EY675498

BLAST of EY675498 vs. ExPASy Swiss-Prot
Match: NPC1_MOUSE (Niemann-Pick C1 protein OS=Mus musculus GN=Npc1 PE=1 SV=1)

HSP 1 Score: 108.997 bits (271), Expect = 1.723e-23
Identity = 56/110 (50.91%), Postives = 78/110 (70.91%), Query Frame = 2

Query:   11 GIAVEPLVHLVHAFLVS-HGPRNQRSQKALSTMGASVFSGITLTKLVGVIVLCFARSEIFVVYYFQMYLALVIIGFLHGLVFLPVILSLFGP----PSRHIIIEKQQADE 325
            GI+VE   H+  AF +S  G R  R+++AL+ MG+SVFSGITLTK  G++VL FA+S+IF ++YF+MYLA+V++G  HGL+FLPV+LS  GP      RH   E+ +  E
Sbjct: 1162 GISVEFCSHITRAFTMSTKGSRVSRAEEALAHMGSSVFSGITLTKFGGIVVLAFAKSQIFEIFYFRMYLAMVLLGATHGLIFLPVLLSYIGPSVNKAKRHTTYERYRGTE 1271          

BLAST of EY675498 vs. ExPASy Swiss-Prot
Match: NPC1_HUMAN (Niemann-Pick C1 protein OS=Homo sapiens GN=NPC1 PE=1 SV=2)

HSP 1 Score: 108.997 bits (271), Expect = 1.723e-23
Identity = 53/92 (57.61%), Postives = 73/92 (79.35%), Query Frame = 2

Query:   11 GIAVEPLVHLVHAFLVS-HGPRNQRSQKALSTMGASVFSGITLTKLVGVIVLCFARSEIFVVYYFQMYLALVIIGFLHGLVFLPVILSLFGP 283
            GI+VE   H+  AF VS  G R +R+++AL+ MG+SVFSGITLTK  G++VL FA+S+IF ++YF+MYLA+V++G  HGL+FLPV+LS  GP
Sbjct: 1162 GISVEFCSHITRAFTVSMKGSRVERAEEALAHMGSSVFSGITLTKFGGIVVLAFAKSQIFQIFYFRMYLAMVLLGATHGLIFLPVLLSYIGP 1253          

BLAST of EY675498 vs. ExPASy Swiss-Prot
Match: NPC1_PIG (Niemann-Pick C1 protein OS=Sus scrofa GN=NPC1 PE=2 SV=1)

HSP 1 Score: 107.071 bits (266), Expect = 6.547e-23
Identity = 52/92 (56.52%), Postives = 72/92 (78.26%), Query Frame = 2

Query:   11 GIAVEPLVHLVHAFLVS-HGPRNQRSQKALSTMGASVFSGITLTKLVGVIVLCFARSEIFVVYYFQMYLALVIIGFLHGLVFLPVILSLFGP 283
            GI+VE   H+  AF +S  G R  R+++AL+ MG+SVFSGITLTK  G++VL FA+S+IF ++YF+MYLA+V++G  HGL+FLPV+LS  GP
Sbjct: 1161 GISVEFCSHITRAFTLSTKGSRVDRAEEALAHMGSSVFSGITLTKFGGIVVLAFAKSQIFQIFYFRMYLAIVLLGATHGLIFLPVLLSYIGP 1252          

BLAST of EY675498 vs. ExPASy Swiss-Prot
Match: NPC1_YEAST (Niemann-Pick type C-related protein 1 OS=Saccharomyces cerevisiae GN=NCR1 PE=1 SV=1)

HSP 1 Score: 90.8929 bits (224), Expect = 4.856e-18
Identity = 48/97 (49.48%), Postives = 65/97 (67.01%), Query Frame = 2

Query:   11 GIAVEPLVHLVHAFLV----SHGPRNQRSQKALSTMGASVFSGITLTKLVGVIVLCFARSEIFVVYYFQMYLALVIIGFLHGLVFLPVILSLFGPPS 289
            G+ VE  VH+V +F V    +    N R   +L+T+G SV  GITLTK +GV VL FA+S+IF V+YF+M+  L+I+  LH L+FLP +LSLFG  S
Sbjct: 1064 GLGVEFCVHIVRSFTVVPSETKKDANSRVLYSLNTIGESVIKGITLTKFIGVCVLAFAQSKIFDVFYFRMWFTLIIVAALHALLFLPALLSLFGGES 1160          

BLAST of EY675498 vs. ExPASy Swiss-Prot
Match: NPCL1_MOUSE (Niemann-Pick C1-like protein 1 OS=Mus musculus GN=Npc1l1 PE=2 SV=1)

HSP 1 Score: 87.4261 bits (215), Expect = 5.368e-17
Identity = 43/118 (36.44%), Postives = 80/118 (67.80%), Query Frame = 2

Query:    2 TRPGIAVEPLVHLVHAFLVSHGP-RNQRSQKALSTMGASVFSGITLTKLVGVIVLCFARSEIFVVYYFQMYLALVIIGFLHGLVFLPVILSLFGPP-SRHIIIEKQQADEPSTSSNLS 349
            T  G++VE + H+  +F VS  P R +R++ A   MG++VF+G+ +T   G+++L FA++++  +++F++ L + ++G LHGLVFLPV+LS  GP  ++ +++E++ A E +  S  S
Sbjct: 1174 TAVGMSVEFVSHITRSFAVSTKPTRLERAKDATIFMGSAVFAGVAMTNFPGILILGFAQAQLIQIFFFRLNLLITLLGLLHGLVFLPVVLSYLGPDVNQALVLEEKLATEAAMVSEPS 1291          

BLAST of EY675498 vs. ExPASy Swiss-Prot
Match: NPCL1_RAT (Niemann-Pick C1-like protein 1 OS=Rattus norvegicus GN=Npc1l1 PE=1 SV=1)

HSP 1 Score: 87.0409 bits (214), Expect = 7.011e-17
Identity = 42/118 (35.59%), Postives = 77/118 (65.25%), Query Frame = 2

Query:    2 TRPGIAVEPLVHLVHAFLVSHGP-RNQRSQKALSTMGASVFSGITLTKLVGVIVLCFARSEIFVVYYFQMYLALVIIGFLHGLVFLPVILSLFGPPSRHIIIEKQQ-------ADEPS 331
            T  G++VE + H+  +F VS  P R +R++ A   MG++VF+G+ +T   G+++L FA++++  +++F++ L + ++G LHGLVFLPV+LS  GP     ++++++       A EPS
Sbjct: 1174 TAVGMSVEFVSHITRSFAVSTKPTRLERAKDATVFMGSAVFAGVAMTNFPGILILGFAQAQLIQIFFFRLNLLITLLGLLHGLVFLPVVLSYLGPDVNQALVQEEKLASEAAVAPEPS 1291          

BLAST of EY675498 vs. ExPASy Swiss-Prot
Match: NPCL1_HUMAN (Niemann-Pick C1-like protein 1 OS=Homo sapiens GN=NPC1L1 PE=2 SV=1)

HSP 1 Score: 84.7297 bits (208), Expect = 3.480e-16
Identity = 40/107 (37.38%), Postives = 77/107 (71.96%), Query Frame = 2

Query:   11 GIAVEPLVHLVHAFLVSHGPR-NQRSQKALSTMGASVFSGITLTKLVGVIVLCFARSEIFVVYYFQMYLALVIIGFLHGLVFLPVILSLFGPP-SRHIIIEKQQADE 325
            G++VE + H+  +F +S  P   +R+++A  +MG++VF+G+ +T L G++VL  A++++  +++F++ L + ++G LHGLVFLPVILS  GP  +  + +E+++A+E
Sbjct: 1203 GMSVEFVSHITRSFAISTKPTWLERAKEATISMGSAVFAGVAMTNLPGILVLGLAKAQLIQIFFFRLNLLITLLGLLHGLVFLPVILSYVGPDVNPALALEQKRAEE 1309          

BLAST of EY675498 vs. ExPASy Swiss-Prot
Match: PTC2_MOUSE (Protein patched homolog 2 OS=Mus musculus GN=Ptch2 PE=2 SV=2)

HSP 1 Score: 77.0258 bits (188), Expect = 7.256e-14
Identity = 40/101 (39.60%), Postives = 60/101 (59.41%), Query Frame = 2

Query:   11 GIAVEPLVHLVHAFLVSHGPRNQRSQKALSTMGASVFSGITLTKLVGVIVLCFARSEIFVVYYFQMYLALVIIGFLHGLVFLPVILSLFGPPSRHIIIEKQ 313
            GI VE  VH+   FL SHG RN R+  AL    A V  G   T L+G+++L  +  +  + Y+F +   L ++G LHGL+ LPV+LS+ GPP + + + K+
Sbjct: 1027 GIGVEFTVHVALGFLTSHGSRNLRAASALEQTFAPVTDGAVST-LLGLLMLAGSNFDFIIRYFFVVLTVLTLLGLLHGLLLLPVLLSILGPPPQVVQVYKE 1126          

BLAST of EY675498 vs. ExPASy Swiss-Prot
Match: PTC1_CAEEL (Protein patched homolog 1 OS=Caenorhabditis elegans GN=ptc-1 PE=1 SV=2)

HSP 1 Score: 73.559 bits (179), Expect = 8.022e-13
Identity = 39/94 (41.49%), Postives = 60/94 (63.83%), Query Frame = 2

Query:    2 TRPGIAVEPLVHLVHAFLVSHGPRNQRSQKALSTMGASVFSGITLTKLVGVIVLCFARSEIFVVYYFQMYLALVIIGFLHGLVFLPVILSLFGP 283
            T  GI VE  VH+V +FL + G R+QR+  A+  +   V  G + + L+G+++L F+  E  V Y+F +  AL+ IG ++GL+ LPV+LS FGP
Sbjct: 1243 TAVGIGVEFTVHVVVSFLTALGTRSQRTSSAVDRVFVPVIHG-SFSTLLGILMLGFSEFEFVVKYFFIVMTALICIGIINGLILLPVLLSWFGP 1335          

BLAST of EY675498 vs. ExPASy Swiss-Prot
Match: PTC2_HUMAN (Protein patched homolog 2 OS=Homo sapiens GN=PTCH2 PE=2 SV=2)

HSP 1 Score: 72.7886 bits (177), Expect = 1.368e-12
Identity = 40/104 (38.46%), Postives = 59/104 (56.73%), Query Frame = 2

Query:   11 GIAVEPLVHLVHAFLVSHGPRNQRSQKALSTMGASVFSGITLTKLVGVIVLCFARSEIFVVYYFQMYLALVIIGFLHGLVFLPVILSLFGPPSRHIIIEKQQAD 322
            GI VE  VH+   FL + G RN R+  AL    A V  G  ++ L+G+++L  +  +  V Y+F     L ++G LHGLV LPV+LS+ GPP   I + K+  +
Sbjct: 1027 GIGVEFTVHVALGFLTTQGSRNLRAAHALEHTFAPVTDG-AISTLLGLLMLAGSHFDFIVRYFFAALTVLTLLGLLHGLVLLPVLLSILGPPPEVIQMYKESPE 1129