CV885074

BLAST of CV885074 vs. ExPASy Swiss-Prot
Match: THAS_PIG (Thromboxane-A synthase OS=Sus scrofa GN=TBXAS1 PE=2 SV=1)

HSP 1 Score: 101.679 bits (252), Expect = 1.776e-32
Identity = 49/117 (41.88%), Postives = 75/117 (64.10%), Query Frame = -1

Query:  197 RETAKEVEIGGYRLPKGTWVWLALGVVAKDSKNFPEPDKFKPERFDPNCEEAKQRHPCAYLPFGIGPRACIGQKFAMQEIKLSLIHLYRNYVFRHSPDMENPLELEFGIILNFKHGV 547
            RE A++ E+ G R+P GT + +A+G +  D K++P P+ F PERF    +  +Q  P  YLPFG GPR+C+G +  + EIKL+L+H+ R + F   P+ + PL+LE    L+ K+GV
Sbjct:  413 REAARDCEVLGQRIPAGTVLEVAVGALHHDPKHWPHPETFDPERFTAEAQRLQQ--PFTYLPFGAGPRSCLGVQLGLLEIKLTLLHILRKFRFEACPETQVPLQLESKSALSPKNGV 527          

HSP 2 Score: 59.3066 bits (142), Expect = 1.776e-32
Identity = 29/78 (37.18%), Postives = 43/78 (55.13%), Query Frame = -2

Query:  568 TPDYISAVTYEHLLAGSATTSFALSSIVYLVAAHPEVENKLLAEIDGFGPRELVPTALDLQQKFPYLDQVIKEAMRIY 801
            T D +    +  L+AG    +  LS + YL+A +P+ + KLL E+D F  +   P    LQQ  PYLD V+ E +R+Y
Sbjct:  328 TVDEVVGQAFLFLIAGYEIITNTLSFVTYLLATNPDCQEKLLREVDDFSKKHPSPEHCSLQQGLPYLDMVLSETLRMY 405          

BLAST of CV885074 vs. ExPASy Swiss-Prot
Match: THAS_MOUSE (Thromboxane-A synthase OS=Mus musculus GN=Tbxas1 PE=2 SV=2)

HSP 1 Score: 95.1301 bits (235), Expect = 1.128e-31
Identity = 46/117 (39.32%), Postives = 72/117 (61.54%), Query Frame = -1

Query:  197 RETAKEVEIGGYRLPKGTWVWLALGVVAKDSKNFPEPDKFKPERFDPNCEEAKQRHPCAYLPFGIGPRACIGQKFAMQEIKLSLIHLYRNYVFRHSPDMENPLELEFGIILNFKHGV 547
            RE A++ E+ G R+P GT + +A+G +  D +++P P+ F PERF    E   QR P  YLPFG GPR+C+G +  +  +KL+++ +   + F  SP+ + PL+LE    L  K+GV
Sbjct:  412 REAAQDCEVLGQRIPAGTVLEIAVGALHHDPEHWPNPETFDPERF--TAEARLQRRPFTYLPFGAGPRSCLGVRLGLLVVKLTILQVLHKFRFEASPETQVPLQLESKSALGPKNGV 526          

HSP 2 Score: 63.1586 bits (152), Expect = 1.128e-31
Identity = 33/85 (38.82%), Postives = 46/85 (54.12%), Query Frame = -2

Query:  568 TESKNVFTPDYISAVTYEHLLAGSATTSFALSSIVYLVAAHPEVENKLLAEIDGFGPRELVPTALDLQQKFPYLDQVIKEAMRIY 822
            T +   FT D I    +  L+AG    +  LS I YL+A HP+ + +LL E+D F  +   P    LQ+  PYLD VI E +R+Y
Sbjct:  320 TSTSKPFTVDEIVGQAFLFLIAGHEVITNTLSFITYLLATHPDCQERLLKEVDLFMGKHPAPEYHSLQEGLPYLDMVISETLRMY 404          

BLAST of CV885074 vs. ExPASy Swiss-Prot
Match: THAS_BOVIN (Thromboxane-A synthase OS=Bos taurus GN=TBXAS1 PE=2 SV=1)

HSP 1 Score: 95.9005 bits (237), Expect = 1.913e-31
Identity = 46/117 (39.32%), Postives = 72/117 (61.54%), Query Frame = -1

Query:  197 RETAKEVEIGGYRLPKGTWVWLALGVVAKDSKNFPEPDKFKPERFDPNCEEAKQRHPCAYLPFGIGPRACIGQKFAMQEIKLSLIHLYRNYVFRHSPDMENPLELEFGIILNFKHGV 547
            R  A++ E+ G R+P G  +  A+G +  D +++P P+ F PERF    E  ++R P  YLPFG GPR+C+G +  + E+KL+L+H+ R + F   P+ + PL+LE    L  K+GV
Sbjct:  412 RVAAQDCEVLGQRIPAGAVLETAVGALHYDPEHWPNPENFNPERF--TAEAQQRRRPYTYLPFGAGPRSCLGVRLGLLELKLTLLHILRKFRFEACPETQVPLQLESKSALGPKNGV 526          

HSP 2 Score: 61.6178 bits (148), Expect = 1.913e-31
Identity = 31/76 (40.79%), Postives = 42/76 (55.26%), Query Frame = -2

Query:  568 DYISAVTYEHLLAGSATTSFALSSIVYLVAAHPEVENKLLAEIDGFGPRELVPTALDLQQKFPYLDQVIKEAMRIY 795
            D +    +  L+AG    +  LS   YL+A +PE + KLL E+D F    L P    LQ+  PYLD VIKE +R+Y
Sbjct:  329 DEVVGQAFIFLIAGYEIVTNTLSFATYLLATNPECQEKLLEEVDCFSKEHLAPEYCSLQEGLPYLDMVIKETLRMY 404          

BLAST of CV885074 vs. ExPASy Swiss-Prot
Match: THAS_MACFA (Thromboxane-A synthase OS=Macaca fascicularis GN=TBXAS1 PE=2 SV=2)

HSP 1 Score: 98.2117 bits (243), Expect = 2.491e-31
Identity = 48/118 (40.68%), Postives = 76/118 (64.41%), Query Frame = -1

Query:  197 RETAKEVEIGGYRLPKGTWVWLALGVVAKDSKNFPEPDKFKPERFDPNCEEAKQRH-PCAYLPFGIGPRACIGQKFAMQEIKLSLIHLYRNYVFRHSPDMENPLELEFGIILNFKHGV 547
            RE A++ E+ G R+P G  + +A+G +  D +++P P+ F PERF     EA+Q+H P  YLPFG GPR+C+G +  + E+KL+L+H+   + F+  P+ + PL+LE    L  K+GV
Sbjct:  412 REAAQDCEVLGQRIPAGAVLEMAVGALHHDPEHWPSPETFNPERFTA---EAQQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFQFQACPETQVPLQLESKSALGPKNGV 526          

HSP 2 Score: 58.9214 bits (141), Expect = 2.491e-31
Identity = 30/78 (38.46%), Postives = 44/78 (56.41%), Query Frame = -2

Query:  568 TPDYISAVTYEHLLAGSATTSFALSSIVYLVAAHPEVENKLLAEIDGFGPRELVPTALDLQQKFPYLDQVIKEAMRIY 801
            T D I    +  L+AG    +  LS   YL+A +P+ + KLL E+D F  + +VP    L++  PYLD VI E +R+Y
Sbjct:  327 TVDEIVGQAFIFLIAGYEIVTNTLSFATYLLATNPDCQEKLLREVDLFKEKHMVPEFCSLEEGLPYLDMVIAETLRMY 404          

BLAST of CV885074 vs. ExPASy Swiss-Prot
Match: THAS_HUMAN (Thromboxane-A synthase OS=Homo sapiens GN=TBXAS1 PE=1 SV=3)

HSP 1 Score: 98.2117 bits (243), Expect = 7.162e-31
Identity = 48/118 (40.68%), Postives = 76/118 (64.41%), Query Frame = -1

Query:  197 RETAKEVEIGGYRLPKGTWVWLALGVVAKDSKNFPEPDKFKPERFDPNCEEAKQRH-PCAYLPFGIGPRACIGQKFAMQEIKLSLIHLYRNYVFRHSPDMENPLELEFGIILNFKHGV 547
            RE A++ E+ G R+P G  + +A+G +  D +++P P+ F PERF     EA+Q+H P  YLPFG GPR+C+G +  + E+KL+L+H+   + F+  P+ + PL+LE    L  K+GV
Sbjct:  412 REAAQDCEVLGQRIPAGAVLEMAVGALHHDPEHWPSPETFNPERFTA---EARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFRFQACPETQVPLQLESKSALGPKNGV 526          

HSP 2 Score: 57.3806 bits (137), Expect = 7.162e-31
Identity = 29/78 (37.18%), Postives = 43/78 (55.13%), Query Frame = -2

Query:  568 TPDYISAVTYEHLLAGSATTSFALSSIVYLVAAHPEVENKLLAEIDGFGPRELVPTALDLQQKFPYLDQVIKEAMRIY 801
            T D I    +  L+AG    +  LS   YL+A +P+ + KLL E+D F  + + P    L++  PYLD VI E +R+Y
Sbjct:  327 TVDEIVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREVDVFKEKHMAPEFCSLEEGLPYLDMVIAETLRMY 404          

BLAST of CV885074 vs. ExPASy Swiss-Prot
Match: CP3AD_MOUSE (Cytochrome P450 3A13 OS=Mus musculus GN=Cyp3a13 PE=2 SV=1)

HSP 1 Score: 85.1149 bits (209), Expect = 3.494e-30
Identity = 41/100 (41.00%), Postives = 65/100 (65.00%), Query Frame = -1

Query:  233 EVEIGGYRLPKGTWVWLALGVVAKDSKNFPEPDKFKPERFDPNCEEAKQRHPCAYLPFGIGPRACIGQKFAMQEIKLSLIHLYRNYVFRHSPDMENPLEL 532
            +VEI G  +PKGT V +    + KD K +PEP++F+PERF    +++   +P  YLPFG GPR CIG +FA+  +K++L+ + +N+  +   + E PL+L
Sbjct:  380 DVEINGLFIPKGTVVMIPTFALHKDPKYWPEPEEFRPERFSKKNQDSI--NPYMYLPFGSGPRNCIGMRFALINMKVALVRVLQNFTVQPCKETEIPLKL 477          

HSP 2 Score: 68.1662 bits (165), Expect = 3.494e-30
Identity = 41/112 (36.61%), Postives = 62/112 (55.36%), Query Frame = -2

Query:  559 RMKESKQGSKDLLSLIVKARELET-ESKNVFTPDYISAVTYEHLLAGSATTSFALSSIVYLVAAHPEVENKLLAEIDGFGPRELVPTALDLQQKFPYLDQVIKEAMRIYLVS 891
            RMKE ++   D L L++ ++  +T ES    +   I A +   + AG  TTS ALS  +YL+A HP+V+ KL  EID   P +  P   D   +  YLD V+ E +R+Y ++
Sbjct:  260 RMKEKEKQRVDFLQLMINSQNYKTKESHKALSDVEIVAQSVIFIFAGYETTSSALSFALYLLAIHPDVQKKLQDEIDAALPNK-APATYDTLLQMEYLDMVVNETLRLYPIA 370          

BLAST of CV885074 vs. ExPASy Swiss-Prot
Match: THAS_RAT (Thromboxane-A synthase OS=Rattus norvegicus GN=Tbxas1 PE=2 SV=1)

HSP 1 Score: 87.4261 bits (215), Expect = 4.545e-30
Identity = 43/117 (36.75%), Postives = 70/117 (59.83%), Query Frame = -1

Query:  197 RETAKEVEIGGYRLPKGTWVWLALGVVAKDSKNFPEPDKFKPERFDPNCEEAKQRHPCAYLPFGIGPRACIGQKFAMQEIKLSLIHLYRNYVFRHSPDMENPLELEFGIILNFKHGV 547
            RE A++ E+ G  +P G+ + +A+G +  D +++P P+ F PERF    E   Q+ P  YLPFG GPR+C+G +  +  +KL+L+ +   + F   P+ + PL+LE    L  K+GV
Sbjct:  412 REAAQDCEVLGQHIPAGSVLEIAVGALHHDPEHWPNPETFDPERF--TAEARLQQKPFTYLPFGAGPRSCLGVRLGLLVVKLTLLQVLHKFRFEACPETQVPLQLESKSALCPKNGV 526          

HSP 2 Score: 65.4698 bits (158), Expect = 4.545e-30
Identity = 33/85 (38.82%), Postives = 48/85 (56.47%), Query Frame = -2

Query:  568 TESKNVFTPDYISAVTYEHLLAGSATTSFALSSIVYLVAAHPEVENKLLAEIDGFGPRELVPTALDLQQKFPYLDQVIKEAMRIY 822
            T +    T D I+   +  L+AG   T+  LS I YL+A HPE + +LL E+D F  +   P   +LQ+  PYLD V+ E +R+Y
Sbjct:  320 TSTAKPLTVDEIAGQAFLFLIAGHEITTNTLSFITYLLATHPECQERLLKEVDLFMEKHPAPEYCNLQEGLPYLDMVVAETLRMY 404          

BLAST of CV885074 vs. ExPASy Swiss-Prot
Match: CP3AF_CAVPO (Cytochrome P450 3A15 OS=Cavia porcellus GN=CYP3A15 PE=2 SV=1)

HSP 1 Score: 88.9669 bits (219), Expect = 1.004e-29
Identity = 46/111 (41.44%), Postives = 66/111 (59.46%), Query Frame = -1

Query:  215 RETAKEVEIGGYRLPKGTWVWLALGVVAKDSKNFPEPDKFKPERFDPNCEEAKQRHPCAYLPFGIGPRACIGQKFAMQEIKLSLIHLYRNYVFRHSPDMENPLELEFGIIL 547
            R + K+ EI G   PKGT V +    + +DSK +PEPD+F+PERF    +E     P  Y+PFG GPR CIG++ A+  +KL+LI L +N+ F    + + PL L    +L
Sbjct:  375 RMSKKDFEINGMSFPKGTLVMIPSFALHRDSKYWPEPDEFRPERFSKKNKE--NIDPYIYMPFGNGPRNCIGRRMALMNLKLALIRLLQNFSFYPCKETQIPLRLSSEALL 483          

HSP 2 Score: 62.7734 bits (151), Expect = 1.004e-29
Identity = 39/121 (32.23%), Postives = 67/121 (55.37%), Query Frame = -2

Query:  529 MKESKQGSKDLLSLIVKAREL-ETESKNVFTPDYISAVTYEHLLAGSATTSFALSSIVYLVAAHPEVENKLLAEIDGFGPRELVPTALDLQQKFPYLDQVIKEAMRIYLVSPLVVEKQQKK 888
            ++ +K+   + L +++ ++   +TES    +   I A +   + AG  T+S  LS I+Y +A HP+V+ KL  EID   P +  PT  D+  +  YLD V+ E +R+Y V+   +E+  KK
Sbjct:  261 LESNKKQRVNFLQMMLNSQNFKDTESHKALSDVEILAQSIIFIFAGYETSSSTLSCIMYSLATHPDVQKKLHQEIDKTLPNKAFPT-YDVMMEMEYLDMVVNETLRLYPVANR-IERMSKK 379          

BLAST of CV885074 vs. ExPASy Swiss-Prot
Match: CP3AC_CANFA (Cytochrome P450 3A12 OS=Canis familiaris GN=CYP3A12 PE=2 SV=1)

HSP 1 Score: 87.0409 bits (214), Expect = 8.291e-29
Identity = 42/105 (40.00%), Postives = 67/105 (63.81%), Query Frame = -1

Query:  233 RETAKEVEIGGYRLPKGTWVWLALGVVAKDSKNFPEPDKFKPERFDPNCEEAKQRHPCAYLPFGIGPRACIGQKFAMQEIKLSLIHLYRNYVFRHSPDMENPLEL 547
            R   K+VEI G  +PKGT V +    + +D   +PEP++F+PERF    +++   +P  YLPFG GPR CIG +FA+  +KL+L+ + +N+ F+   + + PL+L
Sbjct:  375 RVCKKDVEISGVFIPKGTVVMVPTFTLHRDQSLWPEPEEFRPERFSRKNKDSI--NPYTYLPFGTGPRNCIGMRFAIMNMKLALVRVLQNFSFKPCKETQIPLKL 477          

HSP 2 Score: 61.6178 bits (148), Expect = 8.291e-29
Identity = 39/118 (33.05%), Postives = 65/118 (55.08%), Query Frame = -2

Query:  559 KRMKESKQGSK-----DLLSLIVKAREL-ETESKNVFTPDYISAVTYEHLLAGSATTSFALSSIVYLVAAHPEVENKLLAEIDGFGPRELVPTALDLQQKFPYLDQVIKEAMRIYLVS 894
            +RMKES+   K     D L L++ ++   E ++    +   + A +   + AG  TTS +LS ++Y +A HP+V+ KL  EID   P + +PT  D   +  YLD V+ E +R+Y ++
Sbjct:  254 ERMKESRLKDKQKHRVDFLQLMINSQNSKEMDTHKALSDLELVAQSIIFIFAGYETTSTSLSFLMYELATHPDVQQKLQEEIDATFPNKALPT-YDALVQMEYLDMVLNETLRLYPIA 370          

BLAST of CV885074 vs. ExPASy Swiss-Prot
Match: CP3AL_CALJA (Cytochrome P450 3A21 OS=Callithrix jacchus GN=CYP3A21 PE=2 SV=1)

HSP 1 Score: 85.8853 bits (211), Expect = 1.405e-28
Identity = 48/125 (38.40%), Postives = 71/125 (56.80%), Query Frame = -1

Query:  215 HEDLSSIPISCR---ETAKEVEIGGYRLPKGTWVWLALGVVAKDSKNFPEPDKFKPERFDPNCEEAKQRHPCAYLPFGIGPRACIGQKFAMQEIKLSLIHLYRNYVFRHSPDMENPLELEFGIIL 580
            +E L   P++ R      K+VEI G  +PKG  V +    +  D K + EP+KF PERF  N ++     P  Y PFG GPR CIG +FA+  +KL+LI + +N+ F+   + + PL+L  G +L
Sbjct:  361 NETLRLFPLAMRLERVCKKDVEINGVFIPKGVVVMIPSYALHYDPKYWTEPEKFLPERFSKNNKD--NIDPYIYTPFGTGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLRLGGLL 483          

HSP 2 Score: 62.003 bits (149), Expect = 1.405e-28
Identity = 37/109 (33.94%), Postives = 59/109 (54.13%), Query Frame = -2

Query:  568 RMKESKQGSKDLLSLIVKAREL-ETESKNVFTPDYISAVTYEHLLAGSATTSFALSSIVYLVAAHPEVENKLLAEIDGFGPRELVPTALDLQQKFPYLDQVIKEAMRIY 891
            R+K++ +   D L L++ ++   ETES    +   + A +   + AG  TTS  LS I+Y +A HP+V+ KL  EID   P +  P   D   +  YLD V+ E +R++
Sbjct:  260 RLKDTHKHRVDFLQLMIDSQNSKETESDKALSDLELVAQSIIFIFAGYETTSSTLSFIMYELATHPDVQQKLQEEIDAVLPNK-APATYDTVLQMEYLDMVVNETLRLF 367