CX069869

BLAST of CX069869 vs. ExPASy Swiss-Prot
Match: S6PD_MALDO (NADP-dependent D-sorbitol-6-phosphate dehydrogenase OS=Malus domestica GN=S6PDH PE=2 SV=1)

HSP 1 Score: 320.857 bits (821), Expect = 5.009e-87
Identity = 150/232 (64.66%), Postives = 184/232 (79.31%), Query Frame = 2

Query:    2 WNSDHGHVLEACKDSXXXXXXXXXXXXXVHFPVATKHTGVGTTDSALDEDGVLEIDTTISLETTWHAMEDLVSMGLVRSIGISNYDIFLTRDCLAYSKVKPVVNQFETHPYFQRDSLVKFCQKHGICVTAHTPLGGAVANTEWFGTVSCLDDPVLKGLAEKYKRTVAQTVLRWGIQRNTAVIPKTSKLERLEENFKVFDFELSKEDMDVIKSIDRKYRTNQPARFWGIDLFA 697
            WNSDHGHV+EACK+S             VH+P+ TKH  +G T S L ED VL+ID TISL+ TW  ME  VS+GLVRSIG+SNY++FLTRDCLAYSK+KP V+QFETHPYFQRDSLVKFC KHG+  TAHTPLGGA AN + FG+VS LDDPVL  +A+KY ++VAQ  LRWGIQR TAVIPK+SK++RL+EN +V +F+LS EDM +I SIDRKYRT+ P++ WG+D++A
Sbjct:   79 WNSDHGHVVEACKNSLEKLQIDYLDLYLVHYPMPTKHNAIGKTASLLGEDKVLDIDVTISLQQTWEGMEKTVSLGLVRSIGLSNYELFLTRDCLAYSKIKPAVSQFETHPYFQRDSLVKFCMKHGVLPTAHTPLGGAAANKDMFGSVSPLDDPVLNDVAKKYGKSVAQICLRWGIQRKTAVIPKSSKIQRLKENLEVLEFQLSDEDMQLIYSIDRKYRTSLPSKTWGLDVYA 310          

BLAST of CX069869 vs. ExPASy Swiss-Prot
Match: ALRB_DICDI (Aldose reductase B OS=Dictyostelium discoideum GN=alrB PE=3 SV=2)

HSP 1 Score: 164.851 bits (416), Expect = 4.594e-40
Identity = 89/234 (38.03%), Postives = 129/234 (55.13%), Query Frame = 2

Query:    2 WNSDH--GHVLEACKDSXXXXXXXXXXXXXVHFPVATKHTGV-GTTDSALDEDGVLEIDTTISLETTWHAMEDLVSMGLVRSIGISNYDIFLTRDCLAYSKVKPVVNQFETHPYFQRDSLVKFCQKHGICVTAHTPLGGAVANTEWFGTVSCLDDPVLKGLAEKYKRTVAQTVLRWGIQRNTAVIPKTSKLERLEENFKVFDFELSKEDMDVIKSIDRKYRTNQPARFWGIDLF 694
            WNS H    V + C+ +             +H+P+A ++    GTT   L +     +   +S+  TW  ME LV  GLV+SIG+SN+++    D L Y+K+KP +NQ E HPY  + +L  FC ++GI +TA++PLG         G    L +  LK +A+K+ +TVA  + +W  QR    IPK+S   R+ ENF +FDF+LS EDMD I S++   RT  PA F  I LF
Sbjct:   85 WNSCHHASLVRKHCEKTLEDLGLEYLDLYLIHWPIAFENADPSGTTTQPLRDSDGEPVLAAVSIRETWQEMEKLVEYGLVKSIGVSNFNVQNLVDLLTYAKIKPAINQVEVHPYLSQPNLKYFCDRYGIVLTAYSPLGQ--------GKCDLLSNETLKSIADKHNKTVANVIFKWLNQRGIVTIPKSSNPARIIENFNIFDFQLSNEDMDKINSLNSNLRTCTPANFCKIPLF 310          

BLAST of CX069869 vs. ExPASy Swiss-Prot
Match: ALRA_DICDI (Aldose reductase A OS=Dictyostelium discoideum GN=alrA PE=2 SV=1)

HSP 1 Score: 159.073 bits (401), Expect = 2.521e-38
Identity = 86/234 (36.75%), Postives = 130/234 (55.56%), Query Frame = 2

Query:    2 WNSDHG--HVLEACKDSXXXXXXXXXXXXXVHFPVATKHTGVGTTDSALDEDGVLEIDTTISLETTWHAMEDLVSMGLVRSIGISNYDIFLTRDCLAYSKVKPVVNQFETHPYFQRDSLVKFCQKHGICVTAHTPLG-GAVANTEWFGTVSCLDDPVLKGLAEKYKRTVAQTVLRWGIQRNTAVIPKTSKLERLEENFKVFDFELSKEDMDVIKSIDRKYRTNQPARFWGIDLF 694
            WN+ H   HV  A + +             VH+PVA ++T      S   ++ V       S+  TW  ME LV  GLV+SIG+SN+++    + L+Y+++KP  NQ E HP+  +  L KFC KH I +TA++PLG GA  + E  G +           A+KY +T+   + +W IQ+N +VIPK+S   R+ ENF +F+FE+ + DM  +  +D+  RT  PA+FWG+ LF
Sbjct:   81 WNTFHKKEHVRPALERTLSDLGLQYLDLYLVHWPVAFEYTSNDIQTSGSTQEFV-------SIRETWEEMEKLVDAGLVKSIGLSNFNVQGLMEVLSYARIKPAANQVELHPFLSQPELKKFCDKHNIHLTAYSPLGNGAFVDNEEVGAI-----------AKKYNKTIPNVLCKWAIQKNFSVIPKSSTPSRVAENFDLFNFEIEEADMLFLDKMDKNLRTCDPAKFWGVPLF 296          

BLAST of CX069869 vs. ExPASy Swiss-Prot
Match: ALRC_DICDI (Aldose reductase C OS=Dictyostelium discoideum GN=alrC PE=3 SV=1)

HSP 1 Score: 155.606 bits (392), Expect = 2.787e-37
Identity = 83/234 (35.47%), Postives = 129/234 (55.13%), Query Frame = 2

Query:    2 WNSDHGH--VLEACKDSXXXXXXXXXXXXXVHFPVATKHTG-VGTTDSALDEDGVLEIDTTISLETTWHAMEDLVSMGLVRSIGISNYDIFLTRDCLAYSKVKPVVNQFETHPYFQRDSLVKFCQKHGICVTAHTPLGGAVANTEWFGTVSCLDDPVLKGLAEKYKRTVAQTVLRWGIQRNTAVIPKTSKLERLEENFKVFDFELSKEDMDVIKSIDRKYRTNQPARFWGIDLF 694
            WNS H    V++ C  +             +H+P+A +++  +G T   L +     I   +S+  TW  ME LV +GLV+SIG+SN+++    D L Y+K+KPVVNQ E HPY  +  L ++C K+ I + A++PLG         G      + +LK +A KYK++VA  + +W  QR  A IPK+    R+ ENF +FDF+LS +D++ I S++   RT  P  F+G   +
Sbjct:   93 WNSCHNSNLVVKHCVKTIEDLGIGYLDLYLIHWPIAFENSNPLGLTIEPLRDQNGNPIIAPVSIRETWQEMEKLVELGLVKSIGVSNFNVQNLVDLLTYAKIKPVVNQVEIHPYLTQFKLQEYCDKYEIKLVAYSPLGQ--------GKCDFFSNKILKSIAGKYKKSVANVIFKWLNQRGIAAIPKSGNHSRIIENFNIFDFQLSNDDIEKINSLNANIRTCSPITFFGTPFY 318          

BLAST of CX069869 vs. ExPASy Swiss-Prot
Match: ALDR_PIG (Aldose reductase OS=Sus scrofa GN=AKR1B1 PE=1 SV=2)

HSP 1 Score: 149.058 bits (375), Expect = 2.608e-35
Identity = 88/222 (39.64%), Postives = 125/222 (56.31%), Query Frame = 2

Query:    2 WNSDHGH--VLEACKDSXXXXXXXXXXXXXVHFPVATKHTGVGTTDSALDEDGVLEIDTTISLETTWHAMEDLVSMGLVRSIGISNYDIFLTRDCLAYS--KVKPVVNQFETHPYFQRDSLVKFCQKHGICVTAHTPLGGAVANTEWFGTVSCLDDPVLKGLAEKYKRTVAQTVLRWGIQRNTAVIPKTSKLERLEENFKVFDFELSKEDMDVIKSIDRKYR 655
            W +DH    V  AC+ +             +H+P   K    G     LD DG +  D +  +ET W AME+LV  GLV++IG+SN++       L     K KP VNQ E HPY  ++ L+++C+  GI VTA++PLG            S L+DP +K +A KY +T AQ ++R+ +QRN  VIPK+   ER+ ENF+VFDFELS EDM+ + S +R +R
Sbjct:   80 WCTDHEKNLVKGACQTTLRDLKLDYLDLYLIHWPTGFKP---GKDPFPLDGDGNVVPDESDFVET-WEAMEELVDEGLVKAIGVSNFNHLQVEKILNKPGLKYKPAVNQIEVHPYLTQEKLIEYCKSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKYNKTTAQVLIRFPMQRNLIVIPKSVTPERIAENFQVFDFELSPEDMNTLLSYNRNWR 297          

BLAST of CX069869 vs. ExPASy Swiss-Prot
Match: A1A1A_DANRE (Alcohol dehydrogenase [NADP+] A OS=Danio rerio GN=akr1a1a PE=2 SV=2)

HSP 1 Score: 148.288 bits (373), Expect = 4.449e-35
Identity = 86/220 (39.09%), Postives = 119/220 (54.09%), Query Frame = 2

Query:    2 WNSDH--GHVLEACKDSXXXXXXXXXXXXXVHFPVATKHTGVGTTDSALDEDGVLEIDTTISLETTWHAMEDLVSMGLVRSIGISNYDIFLTRDCLAYSKVKPVVNQFETHPYFQRDSLVKFCQKHGICVTAHTPLGGAVANTEWFGTVSCLDDPVLKGLAEKYKRTVAQTVLRWGIQRNTAVIPKTSKLERLEENFKVFDFELSKEDMDVIKSIDRKYR 655
            WN+ H    V EAC+ S             +H+P+A    G G        DG ++ D T     TW AME LV  GL ++IG+SN++     D L+ +K KPVVNQ E HPY  +  LV  C    + VTA++PLG         G    LDDP + G+A+ Y +T AQ ++RW IQR    IPK+    R+++N +VFDF+LS EDM +I+S +R  R
Sbjct:   81 WNTKHHPDDVEEACRRSLSDLRLSYLDLYLIHWPMAF---GRGDELIPRHPDGTIQYDDT-HYRDTWAAMEKLVDQGLAKAIGLSNFNAKQIDDILSIAKHKPVVNQVECHPYLVQAELVSHCWSRNLTVTAYSPLGSPDRPWVTPGEALLLDDPRVVGIAKSYNKTPAQVIIRWHIQRGVVCIPKSVTPSRIKQNIEVFDFKLSDEDMRLIESFNRNER 296          

BLAST of CX069869 vs. ExPASy Swiss-Prot
Match: ALDR_BOVIN (Aldose reductase OS=Bos taurus GN=AKR1B1 PE=1 SV=1)

HSP 1 Score: 147.902 bits (372), Expect = 5.811e-35
Identity = 87/217 (40.09%), Postives = 121/217 (55.76%), Query Frame = 2

Query:   11 DHGHVLEACKDSXXXXXXXXXXXXXVHFPVATKHTGVGTTDSALDEDGVLEIDTTISLETTWHAMEDLVSMGLVRSIGISNYDIFLTRDCLAYS--KVKPVVNQFETHPYFQRDSLVKFCQKHGICVTAHTPLGGAVANTEWFGTVSCLDDPVLKGLAEKYKRTVAQTVLRWGIQRNTAVIPKTSKLERLEENFKVFDFELSKEDMDVIKSIDRKYR 655
            D   V  AC+ +             +H+P   K    G     LDEDG + I +      TW AME+LV  GLV++IG+SN++       L     K KP VNQ E HPY  ++ L+++C   GI VTA++PLG            S L+DP +K +A+KY +T AQ ++R+ IQRN  VIPK+   ER+ ENF+VFDFEL KEDM+ + S +R +R
Sbjct:   84 DKDLVKGACQKTLSDLKLDYLDLYLIHWPTGFKP---GKDFFPLDEDGNV-IPSEKDFVDTWTAMEELVDEGLVKAIGVSNFNHLQVEKILNKPGLKYKPAVNQIECHPYLTQEKLIQYCNSKGIVVTAYSPLGSPDRPWAKPEDPSILEDPRIKAIADKYNKTTAQVLIRFPIQRNLIVIPKSVTPERIAENFQVFDFELDKEDMNTLLSYNRDWR 296          

BLAST of CX069869 vs. ExPASy Swiss-Prot
Match: ALDR_HUMAN (Aldose reductase OS=Homo sapiens GN=AKR1B1 PE=1 SV=3)

HSP 1 Score: 147.517 bits (371), Expect = 7.589e-35
Identity = 90/221 (40.72%), Postives = 125/221 (56.56%), Query Frame = 2

Query:   11 DHGHVLEACKDSXXXXXXXXXXXXXVHFPVATKHTGVGTTDSALDEDG-VLEIDTTISLETTWHAMEDLVSMGLVRSIGISNY-----DIFLTRDCLAYSKVKPVVNQFETHPYFQRDSLVKFCQKHGICVTAHTPLGGAVANTEWFGTVSCLDDPVLKGLAEKYKRTVAQTVLRWGIQRNTAVIPKTSKLERLEENFKVFDFELSKEDMDVIKSIDRKYR 655
            + G V  AC+ +             +H+P   K    G     LDE G V+  DT I    TW AME+LV  GLV++IGISN+     ++ L +  L Y   KP VNQ E HPY  ++ L+++CQ  GI VTA++PLG            S L+DP +K +A K+ +T AQ ++R+ +QRN  VIPK+   ER+ ENFKVFDFELS +DM  + S +R +R
Sbjct:   85 EKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKP---GKEFFPLDESGNVVPSDTNIL--DTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKY---KPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKHNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWR 297          

BLAST of CX069869 vs. ExPASy Swiss-Prot
Match: AKCL2_PIG (1,5-anhydro-D-fructose reductase OS=Sus scrofa GN=AKR1E2 PE=1 SV=2)

HSP 1 Score: 146.362 bits (368), Expect = 1.691e-34
Identity = 85/213 (39.91%), Postives = 121/213 (56.81%), Query Frame = 2

Query:   23 VLEACKDSXXXXXXXXXXXXXVHFPVATKHTGVGTTDSALDEDGVLEIDTTISLETTWHAMEDLVSMGLVRSIGISNYDIFLTRDCLAYS--KVKPVVNQFETHPYFQRDSLVKFCQKHGICVTAHTPLGGAVANTEWFGTVSCLDDPVLKGLAEKYKRTVAQTVLRWGIQRNTAVIPKTSKLERLEENFKVFDFELSKEDMDVIKSIDRKYR 655
            V  AC  S             +H+P+  K    G  D  +D  G++    T  L+T W AMEDLV  GLVR+IG+SN++       L     +VKPV NQ E HPY  +  L+ FCQ   + VTA+ PLGG+         V  L+DPV++ +A+K+ ++ AQ ++R+ IQRN  VIPK+   +R+ ENF+VFDFELS++DM  +  +DR  R
Sbjct:   80 VKSACTRSLKALKLQYLDLYLIHWPMGFKP---GEVDLPVDRSGMIVASNTDFLDT-WEAMEDLVIEGLVRAIGVSNFNHEQLERLLNKPNLRVKPVTNQIECHPYLTQKKLISFCQSRNVSVTAYRPLGGSSEG------VPLLEDPVIQTIAQKHGKSAAQILIRFQIQRNVIVIPKSVNPKRILENFQVFDFELSEQDMTDLLGLDRNLR 282          

BLAST of CX069869 vs. ExPASy Swiss-Prot
Match: ALDR_RABIT (Aldose reductase OS=Oryctolagus cuniculus GN=AKR1B1 PE=2 SV=3)

HSP 1 Score: 144.436 bits (363), Expect = 6.425e-34
Identity = 86/217 (39.63%), Postives = 120/217 (55.30%), Query Frame = 2

Query:   11 DHGHVLEACKDSXXXXXXXXXXXXXVHFPVATKHTGVGTTDSALDEDGVLEIDTTISLETTWHAMEDLVSMGLVRSIGISNYDIFLTRDCLAYS--KVKPVVNQFETHPYFQRDSLVKFCQKHGICVTAHTPLGGAVANTEWFGTVSCLDDPVLKGLAEKYKRTVAQTVLRWGIQRNTAVIPKTSKLERLEENFKVFDFELSKEDMDVIKSIDRKYR 655
            D   V  AC+ +             +H+P   KH   G+    LD  G +    T  L+T W AME LV  GLV+SIG+SN++       L     K KP VNQ E HPY  ++ L+++C   GI VTA++PLG            S L+DP +K +A+K+K+T AQ ++R+ +QRN  VIPK+    R+ ENF+VFDFELS EDM  + S +R +R
Sbjct:   85 DKSLVKGACQKTLNDLKLDYLDLYLIHWPTGFKH---GSEYFPLDAAGNVIPSDTDFLDT-WEAMEGLVDEGLVKSIGVSNFNHLQIERILNKPGLKYKPAVNQIECHPYLTQEKLIQYCHSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIADKHKKTTAQVLIRFPMQRNLVVIPKSVTPARIAENFQVFDFELSSEDMTTLLSYNRNWR 297