EY675486

BLAST of EY675486 vs. ExPASy Swiss-Prot
Match: NPC1_MOUSE (Niemann-Pick C1 protein OS=Mus musculus GN=Npc1 PE=1 SV=1)

HSP 1 Score: 112.079 bits (279), Expect = 5.145e-24
Identity = 56/109 (51.38%), Postives = 79/109 (72.48%), Query Frame = 3

Query:    3 IAVESCVHLVHAFLVS-HGNRNQRSQKALSTMGASVFSGITLTKLVGVIVLCFARSEIFVVYYFQMYLALVIIGFLHGLVFLPVILSLFGP----PSRHIIIEKQQADE 314
            I+VE C H+  AF +S  G+R  R+++AL+ MG+SVFSGITLTK  G++VL FA+S+IF ++YF+MYLA+V++G  HGL+FLPV+LS  GP      RH   E+ +  E
Sbjct: 1163 ISVEFCSHITRAFTMSTKGSRVSRAEEALAHMGSSVFSGITLTKFGGIVVLAFAKSQIFEIFYFRMYLAMVLLGATHGLIFLPVLLSYIGPSVNKAKRHTTYERYRGTE 1271          

BLAST of EY675486 vs. ExPASy Swiss-Prot
Match: NPC1_HUMAN (Niemann-Pick C1 protein OS=Homo sapiens GN=NPC1 PE=1 SV=2)

HSP 1 Score: 112.079 bits (279), Expect = 5.145e-24
Identity = 53/91 (58.24%), Postives = 74/91 (81.32%), Query Frame = 3

Query:    3 IAVESCVHLVHAFLVS-HGNRNQRSQKALSTMGASVFSGITLTKLVGVIVLCFARSEIFVVYYFQMYLALVIIGFLHGLVFLPVILSLFGP 272
            I+VE C H+  AF VS  G+R +R+++AL+ MG+SVFSGITLTK  G++VL FA+S+IF ++YF+MYLA+V++G  HGL+FLPV+LS  GP
Sbjct: 1163 ISVEFCSHITRAFTVSMKGSRVERAEEALAHMGSSVFSGITLTKFGGIVVLAFAKSQIFQIFYFRMYLAMVLLGATHGLIFLPVLLSYIGP 1253          

BLAST of EY675486 vs. ExPASy Swiss-Prot
Match: NPC1_PIG (Niemann-Pick C1 protein OS=Sus scrofa GN=NPC1 PE=2 SV=1)

HSP 1 Score: 110.153 bits (274), Expect = 1.955e-23
Identity = 52/91 (57.14%), Postives = 73/91 (80.22%), Query Frame = 3

Query:    3 IAVESCVHLVHAFLVS-HGNRNQRSQKALSTMGASVFSGITLTKLVGVIVLCFARSEIFVVYYFQMYLALVIIGFLHGLVFLPVILSLFGP 272
            I+VE C H+  AF +S  G+R  R+++AL+ MG+SVFSGITLTK  G++VL FA+S+IF ++YF+MYLA+V++G  HGL+FLPV+LS  GP
Sbjct: 1162 ISVEFCSHITRAFTLSTKGSRVDRAEEALAHMGSSVFSGITLTKFGGIVVLAFAKSQIFQIFYFRMYLAIVLLGATHGLIFLPVLLSYIGP 1252          

BLAST of EY675486 vs. ExPASy Swiss-Prot
Match: NPC1_YEAST (Niemann-Pick type C-related protein 1 OS=Saccharomyces cerevisiae GN=NCR1 PE=1 SV=1)

HSP 1 Score: 93.9745 bits (232), Expect = 1.450e-18
Identity = 48/96 (50.00%), Postives = 66/96 (68.75%), Query Frame = 3

Query:    3 IAVESCVHLVHAFLV----SHGNRNQRSQKALSTMGASVFSGITLTKLVGVIVLCFARSEIFVVYYFQMYLALVIIGFLHGLVFLPVILSLFGPPS 278
            + VE CVH+V +F V    +  + N R   +L+T+G SV  GITLTK +GV VL FA+S+IF V+YF+M+  L+I+  LH L+FLP +LSLFG  S
Sbjct: 1065 LGVEFCVHIVRSFTVVPSETKKDANSRVLYSLNTIGESVIKGITLTKFIGVCVLAFAQSKIFDVFYFRMWFTLIIVAALHALLFLPALLSLFGGES 1160          

BLAST of EY675486 vs. ExPASy Swiss-Prot
Match: NPCL1_MOUSE (Niemann-Pick C1-like protein 1 OS=Mus musculus GN=Npc1l1 PE=2 SV=1)

HSP 1 Score: 82.0333 bits (201), Expect = 5.702e-15
Identity = 40/114 (35.09%), Postives = 76/114 (66.67%), Query Frame = 3

Query:    3 IAVESCVHLVHAFLVS-HGNRNQRSQKALSTMGASVFSGITLTKLVGVIVLCFARSEIFVVYYFQMYLALVIIGFLHGLVFLPVILSLFGPP-SRHIIIEKQQADEPSTSSNLS 338
            ++VE   H+  +F VS    R +R++ A   MG++VF+G+ +T   G+++L FA++++  +++F++ L + ++G LHGLVFLPV+LS  GP  ++ +++E++ A E +  S  S
Sbjct: 1178 MSVEFVSHITRSFAVSTKPTRLERAKDATIFMGSAVFAGVAMTNFPGILILGFAQAQLIQIFFFRLNLLITLLGLLHGLVFLPVVLSYLGPDVNQALVLEEKLATEAAMVSEPS 1291          

BLAST of EY675486 vs. ExPASy Swiss-Prot
Match: NPCL1_RAT (Niemann-Pick C1-like protein 1 OS=Rattus norvegicus GN=Npc1l1 PE=1 SV=1)

HSP 1 Score: 81.6481 bits (200), Expect = 7.447e-15
Identity = 39/114 (34.21%), Postives = 73/114 (64.04%), Query Frame = 3

Query:    3 IAVESCVHLVHAFLVS-HGNRNQRSQKALSTMGASVFSGITLTKLVGVIVLCFARSEIFVVYYFQMYLALVIIGFLHGLVFLPVILSLFGPPSRHIIIEKQQ-------ADEPS 320
            ++VE   H+  +F VS    R +R++ A   MG++VF+G+ +T   G+++L FA++++  +++F++ L + ++G LHGLVFLPV+LS  GP     ++++++       A EPS
Sbjct: 1178 MSVEFVSHITRSFAVSTKPTRLERAKDATVFMGSAVFAGVAMTNFPGILILGFAQAQLIQIFFFRLNLLITLLGLLHGLVFLPVVLSYLGPDVNQALVQEEKLASEAAVAPEPS 1291          

BLAST of EY675486 vs. ExPASy Swiss-Prot
Match: NPCL1_HUMAN (Niemann-Pick C1-like protein 1 OS=Homo sapiens GN=NPC1L1 PE=2 SV=1)

HSP 1 Score: 79.337 bits (194), Expect = 3.696e-14
Identity = 38/106 (35.85%), Postives = 74/106 (69.81%), Query Frame = 3

Query:    3 IAVESCVHLVHAFLVS-HGNRNQRSQKALSTMGASVFSGITLTKLVGVIVLCFARSEIFVVYYFQMYLALVIIGFLHGLVFLPVILSLFGPP-SRHIIIEKQQADE 314
            ++VE   H+  +F +S      +R+++A  +MG++VF+G+ +T L G++VL  A++++  +++F++ L + ++G LHGLVFLPVILS  GP  +  + +E+++A+E
Sbjct: 1204 MSVEFVSHITRSFAISTKPTWLERAKEATISMGSAVFAGVAMTNLPGILVLGLAKAQLIQIFFFRLNLLITLLGLLHGLVFLPVILSYVGPDVNPALALEQKRAEE 1309          

BLAST of EY675486 vs. ExPASy Swiss-Prot
Match: PTC2_MOUSE (Protein patched homolog 2 OS=Mus musculus GN=Ptch2 PE=2 SV=2)

HSP 1 Score: 76.2554 bits (186), Expect = 3.129e-13
Identity = 39/100 (39.00%), Postives = 60/100 (60.00%), Query Frame = 3

Query:    3 IAVESCVHLVHAFLVSHGNRNQRSQKALSTMGASVFSGITLTKLVGVIVLCFARSEIFVVYYFQMYLALVIIGFLHGLVFLPVILSLFGPPSRHIIIEKQ 302
            I VE  VH+   FL SHG+RN R+  AL    A V  G   T L+G+++L  +  +  + Y+F +   L ++G LHGL+ LPV+LS+ GPP + + + K+
Sbjct: 1028 IGVEFTVHVALGFLTSHGSRNLRAASALEQTFAPVTDGAVST-LLGLLMLAGSNFDFIIRYFFVVLTVLTLLGLLHGLLLLPVLLSILGPPPQVVQVYKE 1126          

BLAST of EY675486 vs. ExPASy Swiss-Prot
Match: PTC2_HUMAN (Protein patched homolog 2 OS=Homo sapiens GN=PTCH2 PE=2 SV=2)

HSP 1 Score: 72.0182 bits (175), Expect = 5.901e-12
Identity = 39/103 (37.86%), Postives = 59/103 (57.28%), Query Frame = 3

Query:    3 IAVESCVHLVHAFLVSHGNRNQRSQKALSTMGASVFSGITLTKLVGVIVLCFARSEIFVVYYFQMYLALVIIGFLHGLVFLPVILSLFGPPSRHIIIEKQQAD 311
            I VE  VH+   FL + G+RN R+  AL    A V  G  ++ L+G+++L  +  +  V Y+F     L ++G LHGLV LPV+LS+ GPP   I + K+  +
Sbjct: 1028 IGVEFTVHVALGFLTTQGSRNLRAAHALEHTFAPVTDG-AISTLLGLLMLAGSHFDFIVRYFFAALTVLTLLGLLHGLVLLPVLLSILGPPPEVIQMYKESPE 1129          

BLAST of EY675486 vs. ExPASy Swiss-Prot
Match: PTC1_DANRE (Protein patched homolog 1 OS=Danio rerio GN=ptch1 PE=2 SV=1)

HSP 1 Score: 72.0182 bits (175), Expect = 5.901e-12
Identity = 38/92 (41.30%), Postives = 57/92 (61.96%), Query Frame = 3

Query:    3 IAVESCVHLVHAFLVSHGNRNQRSQKALSTMGASVFSGITLTKLVGVIVLCFARSEIFVVYYFQMYLALVIIGFLHGLVFLPVILSLFGPPS 278
            I VE  VH+   FL + G+RN RS  A+  M A V  G  ++ L+GV++L  +  +  + Y+F +   L ++G L+GLV LPV+LSL GPP+
Sbjct: 1081 IGVEFTVHIALGFLTAIGDRNTRSAVAMEHMFAPVIDG-AISTLLGVLMLAGSEFDFIMRYFFAVLAILTLLGILNGLVLLPVLLSLMGPPA 1171