CX675252

BLAST of CX675252 vs. ExPASy Swiss-Prot
Match: MP2K1_DICDI (Dual specificity mitogen-activated protein kinase kinase 1 OS=Dictyostelium discoideum GN=mekA PE=1 SV=1)

HSP 1 Score: 153.295 bits (386), Expect = 1.528e-36
Identity = 86/197 (43.65%), Postives = 123/197 (62.44%), Query Frame = 1

Query:  226 ADESDHSEKTYRCASHEMRIFGAIGSGASSVVQRAVHIPTHRIIALKKINIFEKEK-RNQLLTEIRTLCEAPCNEGLVEFHGAFYMPDSGQISIALEYMDGGSLADILRMQKSIPEPILSSMFKKLLQGLSYLHGVRHLVHRDIKPANLLVNLXGRPKITDFGISAGLXNSIAMCATFVGTVTYMSPERIRNESYSY 813
            A+   H +        +++I   +G GA  VV+ A H  +   IALK I +  +E  R Q++ E++TL +      +V F+ AFY    G I IALE+M+ GSL+DI++   +IPEP+L  +  ++LQGL YLH   HL+HRDIKP+N+LVN  G  KI DFG+S  L ++++   T+VGTVTYMSPERI   SYS+
Sbjct:  275 ANNHPHYDTNLSYDLKDLKIIRVLGRGAGGVVKLAYHETSGTYIALKVITLDIQENIRKQIILELKTLHKTSYPY-IVSFYDAFYT--EGSIFIALEFMELGSLSDIMKKTSTIPEPVLGKIAFQVLQGLVYLHRKLHLIHRDIKPSNILVNNKGEAKIADFGVSGQLQHTLSKAVTWVGTVTYMSPERISGRSYSF 468          

BLAST of CX675252 vs. ExPASy Swiss-Prot
Match: M2K1_ORYSJ (Mitogen-activated protein kinase kinase 1 OS=Oryza sativa subsp. japonica GN=MEK1 PE=1 SV=1)

HSP 1 Score: 152.91 bits (385), Expect = 1.996e-36
Identity = 90/217 (41.47%), Postives = 130/217 (59.91%), Query Frame = 1

Query:  175 GVYNFNELGLQKCTSWLADESDHSE---KTYRCASHEMRIFGAIGSGASSVVQRAVHIPTHRIIALKKINI-FEKEKRNQLLTEIRTLCEAPCNEGLVEFHGAFYMPDSGQISIALEYMDGGSLADILRMQKSIPEPILSSMFKKLLQGLSYLHGVRHLVHRDIKPANLLVNLXGRPKITDFGISAGLXNSIAMCATFVGTVTYMSPERIRNESYSY 813
            G    N+ GLQ  +   ADE   +    +  + +  ++ +   IG G+  +VQ   H     + ALK I +  ++  R Q++ E++ + +A  N  +V  H +FY   +G I + LEYMD GSLADI++  K+I EP L+ + K++L+GL YLH  RH++HRDIKP+NLLVN  G  KITDFG+SA L +S+    TFVGT  YM+PERI   SY Y
Sbjct:   34 GELRLNQRGLQLISEETADEPQSTNLKVEDVQLSMDDLEMIQVIGKGSGGIVQLVRHKWVGTLYALKGIQMNIQEAVRKQIVQELK-INQATQNAHIVLCHQSFY--HNGVIYLVLEYMDRGSLADIIKQVKTILEPYLAVLCKQVLEGLLYLHHERHVIHRDIKPSNLLVNRKGEVKITDFGVSAVLASSMGQRDTFVGTYNYMAPERISGSSYDY 247          

BLAST of CX675252 vs. ExPASy Swiss-Prot
Match: M2K6_ARATH (Mitogen-activated protein kinase kinase 6 OS=Arabidopsis thaliana GN=MKK6 PE=1 SV=1)

HSP 1 Score: 150.984 bits (380), Expect = 7.584e-36
Identity = 82/196 (41.84%), Postives = 119/196 (60.71%), Query Frame = 1

Query:  232 ESDHSEKTYRCASHEMRIFGAIGSGASSVVQRAVHIPTHRIIALKKINI-FEKEKRNQLLTEIR-TLCEAPCNEGLVEFHGAFYMPDSGQISIALEYMDGGSLADILRMQKSIPEPILSSMFKKLLQGLSYLHGVRHLVHRDIKPANLLVNLXGRPKITDFGISAGLXNSIAMCATFVGTVTYMSPERIRNESYSY 813
            +SD  E  +   + ++     IG G+  VVQ   H    +  A+K I +  ++E R Q++ E++     + C   +V +H  ++   +G  S+ LEYMD GSLAD++R  K+I EP L+ + K++L GL YLH  RH++HRDIKP+NLLVN  G  KI+DFG+SA L +S+    TFVGT  YMSPERI   +Y Y
Sbjct:   55 QSDSKELDFEITAEDLETVKVIGKGSGGVVQLVRHKWVGKFFAMKVIQMNIQEEIRKQIVQELKINQASSQCPHVVVCYHSFYH---NGAFSLVLEYMDRGSLADVIRQVKTILEPYLAVVCKQVLLGLVYLHNERHVIHRDIKPSNLLVNHKGEVKISDFGVSASLASSMGQRDTFVGTYNYMSPERISGSTYDY 247          

BLAST of CX675252 vs. ExPASy Swiss-Prot
Match: M2K2_ARATH (Mitogen-activated protein kinase kinase 2 OS=Arabidopsis thaliana GN=MKK2 PE=1 SV=2)

HSP 1 Score: 150.984 bits (380), Expect = 7.584e-36
Identity = 82/172 (47.67%), Postives = 112/172 (65.12%), Query Frame = 1

Query:  295 IGSGASSVVQRAVHIPTHRIIALKKINI-FEKEKRNQLLTEIRTLCEAPCNEGLVEFHGAFYMPDSGQISIALEYMDGGSLADILRMQKSIPEPILSSMFKKLLQGLSYLHGVRHLVHRDIKPANLLVNLXGRPKITDFGISAGLXNSIAMCATFVGTVTYMSPERIRNESY 807
            IG G+S VVQ   H  T +  ALK I +  ++  R  +  E++    + C   LV  + +FY  D+G IS+ LEYMDGGSLAD L+  K+IP+  LS++F+++LQGL YLH  RH++HRD+KP+NLL+N  G  KITDFG+S  + N+  +  TFVGT  YMSPERI    Y
Sbjct:   76 IGKGSSGVVQLVQHKWTGQFFALKVIQLNIDEAIRKAIAQELKINQSSQC-PNLVTSYQSFY--DNGAISLILEYMDGGSLADFLKSVKAIPDSYLSAIFRQVLQGLIYLHHDRHIIHRDLKPSNLLINHRGEVKITDFGVSTVMTNTAGLANTFVGTYNYMSPERIVGNKY 244          

BLAST of CX675252 vs. ExPASy Swiss-Prot
Match: DSOR1_DROME (Dual specificity mitogen-activated protein kinase kinase dSOR1 OS=Drosophila melanogaster GN=Dsor1 PE=2 SV=2)

HSP 1 Score: 140.584 bits (353), Expect = 1.025e-32
Identity = 85/190 (44.74%), Postives = 116/190 (61.05%), Query Frame = 1

Query:  247 EKTYRCASHEMRIFGAIGSGASSVVQRAVHIPTHRIIALKKINIFEKEK-RNQLLTEIRTLCEAPCN-EGLVEFHGAFYMPDSGQISIALEYMDGGSLADILRMQKSIPEPILSSMFKKLLQGLSYLHGVRHLVHRDIKPANLLVNLXGRPKITDFGISAGLXNSIAMCATFVGTVTYMSPERIRNESYS 810
            EK    +  ++   G +GSG   VV +  H  TH I+A K I++  K   + Q+L E++ L E  CN   +V F+GAFY    G+ISI +EYMDGGSL  IL+    IPE IL  +   +L+GLSYL     ++HRD+KP+N+LVN  G  KI DFG+S  L +S  M  +FVGT +YMSPER++   YS
Sbjct:   77 EKIGELSDEDLEKLGELGSGNGGVVMKVRHTHTHLIMARKLIHLEVKPAIKKQILRELKVLHE--CNFPHIVGFYGAFY--SDGEISICMEYMDGGSLDLILKRAGRIPESILGRITLAVLKGLSYLRDNHAIIHRDVKPSNILVNSSGEIKICDFGVSGQLIDS--MANSFVGTRSYMSPERLQGTHYS 260          

BLAST of CX675252 vs. ExPASy Swiss-Prot
Match: M2K1_ARATH (Mitogen-activated protein kinase kinase 1 OS=Arabidopsis thaliana GN=MKK1 PE=1 SV=2)

HSP 1 Score: 137.887 bits (346), Expect = 6.644e-32
Identity = 76/180 (42.22%), Postives = 114/180 (63.33%), Query Frame = 1

Query:  274 EMRIFGAIGSGASSVVQRAVHIPTHRIIALKKINIFEKEKRNQLLT-EIRTLCEAPCNEGLVEFHGAFYMPDSGQISIALEYMDGGSLADILRMQKSIPEPILSSMFKKLLQGLSYLHGVRHLVHRDIKPANLLVNLXGRPKITDFGISAGLXNSIAMCATFVGTVTYMSPERIRNESYS 810
            ++ +   IG G+S  VQ   H  T +  ALK I +  +E   + ++ E+R    + C   LV  + +FY   +G +SI LE+MDGGSLAD+L+    +PE +LS++ K++L+GL Y+H  R ++HRD+KP+NLL+N  G  KITDFG+S  L ++ ++  +FVGT  YMSPERI    YS
Sbjct:   67 DLEVIKVIGKGSSGNVQLVKHKLTQQFFALKVIQLNTEESTCRAISQELRINLSSQCPY-LVSCYQSFY--HNGLVSIILEFMDGGSLADLLKKVGKVPENMLSAICKRVLRGLCYIHHERRIIHRDLKPSNLLINHRGEVKITDFGVSKILTSTSSLANSFVGTYPYMSPERISGSLYS 243          

BLAST of CX675252 vs. ExPASy Swiss-Prot
Match: MP2K2_CYPCA (Dual specificity mitogen-activated protein kinase kinase 2 OS=Cyprinus carpio GN=map2k2 PE=2 SV=1)

HSP 1 Score: 135.576 bits (340), Expect = 3.297e-31
Identity = 88/255 (34.51%), Postives = 138/255 (54.12%), Query Frame = 1

Query:   52 KKKLAPLFDAEKGFSAGSTLDPSDSYMLSDGGTVNLLSRSYGVYNFNELGLQKCTSWLADESDHSEKTYRCASHEMRIFGAIGSGASSVVQRAVHIPTHRIIALKKINIFEKEK-RNQLLTEIRTLCEAPCNEG-LVEFHGAFYMPDSGQISIALEYMDGGSLADILRMQKSIPEPILSSMFKKLLQGLSYLHGVRHLVHRDIKPANLLVNLXGRPKITDFGISAGLXNSIAMCATFVGTVTYMSPERIRNESYS 810
            K++  PL  A  G    + +D +          +  L R  G  + +E   ++  ++L  ++   E        +      +G+G   VV +  H P+  ++A K I++  K   RNQ++ E++ L E  CN   +V F+GAFY    G+ISI +E+MDGGSL  +L+  + IPE IL  +   +L+GL YL     ++HRD+KP+N+LVN  G  K+ DFG+S  L +S  M  +FVGT +YMSPER++   YS
Sbjct:    4 KRRPVPLIIAPTGEGQSTNIDAASE------ANLEALQRKLGELDLDEQQRKRLEAFLTQKAQVGE----LKDEDFDPICELGAGNGGVVHKVRHKPSRLVMARKLIHLEIKPAIRNQIIRELQVLHE--CNSPYIVGFYGAFY--SDGEISICMEHMDGGSLDQVLKEARRIPEEILGKVSIAVLRGLVYLREKHQIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDS--MANSFVGTRSYMSPERLQGTHYS 242          

BLAST of CX675252 vs. ExPASy Swiss-Prot
Match: MP2K2_RAT (Dual specificity mitogen-activated protein kinase kinase 2 OS=Rattus norvegicus GN=Map2k2 PE=2 SV=1)

HSP 1 Score: 135.191 bits (339), Expect = 4.307e-31
Identity = 79/174 (45.40%), Postives = 113/174 (64.94%), Query Frame = 1

Query:  295 IGSGASSVVQRAVHIPTHRIIALKKINIFEKEK-RNQLLTEIRTLCEAPCNEG-LVEFHGAFYMPDSGQISIALEYMDGGSLADILRMQKSIPEPILSSMFKKLLQGLSYLHGVRHLVHRDIKPANLLVNLXGRPKITDFGISAGLXNSIAMCATFVGTVTYMSPERIRNESYS 810
            +G+G   VV +A H P+  I+A K I++  K   RNQ++ E++ L E  CN   +V F+GAFY    G+ISI +E+MDGGSL  +L+  K IPE IL  +   +L+GL+YL     ++HRD+KP+N+LVN  G  K+ DFG+S  L +S  M  +FVGT +YMSPER++   YS
Sbjct:   78 LGAGNGGVVTKARHRPSGLIMARKLIHLEIKPAVRNQIIRELQVLHE--CNSPYIVGFYGAFY--SDGEISICMEHMDGGSLDQVLKEAKRIPEDILGKVSIAVLRGLAYLREKHQIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDS--MANSFVGTRSYMSPERLQGTHYS 245          

BLAST of CX675252 vs. ExPASy Swiss-Prot
Match: MP2K2_MOUSE (Dual specificity mitogen-activated protein kinase kinase 2 OS=Mus musculus GN=Map2k2 PE=1 SV=1)

HSP 1 Score: 134.806 bits (338), Expect = 5.625e-31
Identity = 79/174 (45.40%), Postives = 113/174 (64.94%), Query Frame = 1

Query:  295 IGSGASSVVQRAVHIPTHRIIALKKINIFEKEK-RNQLLTEIRTLCEAPCNEG-LVEFHGAFYMPDSGQISIALEYMDGGSLADILRMQKSIPEPILSSMFKKLLQGLSYLHGVRHLVHRDIKPANLLVNLXGRPKITDFGISAGLXNSIAMCATFVGTVTYMSPERIRNESYS 810
            +G+G   VV +A H P+  I+A K I++  K   RNQ++ E++ L E  CN   +V F+GAFY    G+ISI +E+MDGGSL  +L+  K IPE IL  +   +L+GL+YL     ++HRD+KP+N+LVN  G  K+ DFG+S  L +S  M  +FVGT +YMSPER++   YS
Sbjct:   78 LGAGNGGVVTKARHRPSGFIMARKLIHLEIKPAVRNQIIRELQVLHE--CNSPYIVGFYGAFY--SDGEISICMEHMDGGSLDQVLKEAKRIPEDILGKVSIAVLRGLAYLREKHQIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDS--MANSFVGTRSYMSPERLQGTHYS 245          

BLAST of CX675252 vs. ExPASy Swiss-Prot
Match: MP2K2_CHICK (Dual specificity mitogen-activated protein kinase kinase 2 OS=Gallus gallus GN=MAP2K2 PE=2 SV=1)

HSP 1 Score: 134.035 bits (336), Expect = 9.594e-31
Identity = 78/174 (44.83%), Postives = 112/174 (64.37%), Query Frame = 1

Query:  295 IGSGASSVVQRAVHIPTHRIIALKKINIFEKEK-RNQLLTEIRTLCEAPCNEG-LVEFHGAFYMPDSGQISIALEYMDGGSLADILRMQKSIPEPILSSMFKKLLQGLSYLHGVRHLVHRDIKPANLLVNLXGRPKITDFGISAGLXNSIAMCATFVGTVTYMSPERIRNESYS 810
            +G+G   VV +  H P+  I+A K I++  K   RNQ++ E++ L E  CN   +V F+GAFY    G+ISI +E+MDGGSL  +L+  K IPE IL  +   +L+GL+YL     ++HRD+KP+N+LVN  G  K+ DFG+S  L +S  M  +FVGT +YMSPER++   YS
Sbjct:   76 LGAGNGGVVTKVQHKPSGLIMARKLIHLEIKPAIRNQIIRELQVLHE--CNSPYIVGFYGAFY--SDGEISICMEHMDGGSLDQVLKEAKRIPEEILGKVSIAVLRGLAYLREKHQIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDS--MANSFVGTRSYMSPERLQGTHYS 243