EY664150

BLAST of EY664150 vs. ExPASy Swiss-Prot
Match: IDE_HUMAN (Insulin-degrading enzyme OS=Homo sapiens GN=IDE PE=1 SV=4)

HSP 1 Score: 127.102 bits (318), Expect = 7.126e-32
Identity = 81/223 (36.32%), Postives = 115/223 (51.57%), Query Frame = 2

Query:   89 GYNHKLRILLETIFQKIAQFKVKPDRFSVIKEMVTKEYHNNKFLQPFQLAMYYCSLILQDQTWPWMEELEVLPHLEAEDLAKFVPMMLSRTFLECYIAGNIESNEAGSMIQYIEDVFFKGSNPICQPLFPSQHLTNRVVKLEKGKNYVYSNQGLNPSDENSCLVHYIQVHRDDFLMNVKLQLLALIAKQPAFHQLRTVEQLGYITALLQRNDFGIHGVQFIIQ 757
            GYN K  ILL+ I +K+A F++   RF +IKE   +  +N +  QP Q AMYY  L++ +  W   E  E L  +    L  F+P +LSR  +E  + GNI    A  ++Q +ED   + ++   +PL PSQ +  R V+L     +VY  Q  N    N  +  Y Q        N+ L+L   I  +P F+ LRT EQLGYI     R   GI G++FIIQ
Sbjct:  633 GYNDKQPILLKKIIEKMATFEIDEKRFEIIKEAYMRSLNNFRAEQPHQHAMYYLRLLMTEVAWTKDELKEALDDVTLPRLKAFIPQLLSRLHIEALLHGNITKQAALGIMQMVEDTLIEHAH--TKPLLPSQLVRYREVQLPDRGWFVY--QQRNEVHNNCGIEIYYQTDMQSTSENMFLELFCQIISEPCFNTLRTKEQLGYIVFSGPRRANGIQGLRFIIQ 851          

HSP 2 Score: 31.9574 bits (71), Expect = 7.126e-32
Identity = 14/28 (50.00%), Postives = 20/28 (71.43%), Query Frame = 3

Query:    3 LNEYAYYAQVAGLDYGINHTESGFEVTV 86
            LNEYAY A++AGL Y + +T  G  ++V
Sbjct:  604 LNEYAYAAELAGLSYDLQNTIYGMYLSV 631          

BLAST of EY664150 vs. ExPASy Swiss-Prot
Match: IDE_BOVIN (Insulin-degrading enzyme OS=Bos taurus GN=IDE PE=2 SV=1)

HSP 1 Score: 127.102 bits (318), Expect = 7.126e-32
Identity = 81/223 (36.32%), Postives = 115/223 (51.57%), Query Frame = 2

Query:   89 GYNHKLRILLETIFQKIAQFKVKPDRFSVIKEMVTKEYHNNKFLQPFQLAMYYCSLILQDQTWPWMEELEVLPHLEAEDLAKFVPMMLSRTFLECYIAGNIESNEAGSMIQYIEDVFFKGSNPICQPLFPSQHLTNRVVKLEKGKNYVYSNQGLNPSDENSCLVHYIQVHRDDFLMNVKLQLLALIAKQPAFHQLRTVEQLGYITALLQRNDFGIHGVQFIIQ 757
            GYN K  ILL+ I +K+A F++   RF +IKE   +  +N +  QP Q AMYY  L++ +  W   E  E L  +    L  F+P +LSR  +E  + GNI    A  ++Q +ED   + ++   +PL PSQ +  R V+L     +VY  Q  N    N  +  Y Q        N+ L+L   I  +P F+ LRT EQLGYI     R   GI G++FIIQ
Sbjct:  633 GYNDKQPILLKKIIEKMATFEIDEKRFEIIKEAYMRSLNNFRAEQPHQHAMYYLRLLMTEVAWTKDELKEALDDVTLPRLKAFIPQLLSRLHIEALLHGNITKQAALGIMQMVEDTLIEHAH--TKPLLPSQLVRYREVQLPDRGWFVY--QQRNEVHNNCGIEIYYQTDMQSTSENMFLELFCQIISEPCFNTLRTKEQLGYIVFSGPRRANGIQGLRFIIQ 851          

HSP 2 Score: 31.9574 bits (71), Expect = 7.126e-32
Identity = 14/28 (50.00%), Postives = 20/28 (71.43%), Query Frame = 3

Query:    3 LNEYAYYAQVAGLDYGINHTESGFEVTV 86
            LNEYAY A++AGL Y + +T  G  ++V
Sbjct:  604 LNEYAYAAELAGLSYDLQNTIYGMYLSV 631          

BLAST of EY664150 vs. ExPASy Swiss-Prot
Match: IDE_RAT (Insulin-degrading enzyme OS=Rattus norvegicus GN=Ide PE=1 SV=1)

HSP 1 Score: 126.331 bits (316), Expect = 1.208e-31
Identity = 81/223 (36.32%), Postives = 115/223 (51.57%), Query Frame = 2

Query:   89 GYNHKLRILLETIFQKIAQFKVKPDRFSVIKEMVTKEYHNNKFLQPFQLAMYYCSLILQDQTWPWMEELEVLPHLEAEDLAKFVPMMLSRTFLECYIAGNIESNEAGSMIQYIEDVFFKGSNPICQPLFPSQHLTNRVVKLEKGKNYVYSNQGLNPSDENSCLVHYIQVHRDDFLMNVKLQLLALIAKQPAFHQLRTVEQLGYITALLQRNDFGIHGVQFIIQ 757
            GYN K  ILL+ I +K+A F++   RF +IKE   +  +N +  QP Q AMYY  L++ +  W   E  E L  +    L  F+P +LSR  +E  + GNI    A  ++Q +ED   + ++   +PL PSQ +  R V+L     +VY  Q  N    N  +  Y Q        N+ L+L   I  +P F+ LRT EQLGYI     R   GI G++FIIQ
Sbjct:  633 GYNDKQPILLKKITEKMATFEIDKKRFEIIKEAYMRSLNNFRAEQPHQHAMYYLRLLMTEVAWTKDELKEALDDVTLPRLKAFIPQLLSRLHIEALLHGNITKQAALGVMQMVEDTLIEHAH--TKPLLPSQLVRYREVQLPDRGWFVY--QRRNEVHNNCGIEIYYQTDMQSTSENMFLELFCQIISEPCFNTLRTKEQLGYIVFSGPRRANGIQGLRFIIQ 851          

HSP 2 Score: 31.9574 bits (71), Expect = 1.208e-31
Identity = 14/28 (50.00%), Postives = 20/28 (71.43%), Query Frame = 3

Query:    3 LNEYAYYAQVAGLDYGINHTESGFEVTV 86
            LNEYAY A++AGL Y + +T  G  ++V
Sbjct:  604 LNEYAYAAELAGLSYDLQNTIYGMYLSV 631          

BLAST of EY664150 vs. ExPASy Swiss-Prot
Match: IDE_MOUSE (Insulin-degrading enzyme OS=Mus musculus GN=Ide PE=2 SV=1)

HSP 1 Score: 124.02 bits (310), Expect = 5.890e-31
Identity = 80/222 (36.04%), Postives = 114/222 (51.35%), Query Frame = 2

Query:   92 YNHKLRILLETIFQKIAQFKVKPDRFSVIKEMVTKEYHNNKFLQPFQLAMYYCSLILQDQTWPWMEELEVLPHLEAEDLAKFVPMMLSRTFLECYIAGNIESNEAGSMIQYIEDVFFKGSNPICQPLFPSQHLTNRVVKLEKGKNYVYSNQGLNPSDENSCLVHYIQVHRDDFLMNVKLQLLALIAKQPAFHQLRTVEQLGYITALLQRNDFGIHGVQFIIQ 757
            YN K  ILL+ I +K+A F++   RF +IKE   +  +N +  QP Q AMYY  L++ +  W   E  E L  +    L  F+P +LSR  +E  + GNI    A  ++Q +ED   + ++   +PL PSQ +  R V+L     +VY  Q  N    N  +  Y Q        N+ L+L   I  +P F+ LRT EQLGYI     R   GI G++FIIQ
Sbjct:  634 YNDKQPILLKKITEKMATFEIDKKRFEIIKEAYMRSLNNFRAEQPHQHAMYYLRLLMTEVAWTKDELKEALDDVTLPRLKAFIPQLLSRLHIEALLHGNITKQAALGVMQMVEDTLIEHAH--TKPLLPSQLVRYREVQLPDRGWFVY--QQRNEVHNNCGIEIYYQTDMQSTSENMFLELFCQIISEPCFNTLRTKEQLGYIVFSGPRRANGIQGLRFIIQ 851          

HSP 2 Score: 31.9574 bits (71), Expect = 5.890e-31
Identity = 14/28 (50.00%), Postives = 20/28 (71.43%), Query Frame = 3

Query:    3 LNEYAYYAQVAGLDYGINHTESGFEVTV 86
            LNEYAY A++AGL Y + +T  G  ++V
Sbjct:  604 LNEYAYAAELAGLSYDLQNTIYGMYLSV 631          

BLAST of EY664150 vs. ExPASy Swiss-Prot
Match: IDE_DROME (Insulin-degrading enzyme OS=Drosophila melanogaster GN=Ide PE=1 SV=4)

HSP 1 Score: 106.686 bits (265), Expect = 2.125e-23
Identity = 62/223 (27.80%), Postives = 109/223 (48.88%), Query Frame = 2

Query:   89 GYNHKLRILLETIFQKIAQFKVKPDRFSVIKEMVTKEYHNNKFLQPFQLAMYYCSLILQDQTWPWMEELEVLPHLEAEDLAKFVPMMLSRTFLECYIAGNIESNEAGSMIQYIEDVFFKGSNPICQPLFPSQHLTNRVVKLEKGKNYVYSNQGLNPSDENSCLVHYIQVHRDDFLMNVKLQLLALIAKQPAFHQLRTVEQLGYITALLQRNDFGIHGVQFIIQ 757
            G++ K  +LLE +   +  F +   RF ++KE   +   N K  QP+Q ++YY +L+L +  W  ME L+ +  +  + +  F      R   EC+I GN+   +A  +   + +   + +N    P+   Q L  R  KL  G +Y++  +  N   ++SC   Y+Q        N+ + L++ +  +P +  LRT EQLGYI     R   G +G++ I+Q
Sbjct:  606 GFSDKQVVLLEKLLDHLFDFSIDEKRFDILKEEYVRSLKNFKAEQPYQHSIYYLALLLTENAWANMELLDAMELVTYDRVLNFAKEFFQRLHTECFIFGNVTKQQATDIAGRV-NTRLEATNASKLPILARQMLKKREYKLLAGDSYLFEKE--NEFHKSSCAQLYLQCGAQTDHTNIMVNLVSQVLSEPCYDCLRTKEQLGYIVFSGVRKVNGANGIRIIVQ 825          

HSP 2 Score: 23.8682 bits (50), Expect = 2.125e-23
Identity = 10/28 (35.71%), Postives = 15/28 (53.57%), Query Frame = 3

Query:    3 LNEYAYYAQVAGLDYGINHTESGFEVTV 86
            LNEY Y A++A L   +     G + T+
Sbjct:  577 LNEYLYDAELASLKLSVMGKSCGIDFTI 604          

BLAST of EY664150 vs. ExPASy Swiss-Prot
Match: MU138_SCHPO (Putative zinc protease mug138 OS=Schizosaccharomyces pombe GN=mug138 PE=1 SV=1)

HSP 1 Score: 101.293 bits (251), Expect = 1.101e-21
Identity = 59/211 (27.96%), Postives = 108/211 (51.18%), Query Frame = 2

Query:   89 GYNHKLRILLETIFQKIAQFKVKPDRFSVIKEMVTKEYHNNKFLQPFQLAMYYCSLILQDQTWPWMEELEVLPHLEAEDLAKFVPMMLSRTFLECYIAGNIESNEAGSMIQYIEDVFFKGSNPICQPLFPSQHLTNRVVKLEKGKNYVYSNQGLNPSDENSCLVHYIQVHR-DDFLMNVKLQLLALIAKQPAFHQLRTVEQLGYITALLQR 718
            G+  KL +LLE +   +   KV P RF ++K  + +E  +   L+ +  + +  + + +  +W   E  E +  ++  D++ F+  +L + FLE  + GN    +A ++I+  + +     +P  +P+F SQ    R + + +G NY+Y     N  ++NS +++ +Q+ + DD       +L   I K+P F  LRT EQLGYI   L R
Sbjct:  595 GFTDKLHVLLEKVVAMMRDLKVHPQRFEILKNRLEQELKDYDALEAYHRSNHVLTWLSEPHSWSNAELREAIKDVQVGDMSDFISDLLKQNFLESLVHGNYTEEDAKNLIESAQKLI----DP--KPVFASQLSRKRAIIVPEGGNYIYKTVVPNKEEKNSAIMYNLQISQLDDERSGALTRLARQIMKEPTFSILRTKEQLGYIVFTLVR 799          

HSP 2 Score: 23.483 bits (49), Expect = 1.101e-21
Identity = 9/23 (39.13%), Postives = 15/23 (65.22%), Query Frame = 3

Query:    3 LNEYAYYAQVAGLDYGINHTESG 71
            L EY+Y A +AGL + ++ +  G
Sbjct:  566 LGEYSYPASLAGLSFSLSPSTRG 588          

BLAST of EY664150 vs. ExPASy Swiss-Prot
Match: STE23_YEAST (A-factor-processing enzyme OS=Saccharomyces cerevisiae GN=STE23 PE=1 SV=2)

HSP 1 Score: 100.523 bits (249), Expect = 1.304e-20
Identity = 65/225 (28.89%), Postives = 104/225 (46.22%), Query Frame = 2

Query:   83 SGGYNHKLRILLETIFQKIAQFKVKPDRFSVIKEMVTKEYHNNKFLQPFQLAMYYCSLILQDQTWPWMEELEVLPHLEAEDLAKFVPMMLSRTFLECYIAGNIESNEAGSMIQYIEDVFFKGSNPICQPLFPSQHLTNRVVKLEKGKNYVYSNQGLNPSDENSCLVHYIQVHRDDFLMNVKLQLLALIAKQPAFHQLRTVEQLGYITALLQRNDFGIHGVQFIIQ 757
            + G+N KL ILL    Q +  F+ K DRF ++K+   +   N  +  P+     Y + I+ +++W   E+L+V   L  E L  F+P +    + E  I GNI+  EA  +   I+ +     N I      +  L  R   L KGK + Y     +  + NSC+ H  Q+      ++    L A +  +P F  LRT EQLGY+      N+ G   ++ +IQ
Sbjct:  641 ASGFNEKLIILLTRFLQGVNSFEPKKDRFEILKDKTIRHLKNLLYEVPYSQMSNYYNAIINERSWSTAEKLQVFEKLTFEQLINFIPTIYEGVYFETLIHGNIKHEEALEVDSLIKSLI---PNNIHNLQVSNNRL--RSYLLPKGKTFRYETALKDSQNVNSCIQHVTQLDVYSEDLSALSGLFAQLIHEPCFDTLRTKEQLGYVVFSSSLNNHGTANIRILIQ 860          

BLAST of EY664150 vs. ExPASy Swiss-Prot
Match: NRDC_HUMAN (Nardilysin OS=Homo sapiens GN=NRD1 PE=1 SV=2)

HSP 1 Score: 87.8113 bits (216), Expect = 8.746e-17
Identity = 68/219 (31.05%), Postives = 106/219 (48.40%), Query Frame = 2

Query:   89 GYNHKLRILLETIFQKIAQFKVKPDRFSVIKEMVTKEYHNNKFLQPFQLAMYYCSLILQDQTWPWMEELEVL-PHLEAEDLAKFVPMMLSRTFLECYIAGNIESNEAGSMIQYIED-VFFKGSNPICQPLFPSQHLTNRVVKLEKGKNYVYSNQGLNPSDENSCLVHYIQVHRDDFLMNVKLQLLALIAKQPAFHQLRTVEQLGYITALLQRNDFGIHG 739
            G+NHKL +L + I   +A+F   P  F++I E + K Y  N  ++P  LA     LIL+   W  +++ + L   L  E L  FV    S+ F+E  + GN+ S E+   ++Y+ D + FK       PL     +  +VV+L  G +++   + LN  D NS +  Y Q           ++LL +  ++P F  LRT + LGY      RN  GI G
Sbjct:  764 GFNHKLPLLFQLIIDYLAEFNSTPAVFTMITEQLKKTYF-NILIKPETLAKDVRLLILEYARWSMIDKYQALMDGLSLESLLSFVKEFKSQLFVEGLVQGNVTSTESMDFLKYVVDKLNFK-------PLEQEMPVQFQVVELPSG-HHLCKVKALNKGDANSEVTVYYQSGTRSLREYTLMELLVMHMEEPCFDFLRTKQTLGYHVYPTCRNTSGILG 973          

BLAST of EY664150 vs. ExPASy Swiss-Prot
Match: NRDC_PONAB (Nardilysin OS=Pongo abelii GN=NRD1 PE=2 SV=1)

HSP 1 Score: 85.5001 bits (210), Expect = 4.341e-16
Identity = 67/219 (30.59%), Postives = 106/219 (48.40%), Query Frame = 2

Query:   89 GYNHKLRILLETIFQKIAQFKVKPDRFSVIKEMVTKEYHNNKFLQPFQLAMYYCSLILQDQTWPWMEELEVL-PHLEAEDLAKFVPMMLSRTFLECYIAGNIESNEAGSMIQYIED-VFFKGSNPICQPLFPSQHLTNRVVKLEKGKNYVYSNQGLNPSDENSCLVHYIQVHRDDFLMNVKLQLLALIAKQPAFHQLRTVEQLGYITALLQRNDFGIHG 739
            G+NHKL +L + I   +A+F   P  F++I E + K Y  N  ++P  LA     LIL+   W  +++ + L   L  E L  FV    S+ F+E  + GN+ S E+   ++Y+ D + FK       PL     +  +VV+L  G +++   + LN  D NS +  Y Q           ++LL +  ++P F  LRT + LGY      R+  GI G
Sbjct:  766 GFNHKLPLLFQLIVDYLAEFNSTPAVFTMITEQLKKTYF-NILIKPETLAKDVRLLILEYARWSMIDKYQALMDGLSLESLLSFVKEFKSQLFVEGLVQGNVTSTESMDFLKYVVDKLNFK-------PLEQEMPVQFQVVELPSG-HHLCKVKALNKGDANSEVTVYYQSGTRSLREYTLMELLVMHMEEPCFDFLRTKQTLGYHVYPTCRSTSGILG 975          

BLAST of EY664150 vs. ExPASy Swiss-Prot
Match: NRDC_RAT (Nardilysin OS=Rattus norvegicus GN=Nrd1 PE=2 SV=1)

HSP 1 Score: 83.5741 bits (205), Expect = 1.649e-15
Identity = 66/218 (30.28%), Postives = 103/218 (47.25%), Query Frame = 2

Query:   89 GYNHKLRILLETIFQKIAQFKVKPDRFSVIKEMVTKEYHNNKFLQPFQLAMYYCSLILQDQTWPWMEELEVL-PHLEAEDLAKFVPMMLSRTFLECYIAGNIESNEAGSMIQYIEDVFFKGSNPICQPLFPSQHLTNRVVKLEKGKNYVYSNQGLNPSDENSCLVHYIQVHRDDFLMNVKLQLLALIAKQPAFHQLRTVEQLGYITALLQRNDFGIHG 739
            G+NHKL +L + I   + +F   P  F++I E + K Y  N  ++P  LA     LIL+   W  +++   L   L  E L  FV    S+ F+E  + GN+ S E+   ++Y+ D      N +  PL     +  +VV+L  G +++   + LN  D NS +  Y Q           ++LL +  ++P F  LRT + LGY      RN  GI G
Sbjct:  776 GFNHKLPLLFQLIIDYLTEFSSTPAVFTMITEQLKKTYF-NILIKPETLAKDVRLLILEYSRWSMIDKYRALMDGLSLESLLNFVKDFKSQLFVEGLVQGNVTSTESMDFLRYVVDKL----NFV--PLEREMPVQFQVVELPSG-HHLCKVRALNKGDANSEVTVYYQSGTRSLREYTLMELLVMHMEEPCFDFLRTKQTLGYHVYPTCRNTSGILG 985