINHTESGFEVTVVGYNHKLRILLETIFQKIAQFQ 536
            SK FEGKTD  E WYGT Y  E I E +IQ W  +       LP  N FIPT+  +   ++    +P L++ ++ S LW+K D  F  PKA +   F  P A   P    +  ++  LL D LNEYAY A++AGL Y + +T  G  ++V  YN K  ILL+ I +K+A F+
Sbjct:  482 SKSFEGKTDRTEQWYGTQYKQEAIPEDVIQKWQNADLNGKFKLPTKNEFIPTNFEILSLEKDATPYPALIKDTAMSKLWFKQDDKFFLPKACLNFEFFSPFAYVDPLHCNMAYLYLELLKDSLNEYAYAAELAGLSYDLQNTIYGMYLSVKRYNDKQPILLKKITEKMATFE 653          

BLAST of EY710074 vs. ExPASy Swiss-Prot
Match: IDE_BOVIN (Insulin-degrading enzyme OS=Bos taurus GN=IDE PE=2 SV=1)

HSP 1 Score: 125.946 bits (315), Expect = 3.230e-28
Identity = 68/172 (39.53%), Postives = 96/172 (55.81%), Query Frame = 3

Query:   27 SKQFEGKTDMVEPWYGTAYSIEKINESIIQDWILSAPEENLHLPAPNVFIPTDLSLKDAQE--AKFPVLLRKSSYSTLWYKPDTMFSTPKAFVKIYFNCPHASSSPESEVLTDIFTRLLLDYLNEYAYYAQVAGLDYGINHTESGFEVTVVGYNHKLRILLETIFQKIAQFQ 536
            SK FEGKTD  E WYGT Y  E I + +I+ W  +       LP  N FIPT+  +   ++    +P L++ ++ S LW+K D  F  PKA +   F  P A   P    +  ++  LL D LNEYAY A++AGL Y + +T  G  ++V GYN K  ILL+ I +K+A F+
Sbjct:  482 SKSFEGKTDRTEEWYGTQYKQEAIPDEVIKKWQNADLNGKFKLPMKNEFIPTNFEILSLEKEATPYPSLIKDTAMSKLWFKQDDKFFLPKACLNFEFFSPFAYVDPLHCNMAYLYLELLKDSLNEYAYAAELAGLSYDLQNTIYGMYLSVKGYNDKQPILLKKIIEKMATFE 653          

BLAST of EY710074 vs. ExPASy Swiss-Prot
Match: NRDC_HUMAN (Nardilysin OS=Homo sapiens GN=NRD1 PE=1 SV=2)

HSP 1 Score: 122.094 bits (305), Expect = 4.664e-27
Identity = 68/168 (40.48%), Postives = 93/168 (55.36%), Query Frame = 3

Query:   39 EGKTDMVEPWYGTAYSIEKINESIIQDWILSAP-EENLHLPAPNVFIPTDLSLK--DAQEAKFPVLLRKSSYSTLWYKPDTMFSTPKAFVKIYFNCPHASSSPESEVLTDIFTRLLLDYLNEYAYYAQVAGLDYGINHTESGFEVTVVGYNHKLRILLETIFQKIAQF 533
            EGK D+ E W+GT YSIE I  S  + W  +     +LHLPA N +I TD +LK  D  E ++PV +  +    LWYK D  F  PKA+++ +   P    S  + VL DIF  +L   L E AY A VA L+Y +   E G  + V G+NHKL +L + I   +A+F
Sbjct:  616 EGKCDLKEKWFGTQYSIEDIENSWAELWNSNFELNPDLHLPAENKYIATDFTLKAFDCPETEYPVKIVNTPQGCLWYKKDNKFKIPKAYIRFHLISPLIQKSAANVVLFDIFVNILTHNLAEPAYEADVAQLEYKLVAGEHGLIIRVKGFNHKLPLLFQLIIDYLAEF 783          

BLAST of EY710074 vs. ExPASy Swiss-Prot
Match: NRDC_PONAB (Nardilysin OS=Pongo abelii GN=NRD1 PE=2 SV=1)

HSP 1 Score: 121.324 bits (303), Expect = 7.956e-27
Identity = 68/168 (40.48%), Postives = 93/168 (55.36%), Query Frame = 3

Query:   39 EGKTDMVEPWYGTAYSIEKINESIIQDWILSAP-EENLHLPAPNVFIPTDLSLK--DAQEAKFPVLLRKSSYSTLWYKPDTMFSTPKAFVKIYFNCPHASSSPESEVLTDIFTRLLLDYLNEYAYYAQVAGLDYGINHTESGFEVTVVGYNHKLRILLETIFQKIAQF 533
            EGK D+ E W+GT YSIE I  S  + W  +     +LHLPA N +I TD +LK  D  E ++PV +  +    LWYK D  F  PKA+++ +   P    S  + VL DIF  +L   L E AY A VA L+Y +   E G  + V G+NHKL +L + I   +A+F
Sbjct:  618 EGKCDLKEKWFGTQYSIEDIENSWAELWNSNFELNPDLHLPAENKYIATDFTLKAFDCPETEYPVKIVNTPQGCLWYKKDNKFKIPKAYIRFHLISPLIQRSAANVVLFDIFANILTHNLAEPAYEADVAQLEYKLVAGEHGLIIRVKGFNHKLPLLFQLIVDYLAEF 785          

BLAST of EY710074 vs. ExPASy Swiss-Prot
Match: NRDC_MOUSE (Nardilysin OS=Mus musculus GN=Nrd1 PE=1 SV=1)

HSP 1 Score: 118.627 bits (296), Expect = 5.157e-26
Identity = 65/168 (38.69%), Postives = 92/168 (54.76%), Query Frame = 3

Query:   39 EGKTDMVEPWYGTAYSIEKINESIIQDWILSAP-EENLHLPAPNVFIPTDLSLK--DAQEAKFPVLLRKSSYSTLWYKPDTMFSTPKAFVKIYFNCPHASSSPESEVLTDIFTRLLLDYLNEYAYYAQVAGLDYGINHTESGFEVTVVGYNHKLRILLETIFQKIAQF 533
            EG+ D+ E W+GT YSIE I  S  + W  +     +LHLPA N +I TD +LK  D  E ++P  +  ++   LWYK D  F  PKA+++ +   P    S  + VL DIF  +L   L E AY A VA L+Y +   E G  + V G+NHKL +L + I   + +F
Sbjct:  628 EGRCDLKEKWFGTQYSIEDIENSWTELWKSNFDLNPDLHLPAENKYIATDFTLKAFDCPETEYPAKIVNTAQGCLWYKKDNKFKIPKAYIRFHLISPLIQKSAANVVLFDIFVNILTHNLAEPAYEADVAQLEYKLVAGEHGLIIRVKGFNHKLPLLFQLIIDYLTEF 795          

BLAST of EY710074 vs. ExPASy Swiss-Prot
Match: NRDC_RAT (Nardilysin OS=Rattus norvegicus GN=Nrd1 PE=2 SV=1)

HSP 1 Score: 118.242 bits (295), Expect = 6.735e-26
Identity = 65/168 (38.69%), Postives = 91/168 (54.17%), Query Frame = 3

Query:   39 EGKTDMVEPWYGTAYSIEKINESIIQDWILSAP-EENLHLPAPNVFIPTDLSLK--DAQEAKFPVLLRKSSYSTLWYKPDTMFSTPKAFVKIYFNCPHASSSPESEVLTDIFTRLLLDYLNEYAYYAQVAGLDYGINHTESGFEVTVVGYNHKLRILLETIFQKIAQF 533
            EG+ D+ E W+GT YSIE I  S  + W  +     +LHLPA N +I TD +LK  D  E ++P  +  +    LWYK D  F  PKA+++ +   P    S  + VL DIF  +L   L E AY A VA L+Y +   E G  + V G+NHKL +L + I   + +F
Sbjct:  628 EGRCDLKEKWFGTQYSIEDIENSWTELWKSNFDLNSDLHLPAENKYIATDFTLKAFDCPETEYPAKIVNTPQGCLWYKKDNKFKIPKAYIRFHLISPLIQKSAANVVLFDIFVNILTHNLAEPAYEADVAQLEYKLVAGEHGLIIRVKGFNHKLPLLFQLIIDYLTEF 795          

BLAST of EY710074 vs. ExPASy Swiss-Prot
Match: IDE_DROME (Insulin-degrading enzyme OS=Drosophila melanogaster GN=Ide PE=1 SV=4)

HSP 1 Score: 101.679 bits (252), Expect = 6.524e-21
Identity = 56/171 (32.75%), Postives = 85/171 (49.71%), Query Frame = 3

Query:   27 SKQFEGKTDMVEPWYGTAYSIEKINESIIQDWILSAPEENLHLPAPNVFIPTDLSLKD--AQEAKFPVLLRKSSYSTLWYKPDTMFSTPKAFVKIYFNCPHASSSPESEVLTDIFTRLLLDYLNEYAYYAQVAGLDYGINHTESGFEVTVVGYNHKLRILLETIFQKIAQF 533
            S+ FE   D+ EP+Y T Y I ++ +  +Q W      ENL L  PN FIPT+  + D  A   K P ++  +    +W+K D  F+ PKA +    + P A   P +  L  +   LL D LNEY Y A++A L   +     G + T+ G++ K  +LLE +   +  F
Sbjct:  455 SQSFEPDCDLAEPYYKTKYGITRVAKDTVQSWENCELNENLKLALPNSFIPTNFDISDVPADAPKHPTIILDTPILRVWHKQDNQFNKPKACMTFDMSNPIAYLDPLNCNLNHMMVMLLKDQLNEYLYDAELASLKLSVMGKSCGIDFTIRGFSDKQVVLLEKLLDHLFDF 625          

BLAST of EY710074 vs. ExPASy Swiss-Prot
Match: STE23_YEAST (A-factor-processing enzyme OS=Saccharomyces cerevisiae GN=STE23 PE=1 SV=2)

HSP 1 Score: 99.7525 bits (247), Expect = 2.479e-20
Identity = 56/167 (33.53%), Postives = 80/167 (47.90%), Query Frame = 3

Query:   45 KTDMVEPWYGTAYSIEKINESIIQDWILSAPEENLHLPAPNVFIPTDLSLKDAQEAK---FPVLLRKSSYSTLWYKPDTMFSTPKAFVKIYFNCPHASSSPESEVLTDIFTRLLLDYLNEYAYYAQVAGLDYGINHTESGFEVTVVGYNHKLRILLETIFQKIAQFQ 536
            +TD  E WYGTAY +      +I++         L LP PN F+ T+  +      K    PVLL     S LWYK D  F  P+ ++ + F  PH  +S  + +L+ ++T+L  D L +  Y A  A L    N T  G  +T  G+N KL ILL    Q +  F+
Sbjct:  497 ETDSAEKWYGTAYKVVDYPADLIKNMKSPGLNPALTLPRPNEFVSTNFKVDKIDGIKPLDEPVLLLSDDVSKLWYKKDDRFWQPRGYIYLSFKLPHTHASIINSMLSTLYTQLANDALKDVQYDAACADLRISFNKTNQGLAITASGFNEKLIILLTRFLQGVNSFE 663