CX045923

BLAST of CX045923 vs. ExPASy Swiss-Prot
Match: DPYD_CAEEL (Dihydropyrimidine dehydrogenase [NADP+] OS=Caenorhabditis elegans GN=dpyd-1 PE=2 SV=2)

HSP 1 Score: 187.193 bits (474), Expect = 1.041e-46
Identity = 97/215 (45.12%), Postives = 135/215 (62.79%), Query Frame = 1

Query:  235 EPDLSITVNGLQMPNPFVIGSGPPGTNYTVMKRAFDEGWGAVVAKTVSLDAAKVINVTPRYARLRAGANGSAKGQIIG-----WENIELISDRPLETMLKEFKQLKALYPDKILIASIMEEYNKAAWEELIDRVEETGIDAIEVNFSCPHGMPERKMGAAVGQDCRLLEEVCGWINAKATVPVWAKMTPNITDITEPARVALRSGSEGVSAINTI 864
            E D+S+ + G++  NPF + S PP T+  + +RAF++GWG ++ KT  LD   V NV+PR  R      GS  G + G     + NIELIS++  E  L+  ++LK  +P KI+IASIM  YNKA W EL  + EE G D +E+N SCPHGM E+ MG A GQ   +++E+C W+ A   +P + KMTPNITD+ E AR A   G+ GV+A NT+
Sbjct:  544 EVDISVDMCGVKFENPFGLASAPPTTSGPMCRRAFEQGWGFILTKTYGLDKDLVTNVSPRIVR------GSTSGPLYGPNQGSFMNIELISEKSCEYWLQCIRELKRDHPTKIVIASIMCVYNKADWIELATKSEEAGADILELNLSCPHGMGEKGMGLACGQSPEIVKEICRWVRACVKIPFFPKMTPNITDVREIARAARDGGASGVTATNTV 752          

BLAST of CX045923 vs. ExPASy Swiss-Prot
Match: DPYD_MOUSE (Dihydropyrimidine dehydrogenase [NADP+] OS=Mus musculus GN=Dpyd PE=2 SV=1)

HSP 1 Score: 186.808 bits (473), Expect = 1.360e-46
Identity = 97/213 (45.54%), Postives = 130/213 (61.03%), Query Frame = 1

Query:  241 DLSITVNGLQMPNPFVIGSGPPGTNYTVMKRAFDEGWGAVVAKTVSLDAAKVINVTPRYARLRAGANGSAKGQIIG-----WENIELISDRPLETMLKEFKQLKALYPDKILIASIMEEYNKAAWEELIDRVEETGIDAIEVNFSCPHGMPERKMGAAVGQDCRLLEEVCGWINAKATVPVWAKMTPNITDITEPARVALRSGSEGVSAINTI 864
            D+S+ + GL+ PNPF + S  P T+  +++RAF+ GWG  + KT SLD   V NV+PR  R      G+  G + G     + NIELIS++          +LKA +PD ILIASIM  YNK+ W EL    E +G DA+E+N SCPHGM ER MG A GQD  L+  +C W+     VP +AK+TPN+TDI   AR A   G++GV+A NT+
Sbjct:  532 DISVEMAGLRFPNPFGLASATPATSTPMIRRAFEAGWGFALTKTFSLDKDIVTNVSPRIIR------GTTSGPLYGPGQSSFLNIELISEKTAAYWCHSVTELKADFPDNILIASIMCSYNKSDWMELSKMAEASGADALELNLSCPHGMGERGMGLACGQDPELVRNICRWVRQAVRVPFFAKLTPNVTDIVSIARAAKEGGADGVTATNTV 738          

BLAST of CX045923 vs. ExPASy Swiss-Prot
Match: DPYD_RAT (Dihydropyrimidine dehydrogenase [NADP+] OS=Rattus norvegicus GN=Dpyd PE=2 SV=1)

HSP 1 Score: 186.037 bits (471), Expect = 2.320e-46
Identity = 97/213 (45.54%), Postives = 129/213 (60.56%), Query Frame = 1

Query:  241 DLSITVNGLQMPNPFVIGSGPPGTNYTVMKRAFDEGWGAVVAKTVSLDAAKVINVTPRYARLRAGANGSAKGQIIG-----WENIELISDRPLETMLKEFKQLKALYPDKILIASIMEEYNKAAWEELIDRVEETGIDAIEVNFSCPHGMPERKMGAAVGQDCRLLEEVCGWINAKATVPVWAKMTPNITDITEPARVALRSGSEGVSAINTI 864
            D+S+ + GL+ PNPF + S  P T+  +++RAF+ GWG  + KT SLD   V NV+PR  R      G+  G + G     + NIELIS++          +LKA +PD ILIASIM  YNK  W EL    E +G DA+E+N SCPHGM ER MG A GQD  L+  +C W+     VP +AK+TPN+TDI   AR A   G++GV+A NT+
Sbjct:  532 DISVEMAGLRFPNPFGLASATPATSTPMIRRAFEAGWGFALTKTFSLDKDIVTNVSPRIIR------GTTSGPLYGPGQSSFLNIELISEKTAAYWCHSVTELKADFPDNILIASIMCSYNKNDWMELSKMAEASGADALELNLSCPHGMGERGMGLACGQDPELVRNICRWVRQSVRVPFFAKLTPNVTDIVSIARAAKEGGADGVTATNTV 738          

BLAST of CX045923 vs. ExPASy Swiss-Prot
Match: DPYD_DANRE (Dihydropyrimidine dehydrogenase [NADP+] OS=Danio rerio GN=dpyd PE=2 SV=1)

HSP 1 Score: 184.882 bits (468), Expect = 5.167e-46
Identity = 92/213 (43.19%), Postives = 132/213 (61.97%), Query Frame = 1

Query:  241 DLSITVNGLQMPNPFVIGSGPPGTNYTVMKRAFDEGWGAVVAKTVSLDAAKVINVTPRYARLRAGANGSAKGQIIG-----WENIELISDRPLETMLKEFKQLKALYPDKILIASIMEEYNKAAWEELIDRVEETGIDAIEVNFSCPHGMPERKMGAAVGQDCRLLEEVCGWINAKATVPVWAKMTPNITDITEPARVALRSGSEGVSAINTI 864
            D+S+ + G++ PNPF + S PP T+  +++RAF++GWG  + KT  LD   V NV+PR  R      G+  G I G     + NIELIS++      K   +LKA +P  I+IASIM  YN+A W EL    +E+  DA+E+N SCPHGM ER MG A GQD  L+  +C W+    ++P +AK+TPN+T+I + A  A   G++GV+A NT+
Sbjct:  532 DISVEMCGIKFPNPFGLASAPPTTSAAMIRRAFEQGWGFALTKTFGLDKDLVTNVSPRIVR------GTTSGHIFGPGQGSFLNIELISEKTAAYWCKSVAELKADFPKNIIIASIMCSYNQADWTELAKMAQESQADALELNLSCPHGMGERGMGLACGQDPELVRNICRWVRKATSIPFFAKLTPNVTNIVDIATAAYEGGADGVTATNTV 738          

BLAST of CX045923 vs. ExPASy Swiss-Prot
Match: DPYD_PONAB (Dihydropyrimidine dehydrogenase [NADP+] OS=Pongo abelii GN=DPYD PE=2 SV=1)

HSP 1 Score: 183.341 bits (464), Expect = 1.504e-45
Identity = 94/213 (44.13%), Postives = 131/213 (61.50%), Query Frame = 1

Query:  241 DLSITVNGLQMPNPFVIGSGPPGTNYTVMKRAFDEGWGAVVAKTVSLDAAKVINVTPRYARLRAGANGSAKGQIIG-----WENIELISDRPLETMLKEFKQLKALYPDKILIASIMEEYNKAAWEELIDRVEETGIDAIEVNFSCPHGMPERKMGAAVGQDCRLLEEVCGWINAKATVPVWAKMTPNITDITEPARVALRSGSEGVSAINTI 864
            D+S+ + GL+  NPF + S  P T+ ++++RAF+ GWG  + KT SLD   V NV+PR  R      G+  G + G     + NIELIS++      +   +LKA +PD I+IASIM  YNK  W EL  + E++G DA+E+N SCPHGM ER MG A GQD  L+  +C W+     +P +AK+TPN+TDI   AR A   G+ GV+A NT+
Sbjct:  532 DISVEMAGLKFINPFGLASATPATSTSMIRRAFEAGWGFALTKTFSLDKDIVTNVSPRIVR------GTTSGPMYGPGQSSFLNIELISEKTAAYWCQSVTELKADFPDNIVIASIMCSYNKNDWTELAKKSEDSGADALELNLSCPHGMGERGMGLACGQDPELVRNICRWVRQAVQIPFFAKLTPNVTDIVSIARAAKEGGANGVTATNTV 738          

BLAST of CX045923 vs. ExPASy Swiss-Prot
Match: DPYD_HUMAN (Dihydropyrimidine dehydrogenase [NADP+] OS=Homo sapiens GN=DPYD PE=1 SV=2)

HSP 1 Score: 182.956 bits (463), Expect = 1.964e-45
Identity = 94/213 (44.13%), Postives = 131/213 (61.50%), Query Frame = 1

Query:  241 DLSITVNGLQMPNPFVIGSGPPGTNYTVMKRAFDEGWGAVVAKTVSLDAAKVINVTPRYARLRAGANGSAKGQIIG-----WENIELISDRPLETMLKEFKQLKALYPDKILIASIMEEYNKAAWEELIDRVEETGIDAIEVNFSCPHGMPERKMGAAVGQDCRLLEEVCGWINAKATVPVWAKMTPNITDITEPARVALRSGSEGVSAINTI 864
            D+S+ + GL+  NPF + S  P T+ ++++RAF+ GWG  + KT SLD   V NV+PR  R      G+  G + G     + NIELIS++      +   +LKA +PD I+IASIM  YNK  W EL  + E++G DA+E+N SCPHGM ER MG A GQD  L+  +C W+     +P +AK+TPN+TDI   AR A   G+ GV+A NT+
Sbjct:  532 DISVEMAGLKFINPFGLASATPATSTSMIRRAFEAGWGFALTKTFSLDKDIVTNVSPRIIR------GTTSGPMYGPGQSSFLNIELISEKTAAYWCQSVTELKADFPDNIVIASIMCSYNKNDWTELAKKSEDSGADALELNLSCPHGMGERGMGLACGQDPELVRNICRWVRQAVQIPFFAKLTPNVTDIVSIARAAKEGGANGVTATNTV 738          

BLAST of CX045923 vs. ExPASy Swiss-Prot
Match: DPYD_DICDI (Dihydropyrimidine dehydrogenase [NADP+] OS=Dictyostelium discoideum GN=pyd1 PE=2 SV=1)

HSP 1 Score: 182.57 bits (462), Expect = 2.565e-45
Identity = 91/208 (43.75%), Postives = 131/208 (62.98%), Query Frame = 1

Query:  241 DLSITVNGLQMPNPFVIGSGPPGTNYTVMKRAFDEGWGAVVAKTVSLDAAKVINVTPRYARLRAGANGSAKGQIIGWENIELISDRPLETMLKEFKQLKALYPDKILIASIMEEYNKAAWEELIDRVEETGIDAIEVNFSCPHGMPERKMGAAVGQDCRLLEEVCGWINAKATVPVWAKMTPNITDITEPARVALRSGSEGVSAINTI 864
            D+S+ + G++ PNPF + S  P T+  +++R+F++GWG  V KT SLD   V NV+PR  R     +    GQ   + NIELIS++      K   +LK  +PD+I+IASIM  +NK  W +L    E +G D IE+N SCPHGM E+ MG A GQD  L+  +C W+ A   +P +AK+TPN+T+I E A+ A   G++GV+AINT+
Sbjct:  530 DISVEMCGMKFPNPFGLASATPATSAAMIRRSFEQGWGFAVTKTFSLDKDLVTNVSPRIVRGTTSGHHFGPGQG-AFLNIELISEKTCHYWCKAIGELKRDFPDRIVIASIMCGFNKEDWTQLAKMAEASGADGIELNLSCPHGMGEKGMGLACGQDTELVFHICQWVRAATRLPFFAKLTPNVTEIKEIAKAAHDGGADGVTAINTV 736          

BLAST of CX045923 vs. ExPASy Swiss-Prot
Match: DPYD_CAEBR (Probable dihydropyrimidine dehydrogenase [NADP+] OS=Caenorhabditis briggsae GN=dpyd-1 PE=3 SV=2)

HSP 1 Score: 182.57 bits (462), Expect = 2.565e-45
Identity = 94/215 (43.72%), Postives = 133/215 (61.86%), Query Frame = 1

Query:  235 EPDLSITVNGLQMPNPFVIGSGPPGTNYTVMKRAFDEGWGAVVAKTVSLDAAKVINVTPRYARLRAGANGSAKGQIIG-----WENIELISDRPLETMLKEFKQLKALYPDKILIASIMEEYNKAAWEELIDRVEETGIDAIEVNFSCPHGMPERKMGAAVGQDCRLLEEVCGWINAKATVPVWAKMTPNITDITEPARVALRSGSEGVSAINTI 864
            E D+S+ + G++  NPF + S PP T+  + +RAF++GWG ++ KT  LD   V NV+PR  R      GS  G + G     + NIELIS++  E  L+  ++LK  +P KI++ASIM  YNK  W EL  + E  G D +E+N SCPHGM E+ MG A GQ   +++E+C W+ A   +P + KMTPNITD+ E AR A   G+ GV+A NT+
Sbjct:  554 EVDISVDMCGVKFENPFGLASAPPTTSGPMCRRAFEQGWGFILTKTYGLDKDLVTNVSPRIVR------GSTSGPLYGPNQGSFMNIELISEKSCEYWLQCIRELKRDHPTKIVVASIMCVYNKEDWIELATKSEAAGADILELNLSCPHGMGEKGMGLACGQSPEIVKEICRWVRACVKIPFFPKMTPNITDVREIARAARDGGASGVTATNTV 762          

BLAST of CX045923 vs. ExPASy Swiss-Prot
Match: DPYD_PIG (Dihydropyrimidine dehydrogenase [NADP+] OS=Sus scrofa GN=DPYD PE=1 SV=1)

HSP 1 Score: 181.8 bits (460), Expect = 4.375e-45
Identity = 94/213 (44.13%), Postives = 131/213 (61.50%), Query Frame = 1

Query:  241 DLSITVNGLQMPNPFVIGSGPPGTNYTVMKRAFDEGWGAVVAKTVSLDAAKVINVTPRYARLRAGANGSAKGQIIG-----WENIELISDRPLETMLKEFKQLKALYPDKILIASIMEEYNKAAWEELIDRVEETGIDAIEVNFSCPHGMPERKMGAAVGQDCRLLEEVCGWINAKATVPVWAKMTPNITDITEPARVALRSGSEGVSAINTI 864
            D+S+ + GL+  NPF + S  P T+ ++++RAF+ GWG  + KT SLD   V NV+PR  R      G+  G + G     + NIELIS++      +   +LKA +PD I+IASIM  YNK  W EL  + E +G DA+E+N SCPHGM ER MG A GQD  L+  +C W+     +P +AK+TPN+TDI   AR A   G++GV+A NT+
Sbjct:  532 DISVEMAGLKFINPFGLASAAPTTSSSMIRRAFEAGWGFALTKTFSLDKDIVTNVSPRIVR------GTTSGPMYGPGQSSFLNIELISEKTAAYWCQSVTELKADFPDNIVIASIMCSYNKNDWMELSRKAEASGADALELNLSCPHGMGERGMGLACGQDPELVRNICRWVRQAVQIPFFAKLTPNVTDIVSIARAAKEGGADGVTATNTV 738          

BLAST of CX045923 vs. ExPASy Swiss-Prot
Match: DPYD_BOVIN (Dihydropyrimidine dehydrogenase [NADP+] OS=Bos taurus GN=DPYD PE=1 SV=1)

HSP 1 Score: 175.637 bits (444), Expect = 3.135e-43
Identity = 91/213 (42.72%), Postives = 128/213 (60.09%), Query Frame = 1

Query:  241 DLSITVNGLQMPNPFVIGSGPPGTNYTVMKRAFDEGWGAVVAKTVSLDAAKVINVTPRYARLRAGANGSAKGQIIG-----WENIELISDRPLETMLKEFKQLKALYPDKILIASIMEEYNKAAWEELIDRVEETGIDAIEVNFSCPHGMPERKMGAAVGQDCRLLEEVCGWINAKATVPVWAKMTPNITDITEPARVALRSGSEGVSAINTI 864
            D+S+ +  L+  NPF + S  P T+ ++++RAF+ GW   + KT SLD   V NV+PR  R      G+  G + G     + NIELIS++      +   +LKA +PD I+IASIM  YN+  W EL  + E +G DA+E+N SCPHGM ER MG A GQD  L+  +C W+     +P +AK+TPN+TDI   AR A   G+ GV+A NT+
Sbjct:  532 DISVEMAALKFTNPFGLASATPTTSSSMIRRAFEAGWAFALTKTFSLDKDIVTNVSPRIIR------GTTSGPMYGPGQSSFLNIELISEKTAAYWCQSVTELKADFPDNIVIASIMCSYNRNDWMELSRKAEASGADALELNLSCPHGMGERGMGLACGQDPELVRNICRWVRQAVRIPFFAKLTPNVTDIVSIARAAKEGGANGVTATNTV 738