Query: 1 MSAFIKLEDSPMFQKQLFSMEESAEELKDRCQRLYKGCKKFTEALGVACSGDSAFADALEAFGGGHDDPVSVSIGGPVISKFINAFRELATYKELLRSQVEHVLINRLTEFLTVDLHDAKESRRRFDKSIHAYDQAREKFVSLKKNTRDDIVAELEEDLQNSKSAFEKSRFNLVSALTNIEAKKKYEFLESISAIMDVHLRYFKLGFDLLSKIEPYVHQVLTYAQQSKEVANVEQDKLAKRIQEFRTQAELDNLGVPVDVEHSVSADGIHVGGTVSYKNIEAVMRSSATGEVQTIKQGYLLKRSSNLRGDWKRRFFVLNSQGTLYYYRNKGIKSMGSH-HHYAGSADHNGGVFSRFRSRHYRSSSFNEDSLNCRTVDLRTSAIKMDAEDTDLRLCFRIISPVKTYTLQAETEADRMDWTSKITGVIASLLNSDFLQQLRPSAKHI--DGNDPFSTRDIPSLSSHCSLEDEVKANKSDSVSAILRQIPGNDLCAECSAPDPDWASLNLGILLCIECSGVHRNLGVHISKVRSLKLDVKVWEPTILDLFGSLGNAYCNSIWEGLLLLKDREVDKSNTTIPSVRKPCSKDVFHYKEQYIHAKYVEKLLVIRDTSDA--KSRTTSIWEAVKTQNLQEVYRLIVTSDANIINTTFDDVVGVDSYHRVDNTQYSEIDFHKVKKEENNGPAGCQRIKDSNDPGNCLQGGSLLHLACQCGNLVMLELLIQFGADINMRDFHGRTPLHHCISSKNFTFAKFLLRRGARPSIKDGGGLSSLERAMEMGAITDEELFILLAE 786
M+AFI+L+DSPMFQ Q+ S+E++A+ELKDRCQRLYKGCKK+ ALG AC GD+ FAD+LEAFGGG DDPVSVSIGGPV+SKFI+A ELATYKELLRSQVEHVLI+RLT F+TVDL +AKESRRRFDK+IH YDQARE+FVSLKKNTRDDIVAELEEDL+NSKSAFEKSRFNLV+AL N+EAKKKYEFLES+SAIMD HLRYFKLG+DL S++EPY+HQVLTYAQQSKE A VEQD+LAKRIQEFRTQAE+D L ++E S DGI V G SYKNI+AV++SSA GEVQTIKQGYLLKRSSNLRGDWKRRFFVLNSQG LYYYR KG K MGSH HH+ SA+ G+F RFRS+H R++S NED L CRTVDL TS IKMDAED+DLRLCFRIISP+KTYTLQAE +ADRMDW +KITG I SLLNS F + ++ D + ++ D+ +L SH + ED++K+N+ + VS+ILR +PGNDLCAECS+PDPDWASLNLG+LLCIECSGVHRNLGVHISKVRSLKLDVKVWEPTILDLF +LGNAYCNS+WEGLL L++ D +N I S+ KPC +D FH KE+YI AKYVEKL VIRD S A +R TSIWEAVK+ NLQEVYRLIV SD NI NTTFDDV VDSYH V+ Q S VK+ + P C R+K+SN+PGNCLQ SLLHLAC G+L+M+ELL+QFGADIN+RDFHGRTPLHHCISS + AKFLLRRGARP IKDGGGLSSLERAMEMGAITDEELFILLAE
Sbjct: 1 MAAFIRLDDSPMFQSQICSLEQTADELKDRCQRLYKGCKKYMAALGEACIGDTVFADSLEAFGGGTDDPVSVSIGGPVMSKFISALHELATYKELLRSQVEHVLIDRLTNFMTVDLQEAKESRRRFDKAIHVYDQARERFVSLKKNTRDDIVAELEEDLENSKSAFEKSRFNLVNALMNVEAKKKYEFLESVSAIMDAHLRYFKLGYDLFSQMEPYIHQVLTYAQQSKEQAKVEQDRLAKRIQEFRTQAEMDTLRASSNIEPSAPVDGIRVIGINSYKNIDAVIQSSANGEVQTIKQGYLLKRSSNLRGDWKRRFFVLNSQGALYYYRIKGTKPMGSHSHHFTRSAEPASGMFGRFRSKHNRAASLNEDVLGCRTVDLGTSIIKMDAEDSDLRLCFRIISPLKTYTLQAENDADRMDWINKITGAITSLLNSQFFDEPNQVTTNLETDKSAGGASCDVQTLDSHQNSEDDIKSNRIECVSSILRGVPGNDLCAECSSPDPDWASLNLGVLLCIECSGVHRNLGVHISKVRSLKLDVKVWEPTILDLFRNLGNAYCNSLWEGLLQLENARKDDANALITSISKPCPRDAFHRKEKYIQAKYVEKLWVIRDESVAAMPARATSIWEAVKSNNLQEVYRLIVMSDVNITNTTFDDVFHVDSYHHVE-AQDSNCSHDTVKRRYID-PTACDRMKNSNEPGNCLQCCSLLHLACHSGDLLMIELLLQFGADINLRDFHGRTPLHHCISSGKNSLAKFLLRRGARPLIKDGGGLSSLERAMEMGAITDEELFILLAE 789
Query: 1 MSAFIKLEDSPMFQKQLFSMEESAEELKDRCQRLYKGCKKFTEALGVACSGDSAFADALEAFGGGHDDPVSVSIGGPVISKFINAFRELATYKELLRSQVEHVLINRLTEFLTVDLHDAKESRRRFDKSIHAYDQAREKFVSLKKNTRDDIVAELEEDLQNSKSAFEKSRFNLVSALTNIEAKKKYEFLESISAIMDVHLRYFKLGFDLLSKIEPYVHQVLTYAQQSKEVANVEQDKLAKRIQEFRTQAELDNLGVPVDVEHSVSADGIHVGGTVSYKNIEAVMRSSATGEVQTIKQGYLLKRSSNLRGDWKRRFFVLNSQGTLYYYRNKGIKSMGSHHHYAGSADHNGGVFSRFRSRHYRSSSFNEDSLNCRTVDLRTSAIKMDAEDTDLRLCFRIISPVKTYTLQAETEADRMDWTSKITGVIASLLNSDFLQQLRPSAKHIDGNDPFS--TRDIPSLSSHCSLEDEVKANKSDSVSAILRQIPGNDLCAECSAPDPDWASLNLGILLCIECSGVHRNLGVHISKVRSLKLDVKVWEPTILDLFGSLGNAYCNSIWEGLLLLKDREVDKSNTTIPSVRKPCSKDVFHYKEQYIHAKYVEKLLVIRD--TSDAKSRTTSIWEAVKTQNLQEVYRLIVTSDANIINTTFDDVVGVDSYHRVDNTQYSEIDFHKVKKEENNGPAGCQRIKDSNDPGNCLQGGSLLHLACQCGNLVMLELLIQFGADINMRDFHGRTPLHHCISSKNFTFAKFLLRRGARPSIKDGGGLSSLERAMEMGAITDEELFILLAE 786
M+AFI LEDSPMFQK++ S+E+ +EE+ DRCQRLYKGCK F ALG AC+ D+ FA++LEAFGGGHDDPVSVSIGGPVISKFINAFRELATYKELLRSQVEHVLI+RL F+ VDL +AKESR+R+DK+IHAYDQ+REKFVSLKKNTR +I+ ELEED+QNSKSAFE+SRFNLVSAL NIEAKKKYEFLESISAIMD HLRYFKLG++LLS++EP++HQVLTYAQQSKE+AN EQDKLAKRIQEFRTQAE +++ ++E S SADGIHV G S+KNIEA+M S+A GEV IKQGYLLKRSS LRGDWKRRFFVL+SQGTLYYYRNK K +G H S +HN VF+RFRSRH R+SS E SL CR +DLRTS IKM+AEDTDLRLCFR+ISP+KTYTLQAE E DRMDW +KITGVIASLL + F+QQ P KH + ND S T + L H L D++K N++D VS++LR+IPGNDLCAECSAP+PDWASLNLGIL+CIECSGVHRNLGVHISKVRSL LDVKVWEPT+LDLF +LGNAYCNSIWEGLL+L++ VD+ + S+ KPC KDV KE+YI AKYVEKLLVIR+ S + S + IW+AVKT NL+E+YR IV SD NI+NTTFD+VVG++S H V +TQ S+ + H ++++++ PA C RIKDS DP NCLQG SLLHLAC GN VMLELL+QFGAD+N+RDFH RTPLHHCIS N+ AKFLLRRGA PS++DGGGLS LERAMEMGAITDEELF++LAE
Sbjct: 1 MAAFINLEDSPMFQKEICSLEQISEEMNDRCQRLYKGCKSFMAALGDACNADTTFAESLEAFGGGHDDPVSVSIGGPVISKFINAFRELATYKELLRSQVEHVLIDRLVHFMDVDLQNAKESRKRYDKAIHAYDQSREKFVSLKKNTRGNIIEELEEDMQNSKSAFERSRFNLVSALVNIEAKKKYEFLESISAIMDAHLRYFKLGYELLSQMEPFIHQVLTYAQQSKELANSEQDKLAKRIQEFRTQAEFNSIHASSNIEPSTSADGIHVVGMSSFKNIEAIMHSTAKGEVLIIKQGYLLKRSSRLRGDWKRRFFVLDSQGTLYYYRNKATKPVGFQHRSTASIEHNSSVFARFRSRHNRASSLGEGSLACRIIDLRTSTIKMEAEDTDLRLCFRVISPLKTYTLQAENETDRMDWVNKITGVIASLLKAHFMQQPYPGMKHPECNDYTSGTTCVVQQLDGHQRLGDDLKVNRADCVSSVLRKIPGNDLCAECSAPEPDWASLNLGILVCIECSGVHRNLGVHISKVRSLTLDVKVWEPTVLDLFHALGNAYCNSIWEGLLMLRNERVDEPSAFASSIEKPCPKDVIFCKEKYIQAKYVEKLLVIREASVSGSFSHASGIWQAVKTNNLREIYRHIVISDINIVNTTFDEVVGIESLHHVSDTQDSQFNSHTSERKQHD-PATCPRIKDSKDPENCLQGCSLLHLACHYGNPVMLELLLQFGADVNLRDFHHRTPLHHCISKGNYPLAKFLLRRGASPSVRDGGGLSVLERAMEMGAITDEELFVMLAE 789
Query: 1 MSAFIKLEDSPMFQKQLFSMEESAEELKDRCQRLYKGCKKFTEALGVACSGDSAFADALEAFGGGHDDPVSVSIGGPVISKFINAFRELATYKELLRSQVEHVLINRLTEFLTVDLHDAKESRRRFDKSIHAYDQAREKFVSLKKNTRDDIVAELEEDLQNSKSAFEKSRFNLVSALTNIEAKKKYEFLESISAIMDVHLRYFKLGFDLLSKIEPYVHQVLTYAQQSKEVANVEQDKLAKRIQEFRTQAELDNLGVPVDVEHSVSADGIHVGGTVSYKNIEAVMRSSAT-GEVQTIKQGYLLKRSSNLRGDWKRRFFVLNSQGTLYYYRNKGIKSMGSHHHYAGSADHNGGVFSRFRSRHYRSSSFNEDSLNCRTVDLRTSAIKMDAEDTDLRLCFRIISPVKTYTLQAETEADRMDWTSKITGVIASLLNSDFLQQLRPSAKHIDGND----PFSTRDIPSLSSHCSLEDEVKANKSD--SVSAILRQIPGNDLCAECSAPDPDWASLNLGILLCIECSGVHRNLGVHISKVRSLKLDVKVWEPTILDLFGSLGNAYCNSIWEGLLLLKDREVDKSNTTIPSVRKPCSKDVFHYKEQYIHAKYVEKLLVIRD--TSDAKSRTTSIWEAVKTQNLQEVYRLIVTSDANIINTTFDDVVGVDSYHRVDNTQYSEIDFHKVKKEENNGPAGCQRIKDSNDPGNCLQGGSLLHLACQCGNLVMLELLIQFGADINMRDFHGRTPLHHCISSKNFTFAKFLLRRGARPSIKDGGGLSSLERAMEMGAITDEELFILLAE 786
M AFIKL+DSPMFQKQ+FS+E++A+ELK+R QRLYKGCKKF ALG AC+ D AFAD+LEAFGGG DDPVSVSIGGP+ISKFINAFRELAT+KELLRSQVEHVLI+R+ F+TVDL DAKESR RFDK+I AYDQAREKFVSLKK+TR DIVAELEEDL NSKSAFEKSRFNLV+AL N+E KKK+EFLESISAIMD HLRYFKLG+D+LS +EP++HQVLTYAQQSKE+AN+EQDKLAKRIQEFRTQAELD+L ++E S DGIHV SYK IEA+M+S+A GEVQTIKQGYL KRSSNLRGDWKRRFFVL+S GTLYYYRNKG MGS H Y+GSA+ N GVFSRFR+RH RSSS NE+ L C T++LRTS IKMDA+DTDLRLCFRIISP+KTYTLQAE ADR+DW +K+ GVIASLLNS FLQQ P K+++ ND ++ +PSL SH S ED ++ N++D S+S +LR+IPGND+CAECSAPDPDWASLNLGILLCIECSGVHRNLGVHISKVRSL LDVKVWEPTILDLF +LGNAY NSIWEG LL+++ V +S+ + S+ KPC KD KE+YIHAKYVEKLLVIRD S S +T IW+AVK NL+EVYRLIVTSD NI+NT FDDV VD Y+ + + Q D HK+K++E + PA CQRI DSN+PGNCLQG SLLHLAC C N VMLELL+QFGADI+MRDFHGRTPLHHCIS+ N AK LLR+GA PSIKD GGLS+LERAME+G+ITDEELFI+LAE
Sbjct: 1 MGAFIKLDDSPMFQKQIFSLEQTADELKNRSQRLYKGCKKFMAALGEACNEDIAFADSLEAFGGGQDDPVSVSIGGPIISKFINAFRELATFKELLRSQVEHVLIDRMMHFMTVDLQDAKESRGRFDKAISAYDQAREKFVSLKKSTRGDIVAELEEDLHNSKSAFEKSRFNLVNALMNVERKKKHEFLESISAIMDAHLRYFKLGYDMLSHMEPFIHQVLTYAQQSKELANIEQDKLAKRIQEFRTQAELDSLRASSNIEPSARVDGIHVVSMSSYKKIEAIMQSAAANGEVQTIKQGYLFKRSSNLRGDWKRRFFVLDSLGTLYYYRNKGTDPMGSSHLYSGSAELNSGVFSRFRTRHNRSSSRNEECLGCHTIELRTSTIKMDADDTDLRLCFRIISPLKTYTLQAENGADRIDWVNKMRGVIASLLNSHFLQQRHPGEKYMENNDSSSGASASCGVPSLDSHSSSEDGMQINRTDFISLSTVLREIPGNDICAECSAPDPDWASLNLGILLCIECSGVHRNLGVHISKVRSLTLDVKVWEPTILDLFHALGNAYSNSIWEGRLLVENERVGESSAMVTSITKPCPKDAISQKEKYIHAKYVEKLLVIRDANVSCMPSCSTRIWQAVKAHNLREVYRLIVTSDTNILNTIFDDVSSVDFYNHIHDAQD---DSHKMKRKEYD-PAACQRIGDSNEPGNCLQGCSLLHLACHCDNPVMLELLLQFGADISMRDFHGRTPLHHCISTGNNQLAKLLLRKGAGPSIKDWGGLSALERAMEIGSITDEELFIMLAE 791
Query: 1 MSAFIKLEDSPMFQKQLFSMEESAEELKDRCQRLYKGCKKFTEALGVACSGDSAFADALEAFGGGHDDPVSVSIGGPVISKFINAFRELATYKELLRSQVEHVLINRLTEFLTVDLHDAKESRRRFDKSIHAYDQAREKFVSLKKNTRDDIVAELEEDLQNSKSAFEKSRFNLVSALTNIEAKKKYEFLESISAIMDVHLRYFKLGFDLLSKIEPYVHQVLTYAQQSKEVANVEQDKLAKRIQEFRTQAELDNLGVPVDVEHSVSADGIHVGGTVSYKNIEAVMRSSATGEVQTIKQGYLLKRSSNLRGDWKRRFFVLNSQGTLYYYRNKGIKSMGSH-HHYAGSADHNGGVFSRFRSRHYRSSSFNEDSLNCRTVDLRTSAIKMDAEDTDLRLCFRIISPVKTYTLQAETEADRMDWTSKITGVIASLLNSDFLQQLRPSAKHIDGNDPFSTR----DIPSLSSHCSLEDEVKANKSDSVSAILRQIPGNDLCAECSAPDPDWASLNLGILLCIECSGVHRNLGVHISKVRSLKLDVKVWEPTILDLFGSLGNAYCNSIWEGLLLLKDREVDKSNTTIPSVRKPCSKDVFHYKEQYIHAKYVEKLLVIRDTSDAK---SRTTSIWEAVKTQNLQEVYRLIVTSDANIINTTFDDVVGVDSYHRVDNTQYSEIDFHKVKKEENNGPAGCQRIKDSNDPGNCLQGGSLLHLACQCGNLVMLELLIQFGADINMRDFHGRTPLHHCISSKNFTFAKFLLRRGARPSIKDGGGLSSLERAMEMGAITDEELFILLAE 786
M+AFI+L+DSPMFQ Q+ S+E+SA+ELKDRCQ+L+KGCKKF ALG A +GD+ FA++LEAFGGG DDPVSVSIGGPV+SKFI+AF ELATYKELLRSQVEHVLI+RLT F+TVDL +AKESRRRFDKSIH YDQARE+FVSLKKNTRDD+VAELEEDL+NSKS FEKSRFNLV++L NIEAKKKYEFLES+SAIMD HLRYFKLG+DLLS++EPY+HQVLTYAQQSKE A VEQDKLAKRIQEFRTQAELD L ++E S DGI V G SYK+IEAV+ S+A GEV TIKQGYLLKRSS+LRGDWKRRFFVLNSQGTL+YYR KG K +GSH HHY SA+ G+F RFRS+H R++S NED L CRTVDLRTS IK+DA+D+DLRLCFRIISPVKTYTLQAE +ADRMDW +KITG I+SLLNS Q R A ++ N S R D+ +L H +LED++ +N+ + VS+ILR +PGNDLCAECSAP+PDWASLNLG+LLCIECSGVHRN GVHISKVRSLKLDVKVWEPTILDLF +LGN YCNSIWEGLL L++ + D SN I S+ KPC KD FH KE++I AKYVEKL+VIRD S A+ +R + IWE+VK+ NL+EVYRLIV SD NI NTTFDDV VD +H V Q +E+ K K+++ P C R+KDSN+PGNCLQG SLLHLAC C NL+M+ELL+QFGA+IN+RDFHGRTPLHHC++S + AKFLL+RGARPSIKDGGGLSSLERAMEMGAITDE+LFILLAE
Sbjct: 1 MAAFIRLDDSPMFQNQVCSIEQSADELKDRCQKLFKGCKKFMAALGEAYNGDTVFAESLEAFGGGTDDPVSVSIGGPVMSKFISAFHELATYKELLRSQVEHVLIDRLTNFMTVDLQEAKESRRRFDKSIHVYDQARERFVSLKKNTRDDVVAELEEDLENSKSEFEKSRFNLVNSLMNIEAKKKYEFLESVSAIMDAHLRYFKLGYDLLSQMEPYIHQVLTYAQQSKEQAKVEQDKLAKRIQEFRTQAELDTLRASSNIEPSTPLDGIRVIGMDSYKSIEAVVPSNANGEVLTIKQGYLLKRSSSLRGDWKRRFFVLNSQGTLFYYRIKGTKPLGSHSHHYTRSAEPTSGMFGRFRSKHNRAASLNEDVLGCRTVDLRTSTIKIDADDSDLRLCFRIISPVKTYTLQAENDADRMDWINKITGAISSLLNSQIFDQPRHVATILENNKS-SARGASCDVQTLGGHQNLEDDINSNRIECVSSILRAVPGNDLCAECSAPEPDWASLNLGVLLCIECSGVHRNFGVHISKVRSLKLDVKVWEPTILDLFRNLGNTYCNSIWEGLLQLENAQTDDSNALITSISKPCPKDAFHLKEKFIQAKYVEKLMVIRDESVAEMPAARASRIWESVKSNNLKEVYRLIVMSDMNITNTTFDDVFPVDLHHHV-GAQETELG-GKTTKKKHVDPGTCDRMKDSNEPGNCLQGCSLLHLACHCENLLMIELLLQFGANINLRDFHGRTPLHHCVASGKNSLAKFLLKRGARPSIKDGGGLSSLERAMEMGAITDEQLFILLAE 791
Query: 1 MSAFIKLEDSPMFQKQLFSMEESAEELKDRCQRLYKGCKKFTEALGVACSGDSAFADALEAFGGGHDDPVSVSIGGPVISKFINAFRELATYKELLRSQVEHVLINRLTEFLTVDLHDAKESRRRFDKSIHAYDQAREKFVSLKKNTRDDIVAELEEDLQNSKSAFEKSRFNLVSALTNIEAKKKYEFLESISAIMDVHLRYFKLGFDLLSKIEPYVHQVLTYAQQSKEVANVEQDKLAKRIQEFRTQAELDNLGVPVDVEHSVSADGIHVGGTVSYKNIEAVMRSSATGEVQTIKQGYLLKRSSNLRGDWKRRFFVLNSQGTLYYYRNKGIKSMGSH-HHYAGSADHNGGVFSRFRSRHYRSSSFNEDSLNCRTVDLRTSAIKMDAEDTDLRLCFRIISPVKTYTLQAETEADRMDWTSKITGVIASLLNSDFLQQLRPSAKHIDGNDPFSTR----DIPSLSSHCSLEDEVKANKSDSVSAILRQIPGNDLCAECSAPDPDWASLNLGILLCIECSGVHRNLGVHISKVRSLKLDVKVWEPTILDLFGSLGNAYCNSIWEGLLLLKDREVDKSNTTIPSVRKPCSKDVFHYKEQYIHAKYVEKLLVIRDTSDAK---SRTTSIWEAVKTQNLQEVYRLIVTSDANIINTTFDDVVGVDSYHRVDNTQYSEIDFHKVKKEENNGPAGCQRIKDSNDPGNCLQGGSLLHLACQCGNLVMLELLIQFGADINMRDFHGRTPLHHCISSKNFTFAKFLLRRGARPSIKDGGGLSSLERAMEMGAITDEELFILLAE 786
M+AFI+L+DSPMFQ Q+ S+E+SA+ELKDRCQ+L+KGCKKF ALG A +GD+ FA++LEAFGGG DDPVSVSIGGPV+SKFI+AF ELAT+KELLRSQVEHVLI+RLT F+TVDL +AKESRRRFDKSIH YDQARE+FVSLKKNTRDD+VAELEEDL+NSKS FEKSRFNLV++L NIEAKKKYEFLES+SAIMD HLRYFKLG+DLLS++EPY+HQVLTYAQQSKE A VEQDKLAKRIQEFRTQAELD L ++E S DGI V G SYK+IEAV+ S+A GEV TIKQGYLLKRSS+LRGDWKRRFFVLNSQGTL+YYR KG K +GSH HHY SA+ G+F RFRS+H R++S NED L CRTVDLRTS IK+DA+D+DLRLCFRIISPVKTYTLQAE +ADRMDW +KITG I+SLLNS Q R A ++ N S R D+ +L H +LED++ +N+ + VS+ILR +PGNDLCAECSAP+PDWASLNLG+LLCIECSGVHRN GVHISKVRSLKLDVKVWEPTILDLF +LGN YCNSIWEGLL L++ + D SN I S+ KPC KD FH KE++I AKYVEKL+VIRD S A+ +R + IWE+VK+ NL+EVYRLIV SD NI NTTFDDV VD +H V Q +E+ K K+++ P C R+KDSN+PGNCLQG SLLHLAC C NL+M+ELL+QFGA+IN+RDFHGRTPLHHC++S + AKFLL+RGARPSIKDGGGLSSLERAMEMGAITDE+LFILLAE
Sbjct: 1 MAAFIRLDDSPMFQNQVCSIEQSADELKDRCQKLFKGCKKFMAALGEAYNGDTVFAESLEAFGGGTDDPVSVSIGGPVMSKFISAFHELATFKELLRSQVEHVLIDRLTNFMTVDLQEAKESRRRFDKSIHVYDQARERFVSLKKNTRDDVVAELEEDLENSKSEFEKSRFNLVNSLMNIEAKKKYEFLESVSAIMDAHLRYFKLGYDLLSQMEPYIHQVLTYAQQSKEQAKVEQDKLAKRIQEFRTQAELDTLRASSNIEPSTPLDGIRVIGMDSYKSIEAVVPSNANGEVLTIKQGYLLKRSSSLRGDWKRRFFVLNSQGTLFYYRIKGTKPLGSHSHHYTRSAEPTSGMFGRFRSKHNRAASLNEDVLGCRTVDLRTSTIKIDADDSDLRLCFRIISPVKTYTLQAENDADRMDWINKITGAISSLLNSQIFDQPRHVATILENNKS-SARGASCDVQTLGGHQNLEDDINSNRIECVSSILRAVPGNDLCAECSAPEPDWASLNLGVLLCIECSGVHRNFGVHISKVRSLKLDVKVWEPTILDLFRNLGNTYCNSIWEGLLQLENAQTDDSNALITSISKPCPKDAFHLKEKFIQAKYVEKLMVIRDESVAEMPAARASRIWESVKSNNLKEVYRLIVMSDMNITNTTFDDVFPVDLHHHV-GAQETELG-GKTTKKKHVDPGTCDRMKDSNEPGNCLQGCSLLHLACHCENLLMIELLLQFGANINLRDFHGRTPLHHCVASGKNSLAKFLLKRGARPSIKDGGGLSSLERAMEMGAITDEQLFILLAE 791
Query: 1 MSAFIKLEDSPMFQKQLFSMEESAEELKDRCQRLYKGCKKFTEALGVACSGDSAFADALEAFGGGHDDPVSVSIGGPVISKFINAFRELATYKELLRSQVEHVLINRLTEFLTVDLHDAKESRRRFDKSIHAYDQAREKFVSLKKNTRDDIVAELEEDLQNSKSAFEKSRFNLVSALTNIEAKKKYEFLESISAIMDVHLRYFKLGFDLLSKIEPYVHQVLTYAQQSKEVANVEQDKLAKRIQEFRTQAELDNLGVPVDVEHSVSADGIHVGGTVSYKNIEAVMRSSATGEVQTIKQGYLLKRSSNLRGDWKRRFFVLNSQGTLYYYRNKGIKSMGSH-HHYAGSADHNGGVFSRFRSRHYRSSSFNEDSLNCRTVDLRTSAIKMDAEDTDLRLCFRIISPVKTYTLQAETEADRMDWTSKITGVIASLLNSDFLQQLRPSAKHI--DGNDPFSTRDIPSLSSHCSLEDEVKANKSDSVSAILRQIPGNDLCAECSAPDPDWASLNLGILLCIECSGVHRNLGVHISKVRSLKLDVKVWEPTILDLFGSLGNAYCNSIWEGLLLLKDREVDKSNTTIPSVRKPCSKDVFHYKEQYIHAKYVEKLLVIRDTSDAKSRT--TSIWEAVKTQNLQEVYRLIVTSDANIINTTFDDVVGVDSYHRV--DNTQYSEIDFHKVKKEENNGPAGCQRIKDSNDPGNCLQGGSLLHLACQCGNLVMLELLIQFGADINMRDFHGRTPLHHCISSKNFTFAKFLLRRGARPSIKDGGGLSSLERAMEMGAITDEELFILLAE 786
M+AFI+L+DSPMFQ Q+ S+E++A+ELKDRCQRLYKGCK + ALG AC GD+ FAD+LEAFGGG DDPVSVSIGGPV+SKFI+A ELATYKELLRSQVEHVLI+RLT F+TVDL +AKESRR FDK+I YDQARE+FVSLKKNTRDDIVAELEEDL+NSKSAFEKSRFNLV+AL N+EAKKKYEFLES+SAIMD HLRYFKLG+DL S++EPY+HQVLTYAQQSKE A VEQD+LAKRIQEFRTQAE++ L ++E S DGI V G SYKNI+AV++SSA GEVQTIKQGYLLKRSS+LRGDWKRRFFVLNSQG LYYYRNKG K GSH H + SA+ + G+F RFRS+H R++S NED L CRTVDLRTS IKMDAED+DLRLCFRIISP+KTYTLQAE +ADRMDW +KI G I SLLNS F + ++ D + S+ D+ +L SH + ED++K+N+ + VS+ILR +PGNDLCAECS+PDPDWASLNLG+LLCIECSGVHRNLGVHISKVRSLKLDVKVWEPTILDLF +LGNAYCNSIWEGLL L++ D +N I S+ KPC +D FH KE+YI AKYVEKL VIRD S A+ T TSIWEAV++ NLQEVYRLIV S NI NTTFDDV VDSYH V ++ +S H K PA C R+K+SN+PGNCLQ SLLHLAC G+L+M+ELL+QFGADIN+RDFHGRTPLHHCISS + AKFLLRRGARPSIKDGGGLSSLERAMEMGAITDEELFILLAE
Sbjct: 1 MAAFIRLDDSPMFQSQICSLEQTADELKDRCQRLYKGCKMYMAALGEACIGDTVFADSLEAFGGGTDDPVSVSIGGPVMSKFISALHELATYKELLRSQVEHVLIDRLTNFMTVDLQEAKESRRCFDKAIRVYDQARERFVSLKKNTRDDIVAELEEDLENSKSAFEKSRFNLVNALMNVEAKKKYEFLESVSAIMDAHLRYFKLGYDLFSQMEPYIHQVLTYAQQSKEQAKVEQDRLAKRIQEFRTQAEMNTLRASSNIEPSAPVDGIRVIGINSYKNIDAVIQSSANGEVQTIKQGYLLKRSSSLRGDWKRRFFVLNSQGALYYYRNKGTKPTGSHSHQFTRSAEPSSGMFGRFRSKHSRTASLNEDVLGCRTVDLRTSIIKMDAEDSDLRLCFRIISPLKTYTLQAENDADRMDWINKIMGAITSLLNSQFFDEPTQVTANLETDKSAGGSSCDVQTLDSHQNSEDDIKSNRIECVSSILRGVPGNDLCAECSSPDPDWASLNLGVLLCIECSGVHRNLGVHISKVRSLKLDVKVWEPTILDLFRNLGNAYCNSIWEGLLQLENARTDDANALITSISKPCPRDAFHRKEKYIQAKYVEKLWVIRDESVAEMPTSATSIWEAVESNNLQEVYRLIVMSCVNITNTTFDDVFHVDSYHHVGLQDSNFS----HDTVKRRYIDPAACDRMKNSNEPGNCLQCCSLLHLACHSGDLLMIELLLQFGADINLRDFHGRTPLHHCISSGKNSLAKFLLRRGARPSIKDGGGLSSLERAMEMGAITDEELFILLAE 789
Query: 1 MSAFIKLEDSPMFQKQLFSMEESAEELKDRCQRLYKGCKKFTEALGVACSGDSAFADALEAFGGGHDDPVSVSIGGPVISKFINAFRELATYKELLRSQVEHVLINRLTEFLTVDLHDAKESRRRFDKSIHAYDQAREKFVSLKKNTRDDIVAELEEDLQNSKSAFEKSRFNLVSALTNIEAKKKYEFLESISAIMDVHLRYFKLGFDLLSKIEPYVHQVLTYAQQSKEVANVEQDKLAKRIQEFRTQAELDNLGVPVDVEHSVSADGIHVGGTVSYKNIEAVMRSSATGEVQTIKQGYLLKRSSNLRGDWKRRFFVLNSQGTLYYYRNKGIKSMGSHHHYAGSADHNGGVFSRFRSRHYRSSSFNEDSLNCRTVDLRTSAIKMDAEDTDLRLCFRIISPVKTYTLQAETEADRMDWTSKITGVIASLLNSDFLQQLRPSAKHIDGNDPFSTRDIPSLSSHCSLEDEVKANKSDSVSAILRQIPGNDLCAECSAPDPDWASLNLGILLCIECSGVHRNLGVHISKVRSLKLDVKVWEPTILDLFGSLGNAYCNSIWEGLLLLKDREVDKSNTTIPSVRKPCSKDVFHYKEQYIHAKYVEKLLVIRDTSDAK-SRTTSIWEAVKTQNLQEVYRLIVTS-DANIINTTFDDVVGVDSYHRVDNTQYSEIDFHKVKKEENNGPAGCQRIKDSNDPGNCLQGGSLLHLACQCGNLVMLELLIQFGADINMRDFHGRTPLHHCISSKNFTFAKFLLRRGARPSIKDGGGLSSLERAMEMGAITDEELFILLAE 786
M+ FI LEDSPMFQKQ+ S+E +A+ELKDRCQ+LYKG KKF LG A G+SAFA LE FGGG DDP+S+SIGGPVISKFINA RELA+YKE L SQVEHVL+ RL F++VDL +AKESR RFDK+ H+YDQ+REKFVSLKKNTR +IVAELEEDL+NSKS FEKSRFNLV++L IEAKKKYEFLESISAIMD HLRYFKLG+DLL+++EP++HQ+LTYAQQSKE + +EQD+LA+RIQEFRTQ+ELD+ + + E S A+G VGG + YKN E +S T + + IKQGYLLKRSS+LR DWKR+FFVL+S G++YYYR G KSMGSHHHY+GS+DHN GVF RFR+RH RS S E SL T+DLRTS IK+DAED DLRLCFRIISP KTYTLQAE ADRMDW +KIT I +LLNS FLQQ +++D ++ S +S ++ + N D VS ILR +PGN+ CAEC+AP+PDWASLNLG+LLCI+CSGVHRNLGVHISKVRSL LDVKVWEPTILDLF +LGN YCNS+WEGLL L D D S + SV KPC +D F KE+YI KY+EK LVI+D S+A S + IWEAV+++N++E+YRLIVT+ D NIINT FDD+ +D+YH +D + + VKK + P CQRIK+SN+P +CLQG SLLH+AC G+ V+LELL+QFGAD+N+RD+HGRTPLHHCISS N FAK LLRRGARPSI+D GGLS LERAMEMGAITDEELF+LLAE
Sbjct: 1 MATFINLEDSPMFQKQVCSLEGTADELKDRCQKLYKGVKKFMGTLGEASKGESAFAACLEEFGGGPDDPISLSIGGPVISKFINALRELASYKEFLCSQVEHVLLERLMNFISVDLQEAKESRHRFDKAAHSYDQSREKFVSLKKNTRGEIVAELEEDLENSKSTFEKSRFNLVNSLMTIEAKKKYEFLESISAIMDAHLRYFKLGYDLLNQLEPFIHQILTYAQQSKEQSKIEQDRLARRIQEFRTQSELDSQQLVANAESS-GANGNRVGGNIPYKNTE----TSLTADKEVIKQGYLLKRSSSLRTDWKRKFFVLDSHGSMYYYRTNGNKSMGSHHHYSGSSDHNTGVFGRFRARHNRSGSLTEGSLGYNTIDLRTSLIKLDAEDMDLRLCFRIISPQKTYTLQAENGADRMDWVNKITKAIGTLLNSHFLQQ--SPVRYLDKDNSSSAPANAVVSGDQIRHNDSRQNIGDDVSTILRGLPGNNACAECNAPEPDWASLNLGVLLCIQCSGVHRNLGVHISKVRSLSLDVKVWEPTILDLFRNLGNVYCNSLWEGLLHLDDDCEDGSALSHASVSKPCPEDSFSVKEKYILGKYLEKALVIKDESEANLSAASRIWEAVQSRNIREIYRLIVTTGDVNIINTKFDDITDIDAYHHIDAAEKA------VKKRHD--PTVCQRIKESNEPRSCLQGCSLLHVACHIGDSVLLELLLQFGADLNIRDYHGRTPLHHCISSGNHKFAKILLRRGARPSIEDDGGLSVLERAMEMGAITDEELFLLLAE 773
Query: 1 MSAFIKLEDSPMFQKQLFSMEESAEELKDRCQRLYKGCKKFTEALGVACSGDSAFADALEAFGGGHDDPVSVSIGGPVISKFINAFRELATYKELLRSQVEHVLINRLTEFLTVDLHDAKESRRRFDKSIHAYDQAREKFVSLKKNTRDDIVAELEEDLQNSKSAFEKSRFNLVSALTNIEAKKKYEFLESISAIMDVHLRYFKLGFDLLSKIEPYVHQVLTYAQQSKEVANVEQDKLAKRIQEFRTQAELDNLGVPVDVEHSVSADGIHVGGTVSYKNIEAVMRSSATGEVQTIKQGYLLKRSSNLRGDWKRRFFVLNSQGTLYYYRNKGIKSMGSHHHYAGSADHNGGVFSRFRSRHYRSSSFNEDSLNCRTVDLRTSAIKMDAEDTDLRLCFRIISPVKTYTLQAETEADRMDWTSKITGVIASLLNSDFLQQLRPSAKHIDGNDPFSTRDIPSLSSHCSLEDEVKANKSDSVSAILRQIPGNDLCAECSAPDPDWASLNLGILLCIECSGVHRNLGVHISKVRSLKLDVKVWEPTILDLFGSLGNAYCNSIWEGLLLLKDREV-----DKSNTTIPSVRKPCSKDVFHYKEQYIHAKYVEKLLVIRDTSDAK-SRTTSIWEAVKTQNLQEVYRLIVTS-DANIINTTFDDVVGVDSYHRVDNTQYSEIDFHKVKKEENNGPAGCQRIKDSNDPGNCLQGGSLLHLACQCGNLVMLELLIQFGADINMRDFHGRTPLHHCISSKNFTFAKFLLRRGARPSIKDGGGLSSLERAMEMGAITDEELFILLAE 786
M+ FI LEDSPMFQKQ+ S+E +A+ELKDRCQ+LYKG KKF LG A G+SAFA LE FGGG DDP+S+SIGGPVISKFINA RELA+YKE L SQVEHVL+ RL F++VDL +AKESR RFDK+ H+YDQ+REKFVSLKKNTR +IVAELEEDL+NSKS FEKSRFNLV++L IEAKKKYEFLESISAIMD HLRYFKLG+DLL+++EP++HQ+LTYAQQSKE + +EQD+LA+RIQEFRTQ+ELD+ + + E S A+G VGG + YKN E +S T + + IKQGYLLKRSS+LR DWKR+FFVL+S G++YYYR G KSMGSHHHY+GS+DHN GVF RFR+RH RS S E SL T+DLRTS IK+DAED DLRLCFRIISP KTYTLQAE ADRMDW +KIT I +LLNS FLQQ +++D ++ S +S ++ + N D VS ILR +PGN+ CAEC+AP+PDWASLNLG+LLCI+CSGVHRNLGVHISKVRSL LDVKVWEPTILDLF +LGN YCNS+WEGLL L D V D S + SV KPC +D F KE+YI KY+EK LVI+D S+A S + IWEAV+++N++E+YRLIVT+ D NIINT FDD+ +D+YH +D + + VKK + P CQRIK+SN+P +CLQG SLLH+AC G+ V+LELL+QFGAD+N+RD+HGRTPLHHCISS N FAK LLRRGARPSI+D GGLS LERAMEMGAITDEELF+LLAE
Sbjct: 1 MATFINLEDSPMFQKQVCSLEGTADELKDRCQKLYKGVKKFMGTLGEASKGESAFAACLEEFGGGPDDPISLSIGGPVISKFINALRELASYKEFLCSQVEHVLLERLMNFISVDLQEAKESRHRFDKAAHSYDQSREKFVSLKKNTRGEIVAELEEDLENSKSTFEKSRFNLVNSLMTIEAKKKYEFLESISAIMDAHLRYFKLGYDLLNQLEPFIHQILTYAQQSKEQSKIEQDRLARRIQEFRTQSELDSQQLVANAESS-GANGNRVGGNIPYKNTE----TSLTADKEVIKQGYLLKRSSSLRTDWKRKFFVLDSHGSMYYYRTNGNKSMGSHHHYSGSSDHNTGVFGRFRARHNRSGSLTEGSLGYNTIDLRTSLIKLDAEDMDLRLCFRIISPQKTYTLQAENGADRMDWVNKITKAIGTLLNSHFLQQ--SPVRYLDKDNSSSAPANAVVSGDQIRHNDSRQNIGDDVSTILRGLPGNNACAECNAPEPDWASLNLGVLLCIQCSGVHRNLGVHISKVRSLSLDVKVWEPTILDLFRNLGNVYCNSLWEGLLHLDDDCVAFCSEDGSALSHASVSKPCPEDSFSVKEKYILGKYLEKALVIKDESEANLSAASRIWEAVQSRNIREIYRLIVTTGDVNIINTKFDDITDIDAYHHIDAAEKA------VKKRHD--PTVCQRIKESNEPRSCLQGCSLLHVACHIGDSVLLELLLQFGADLNIRDYHGRTPLHHCISSGNHKFAKILLRRGARPSIEDDGGLSVLERAMEMGAITDEELFLLLAE 778
Query: 4 FIKLEDSPMFQKQLFSMEESAEELKDRCQRLYKGCKKFTEALGVACSGDSAFADALEAFGGGHDDPVSVSIGGPVISKFINAFRELATYKELLRSQVEHVLINRLTEFLTVDLHDAKESRRRFDKSIHAYDQAREKFVSLKKNTRDDIVAELEEDLQNSKSAFEKSRFNLVSALTNIEAKKKYEFLESISAIMDVHLRYFKLGFDLLSKIEPYVHQVLTYAQQSKEVANVEQDKLAKRIQEFRTQAELDNLGVPVDVEHSVSADGIHVGGTVSYKNIEAVMRSSATGEVQTIKQGYLLKRSSNLRGDWKRRFFVLNSQGTLYYYRNKGIKSMGSHHHYAG---SADHNGGVFSRFRS--RHYRSSSFNEDSLNCRTVDLRTSAIKMDAEDTDLRLCFRIISPVKTYTLQAETEADRMDWTSKITGVIASLLNSDFLQQLRPSAKHIDGN---------DPFSTRDIPSLSSHC--------------SLEDEVKANKSDSVSAILRQIPGNDLCAECSAPDPDWASLNLGILLCIECSGVHRNLGVHISKVRSLKLDVKVWEPTILDLFGSLGNAYCNSIWEGLLLLKD--------REVDKSNTTIPSVRKPCSKDVFHYKEQYIHAKYVEKLLV--IRDTSDAKSRTTSIWEAVKTQNLQEVYRLIVTSDANIINTTFDDVVGVDSYHR----VDNTQYSEIDFHKVKKEENNGPAGCQRIKDSNDPGNCLQGGSLLHLACQCGNLVMLELLIQFGADINMRDFHGRTPLHHCISSKNFTFAKFLLRRGARPSIKDGGGLSSLERAMEMGAITDEELFILLAES 787
F KL+DSPMF+KQL SMEESAE L++R + YKGC+K+TE LG A GD AFA ALE FGGGH+DP+SV+ GGPV++KF A RE+ TYKE+LRSQVEH+L +RL +F +DLH+ KE+R+RFDK+ YDQAREKF+SL+K T+ D+ A LE++L S+S FE++RFNLV+AL+N+EAKK++EFLE++S MD HLRYFK G++LL ++EPY++QVLTYAQQS+E +N EQ L +++QE++ Q + ++ S + DGI G S+K I+AVM+S+A G+VQTI+QGYL KRSSNLRGDWKRRFFVL+S+G LYYYR + K GS +G S++ G+ SR+ S H +E S+ TV+L TS IK+DA+ +DLR CFRIISP K YTLQAE+ D+MDW KITGVIASLL+S +Q P + G+ S D P+ S + + K + LR++ GND CA+C AP+PDWASLNLG+L+CIECSGVHRNLGVHISKVRSL LDVKVWEP+++ LF +LGN + N++WE LL + DKS + KP D+ KE+YI AKY EKL V RD+ +S +W+AV + + VYRLIV DA+ +N +D V E +++ E + I G+ SLLH AC+ +L M+ELL+Q+GA++N D G+TPLH C+ T A+ LL RGA P + G ++L+ A E TD E+ LL+++
Sbjct: 3 FTKLDDSPMFRKQLQSMEESAEILRERSLKFYKGCRKYTEGLGEAYDGDIAFASALETFGGGHNDPISVAFGGPVMTKFTIALREIGTYKEVLRSQVEHILNDRLLQFANMDLHEVKEARKRFDKASLTYDQAREKFLSLRKGTKSDVAAALEQELHTSRSMFEQARFNLVTALSNVEAKKRFEFLEAVSGTMDAHLRYFKQGYELLHQMEPYINQVLTYAQQSRERSNYEQAALNEKMQEYKRQVDRESRWGSNGSNGSPNGDGIQAIGRSSHKMIDAVMQSAARGKVQTIRQGYLSKRSSNLRGDWKRRFFVLDSRGMLYYYRKQCSKPSGSGSQLSGQRNSSELGSGLLSRWLSSNNHGHGGVHDEKSVARHTVNLLTSTIKVDADQSDLRFCFRIISPTKNYTLQAESALDQMDWIEKITGVIASLLSSQVPEQRLPGSPMGSGHHRSASESSSYESSEYDHPTTEEFVCERSFLGYNERPSRSFQPQRSIRKGEKPIDALRKVCGNDKCADCGAPEPDWASLNLGVLVCIECSGVHRNLGVHISKVRSLTLDVKVWEPSVISLFQALGNTFANTVWEELLHSRSAIHFDPGLTVSDKSRVMVTG--KPSYADMISIKEKYIQAKYAEKLFVRRSRDSDFPQSAAQQMWDAVSGNDKKAVYRLIVNGDAD-VNYVYDQTSSSSLTLSRVILVPERPKREDVLLRLRNELLDRTGSSSNISPEGSGGS-----SLLHCACEKADLGMVELLLQYGANVNASDSSGQTPLHCCLLRGKVTIARLLLTRGADPEAMNREGKTALDIAAESN-FTDPEVLALLSDT 819
Query: 4 FIKLEDSPMFQKQLFSMEESAEELKDRCQRLYKGCKKFTEALGVACSGDSAFADALEAFGGGHDDPVSVSIGGPVISKFINAFRELATYKELLRSQVEHVLINRLTEFLTVDLHDAKESRRRFDKSIHAYDQAREKFVSLKKNTRDDIVAELEEDLQNSKSAFEKSRFNLVSALTNIEAKKKYEFLESISAIMDVHLRYFKLGFDLLSKIEPYVHQVLTYAQQSKEVANVEQDKLAKRIQEFRTQAELDNLGVPVDVEHSVSADGIHVGGTVSYKNIEAVMRSSATGEVQTIKQGYLLKRSSNLRGDWKRRFFVLNSQGTLYYYRNKGIKSMG----SHHHYAGSADHNGGVFSRFRSRHYRSSSFNEDSLNCRTVDLRTSAIKMDAEDTDLRLCFRIISPVKTYTLQAETEADRMDWTSKITGVIASLLNSDFLQQLRPSAKHIDGNDPFSTRDIPSL----------SSHCSLEDEVKANKSDSVSAILRQ---------------IPGNDLCAECSAPDPDWASLNLGILLCIECSGVHRNLGVHISKVRSLKLDVKVWEPTILDLFGSLGNAYCNSIWEGLL-LLKDREVDKSNTTIPS--------VRKPCSKDVFHYKEQYIHAKYVEKLLVIR--DTSDAKSRTTSIWEAVKTQNLQEVYRLIVTS--DANIINTTFDDVVGVDSYHRVDNTQYSEIDFHKVKKEENNGPAGCQ----------RIKDSNDPGNCLQGGSLLHLACQCGNLVMLELLIQFGADINMRDFHGRTPLHHCISSKNFTFAKFLLRRGARPSIKDGGGLSSLERAMEMGAITDEELFILLAES 787
F KL+DSPMF++Q+ SMEESAE L+ RC R YKGC+K+TE LG D F +ALE+FGGGH+DPV V+ GGPV++KF A RE+ TYKE+LRSQVEH+L +RL +F+ D+H+ KE+R+RFDK+ YDQAREK++SL+K+TR D+ A +EEDL ++++ FE++RF+LVSAL+N E+KK++EFLE++S MD HLR+FK G++LL ++EP+++QVL YA QS+E AN E L +R+QE++ Q + + V S + DG+ S K IEAVM+S+A G+VQTI+QGYL KRSSNLRGDWKRRFF+L+S+G LYYYR S G S H +++++ G+ SR+ S HY +E + TV+L TS IK+DA+ TDLR CFRIISP K YTLQAE D+MDW KITGVIASLL+ ++ +DG D FS D SL S ++E + S L+Q + GN+ CA+C AP+PDWASLNLG+L+CIECSG+HRNLGVHISKVRSL LDVKVWEP++L LF SLGN Y NS+WE LL ++ P VRKP D KE +IHAKY E++ V + D+ ++ IWE V+ + + VYR IV S D N + V + + + E F +++E PAG R + SND C SLLHLAC ++ M+ELL+Q+GA IN D GRTPLHHCI S+ + A+ LL RG P+ D ++ A + + D EL LL +S
Sbjct: 3 FAKLDDSPMFRQQMQSMEESAELLRLRCLRFYKGCRKYTEGLGEGYDADIGFVNALESFGGGHNDPVCVAFGGPVMTKFTIALREIGTYKEVLRSQVEHMLSDRLLQFVNGDVHEVKEARKRFDKATITYDQAREKYLSLRKSTRLDVAATIEEDLHSARTTFEQARFHLVSALSNAESKKRFEFLEAVSGTMDAHLRFFKQGYELLHQMEPFINQVLAYAHQSRECANYEMASLNERMQEYQRQVDRETRNSCV----SPTGDGMRHNSRNSQKVIEAVMQSAAKGKVQTIRQGYLSKRSSNLRGDWKRRFFILDSRGMLYYYRKPWNWSSGNGSRSVVHRNMASENSPGLLSRWLSSHYHGGVHDEKPVARHTVNLLTSTIKVDADQTDLRFCFRIISPTKVYTLQAENAQDQMDWIEKITGVIASLLSFQTPERAIMRLSTVDGGDTFSASDSGSLADPYDIEQAESGESTVEHPMTGGNRSRFSGCLQQHDMVKTEKPIDVLTRVLGNERCADCGAPEPDWASLNLGVLICIECSGIHRNLGVHISKVRSLTLDVKVWEPSVLTLFQSLGNVYVNSVWEELLNSESRTSSASRSSGTPKSDRPRKLLVRKPGFNDPISVKELFIHAKYSERIFVRKAIDSQHFQAVFQEIWENVRANDKKSVYRHIVCSEADVNALRGQASYTVSLPLSKMMQMEETLEAKFKSIEEEFQENPAGYSNSRGDGESMVREETSND---C----SLLHLACLSADIGMVELLLQYGAKINATDSKGRTPLHHCIISRRYAIARLLLMRGGDPNAVDKDSNIPVKYASQTD-LNDSELIALLTDS 826
Query: 463 SLEDEVKANKSDSVSAILRQIPGNDLCAECSAPDPDWASLNLGILLCIECSGVHRNLGVHISKVRSLKLDVKVWEPTILDLFGSLGNAYCNSIWEGLL 560
S+ E+ A S + A+L+ P N CA+C + P WAS+NLGI +C++CSG+HR+LGVHIS+VRS+ LD W P + S GNA N WE L
Sbjct: 6 SVSKELNAKHSKILEALLKH-PDNRECADCRSKAPRWASVNLGIFICMQCSGIHRSLGVHISQVRSITLD--TWLPDQVAFMKSTGNAKGNEYWESEL 100
Query: 463 SLEDEVKANKSDSVSAILRQIPGNDLCAECSAPDPDWASLNLGILLCIECSGVHRNLGVHISKVRSLKLDVKVWEPTILDLFGSLGNAYCNSIWEGLL 560
S+ E+ A S + A+L+ P N CA+C + P WAS+NLGI +C++CSG+HR+LGVHIS+VRS+ LD W P + S GNA N WE L
Sbjct: 6 SVSKELNAKHSKILEALLKH-PDNRECADCRSKAPRWASVNLGIFICMQCSGIHRSLGVHISQVRSITLD--TWLPDQVAFMKSTGNAKGNEYWESEL 100
Query: 463 SLEDEVKANKSDSVSAILRQIPGNDLCAECSAPDPDWASLNLGILLCIECSGVHRNLGVHISKVRSLKLDVKVWEPTILDLFGSLGNAYCNSIWEGLL 560
S+ E+ A S + A+L+ P N CA+C + P WAS+NLGI +C++CSG+HR+LGVHIS+VRS+ LD W P + S GNA N WE L
Sbjct: 6 SVSKELNAKHSKILEALLKH-PDNRECADCRSKAPRWASVNLGIFICMQCSGIHRSLGVHISQVRSITLD--TWLPDQVAFMKSTGNAKGNEYWESEL 100
Query: 1 MSAFIKLEDSPMFQKQLFSMEESAEELKDRCQRLYKGCKKFTEALGVACSGDSAFADALEAFGGGHDDPVSVSIGGPVISKFINAFRELATYKELLRSQVEHVLINRLTEFLTVDLHDAKESRRRFDKSIHAYDQAREKFVSLKKNTRDDIVAELEEDLQNSKSAFEKSRFNLVSALTNIEAKKKYEFLESISAIMDVHLRYFKLGFDLLSKIEPYVHQVLTYAQQSKEVANVEQDKLAKRIQEFRTQAELDNLGVPVDVEHSVSADGIHVGGTVSYKNIEAVMRSSATGEVQTIKQGYLLKRSSNLRGDWKRRFFVLNSQGTLYYYRNKGIKSMGSHHHYAGSADHNGGVFSRFRSRHYRSSSFNEDSLNCRTVDLRTSAIKMDAEDTDLRLCFRIISPVKTYTLQAETEADRMDWTSKITGVIASLLNSDFLQQLRPSAKHIDGNDPFSTRDIPSLSSHCSLEDEVKANKSDSVSAILRQIPGNDLCAECSAPDPDWASLNLGILLCIECSGVHRNLGVHISKVRSLKLDVKVWEPTILDLFGSLGNAYCNSIWEGLLLLKDREVDKSNTTIPSVRKPCSKDVFHYKEQYIHAKYVEKLLVIRDTSDAK-SRTTSIWEAVKTQNLQEVYRLIVTS-DANIINTTFDDVVGVDSYHRVDNTQYSEIDFHKVKKEENNGPAGCQRIKDSNDPGNCLQGGSLLHLACQCGNLVMLELLIQFGADINMRDFHGRTPLHHCISSKNFTFAKFLLRRGARPSIKDGGGLSSLERAMEMGAITDEELFILLAE 786
M+ FI LEDSPMFQKQ+ S+E +A+ELKDRCQ+LYKG KKF LG A G+SAFA LE FGGG DDP+S+SIGGPVISKFINA RELA+YKE L SQVEHVL+ RL F++VDL +AKESR RFDK+ H+YDQ+REKFVSLKKNTR +IVAELEEDL+NSKS FEKSRFNLV++L IEAKKKYEFLESISAIMD HLRYFKLG+DLL+++EP++HQ+LTYAQQSKE + +EQD+LA+RIQEFRTQ+ELD+ + + E S A+G VGG + YKN E +S T + + IKQGYLLKRSS+LR DWKR+FFVL+S G++YYYR G KSMGSHHHY+GS+DHN GVF RFR+RH RS S E SL T+DLRTS IK+DAED DLRLCFRIISP KTYTLQAE ADRMDW +KIT I +LLNS FLQQ +++D ++ S +S ++ + N D VS ILR +PGN+ CAEC+AP+PDWASLNLG+LLCI+CSGVHRNLGVHISKVRSL LDVKVWEPTILDLF +LGN YCNS+WEGLL L D D S + SV KPC +D F KE+YI KY+EK LVI+D S+A S + IWEAV+++N++E+YRLIVT+ D NIINT FDD+ +D+YH +D + + VKK + P CQRIK+SN+P +CLQG SLLH+AC G+ V+LELL+QFGAD+N+RD+HGRTPLHHCISS N FAK LLRRGARPSI+D GGLS LERAMEMGAITDEELF+LLAE
Sbjct: 1 MATFINLEDSPMFQKQVCSLEGTADELKDRCQKLYKGVKKFMGTLGEASKGESAFAACLEEFGGGPDDPISLSIGGPVISKFINALRELASYKEFLCSQVEHVLLERLMNFISVDLQEAKESRHRFDKAAHSYDQSREKFVSLKKNTRGEIVAELEEDLENSKSTFEKSRFNLVNSLMTIEAKKKYEFLESISAIMDAHLRYFKLGYDLLNQLEPFIHQILTYAQQSKEQSKIEQDRLARRIQEFRTQSELDSQQLVANAESS-GANGNRVGGNIPYKNTE----TSLTADKEVIKQGYLLKRSSSLRTDWKRKFFVLDSHGSMYYYRTNGNKSMGSHHHYSGSSDHNTGVFGRFRARHNRSGSLTEGSLGYNTIDLRTSLIKLDAEDMDLRLCFRIISPQKTYTLQAENGADRMDWVNKITKAIGTLLNSHFLQQ--SPVRYLDKDNSSSAPANAVVSGDQIRHNDSRQNIGDDVSTILRGLPGNNACAECNAPEPDWASLNLGVLLCIQCSGVHRNLGVHISKVRSLSLDVKVWEPTILDLFRNLGNVYCNSLWEGLLHLDDDCEDGSALSHASVSKPCPEDSFSVKEKYILGKYLEKALVIKDESEANLSAASRIWEAVQSRNIREIYRLIVTTGDVNIINTKFDDITDIDAYHHIDAAEKA------VKKRHD--PTVCQRIKESNEPRSCLQGCSLLHVACHIGDSVLLELLLQFGADLNIRDYHGRTPLHHCISSGNHKFAKILLRRGARPSIEDDGGLSVLERAMEMGAITDEELFLLLAE 773
Query: 4 FIKLEDSPMFQKQLFSMEESAEELKDRCQRLYKGCKKFTEALGVACSGDSAFADALEAFGGGHDDPVSVSIGGPVISKFINAFRELATYKELLRSQVEHVLINRLTEFLTVDLHDAKESRRRFDKSIHAYDQAREKFVSLKKNTRDDIVAELEEDLQNSKSAFEKSRFNLVSALTNIEAKKKYEFLESISAIMDVHLRYFKLGFDLLSKIEPYVHQVLTYAQQSKEVANVEQDKLAKRIQEFRTQAELDNLGVPVDVEHSVSADGIHVGGTVSYKNIEAVMRSSATGEVQTIKQGYLLKRSSNLRGDWKRRFFVLNSQGTLYYYRNKGIKSMGSHHHYAG---SADHNGGVFSRFRS--RHYRSSSFNEDSLNCRTVDLRTSAIKMDAEDTDLRLCFRIISPVKTYTLQAETEADRMDWTSKITGVIASLLNSDFLQQLRPSAKHIDGN---------DPFSTRDIPSLSSHC--------------SLEDEVKANKSDSVSAILRQIPGNDLCAECSAPDPDWASLNLGILLCIECSGVHRNLGVHISKVRSLKLDVKVWEPTILDLFGSLGNAYCNSIWEGLLLLKD--------REVDKSNTTIPSVRKPCSKDVFHYKEQYIHAKYVEKLLV--IRDTSDAKSRTTSIWEAVKTQNLQEVYRLIVTSDANIINTTFDDVVGVDSYHR----VDNTQYSEIDFHKVKKEENNGPAGCQRIKDSNDPGNCLQGGSLLHLACQCGNLVMLELLIQFGADINMRDFHGRTPLHHCISSKNFTFAKFLLRRGARPSIKDGGGLSSLERAMEMGAITDEELFILLAES 787
F KL+DSPMF+KQL SMEESAE L++R + YKGC+K+TE LG A GD AFA ALE FGGGH+DP+SV+ GGPV++KF A RE+ TYKE+LRSQVEH+L +RL +F +DLH+ KE+R+RFDK+ YDQAREKF+SL+K T+ D+ A LE++L S+S FE++RFNLV+AL+N+EAKK++EFLE++S MD HLRYFK G++LL ++EPY++QVLTYAQQS+E +N EQ L +++QE++ Q + ++ S + DGI G S+K I+AVM+S+A G+VQTI+QGYL KRSSNLRGDWKRRFFVL+S+G LYYYR + K GS +G S++ G+ SR+ S H +E S+ TV+L TS IK+DA+ +DLR CFRIISP K YTLQAE+ D+MDW KITGVIASLL+S +Q P + G+ S D P+ S + + K + LR++ GND CA+C AP+PDWASLNLG+L+CIECSGVHRNLGVHISKVRSL LDVKVWEP+++ LF +LGN + N++WE LL + DKS + KP D+ KE+YI AKY EKL V RD+ +S +W+AV + + VYRLIV DA+ +N +D V E +++ E + I G+ SLLH AC+ +L M+ELL+Q+GA++N D G+TPLH C+ T A+ LL RGA P + G ++L+ A E TD E+ LL+++
Sbjct: 3 FTKLDDSPMFRKQLQSMEESAEILRERSLKFYKGCRKYTEGLGEAYDGDIAFASALETFGGGHNDPISVAFGGPVMTKFTIALREIGTYKEVLRSQVEHILNDRLLQFANMDLHEVKEARKRFDKASLTYDQAREKFLSLRKGTKSDVAAALEQELHTSRSMFEQARFNLVTALSNVEAKKRFEFLEAVSGTMDAHLRYFKQGYELLHQMEPYINQVLTYAQQSRERSNYEQAALNEKMQEYKRQVDRESRWGSNGSNGSPNGDGIQAIGRSSHKMIDAVMQSAARGKVQTIRQGYLSKRSSNLRGDWKRRFFVLDSRGMLYYYRKQCSKPSGSGSQLSGQRNSSELGSGLLSRWLSSNNHGHGGVHDEKSVARHTVNLLTSTIKVDADQSDLRFCFRIISPTKNYTLQAESALDQMDWIEKITGVIASLLSSQVPEQRLPGSPMGSGHHRSASESSSYESSEYDHPTTEEFVCERSFLGYNERPSRSFQPQRSIRKGEKPIDALRKVCGNDKCADCGAPEPDWASLNLGVLVCIECSGVHRNLGVHISKVRSLTLDVKVWEPSVISLFQALGNTFANTVWEELLHSRSAIHFDPGLTVSDKSRVMVTG--KPSYADMISIKEKYIQAKYAEKLFVRRSRDSDFPQSAAQQMWDAVSGNDKKAVYRLIVNGDAD-VNYVYDQTSSSSLTLSRVILVPERPKREDVLLRLRNELLDRTGSSSNISPEGSGGS-----SLLHCACEKADLGMVELLLQYGANVNASDSSGQTPLHCCLLRGKVTIARLLLTRGADPEAMNREGKTALDIAAESN-FTDPEVLALLSDT 819
Query: 4 FIKLEDSPMFQKQLFSMEESAEELKDRCQRLYKGCKKFTEALGVACSGDSAFADALEAFGGGHDDPVSVSIGGPVISKFINAFRELATYKELLRSQVEHVLINRLTEFLTVDLHDAKESRRRFDKSIHAYDQAREKFVSLKKNTRDDIVAELEEDLQNSKSAFEKSRFNLVSALTNIEAKKKYEFLESISAIMDVHLRYFKLGFDLLSKIEPYVHQVLTYAQQSKEVANVEQDKLAKRIQEFRTQAELDNLGVPVDVEHSVSADGIHVGGTVSYKNIEAVMRSSATGEVQTIKQGYLLKRSSNLRGDWKRRFFVLNSQGTLYYYRNKGIKSMG----SHHHYAGSADHNGGVFSRFRSRHYRSSSFNEDSLNCRTVDLRTSAIKMDAEDTDLRLCFRIISPVKTYTLQAETEADRMDWTSKITGVIASLLNSDFLQQLRPSAKHIDGNDPFSTRDIPSL----------SSHCSLEDEVKANKSDSVSAILRQ---------------IPGNDLCAECSAPDPDWASLNLGILLCIECSGVHRNLGVHISKVRSLKLDVKVWEPTILDLFGSLGNAYCNSIWEGLL-LLKDREVDKSNTTIPS--------VRKPCSKDVFHYKEQYIHAKYVEKLLVIR--DTSDAKSRTTSIWEAVKTQNLQEVYRLIVTS--DANIINTTFDDVVGVDSYHRVDNTQYSEIDFHKVKKEENNGPAGCQ----------RIKDSNDPGNCLQGGSLLHLACQCGNLVMLELLIQFGADINMRDFHGRTPLHHCISSKNFTFAKFLLRRGARPSIKDGGGLSSLERAMEMGAITDEELFILLAES 787
F KL+DSPMF++Q+ SMEESAE L+ RC R YKGC+K+TE LG D F +ALE+FGGGH+DPV V+ GGPV++KF A RE+ TYKE+LRSQVEH+L +RL +F+ D+H+ KE+R+RFDK+ YDQAREK++SL+K+TR D+ A +EEDL ++++ FE++RF+LVSAL+N E+KK++EFLE++S MD HLR+FK G++LL ++EP+++QVL YA QS+E AN E L +R+QE++ Q + + V S + DG+ S K IEAVM+S+A G+VQTI+QGYL KRSSNLRGDWKRRFF+L+S+G LYYYR S G S H +++++ G+ SR+ S HY +E + TV+L TS IK+DA+ TDLR CFRIISP K YTLQAE D+MDW KITGVIASLL+ ++ +DG D FS D SL S ++E + S L+Q + GN+ CA+C AP+PDWASLNLG+L+CIECSG+HRNLGVHISKVRSL LDVKVWEP++L LF SLGN Y NS+WE LL ++ P VRKP D KE +IHAKY E++ V + D+ ++ IWE V+ + + VYR IV S D N + V + + + E F +++E PAG R + SND C SLLHLAC ++ M+ELL+Q+GA IN D GRTPLHHCI S+ + A+ LL RG P+ D ++ A + + D EL LL +S
Sbjct: 3 FAKLDDSPMFRQQMQSMEESAELLRLRCLRFYKGCRKYTEGLGEGYDADIGFVNALESFGGGHNDPVCVAFGGPVMTKFTIALREIGTYKEVLRSQVEHMLSDRLLQFVNGDVHEVKEARKRFDKATITYDQAREKYLSLRKSTRLDVAATIEEDLHSARTTFEQARFHLVSALSNAESKKRFEFLEAVSGTMDAHLRFFKQGYELLHQMEPFINQVLAYAHQSRECANYEMASLNERMQEYQRQVDRETRNSCV----SPTGDGMRHNSRNSQKVIEAVMQSAAKGKVQTIRQGYLSKRSSNLRGDWKRRFFILDSRGMLYYYRKPWNWSSGNGSRSVVHRNMASENSPGLLSRWLSSHYHGGVHDEKPVARHTVNLLTSTIKVDADQTDLRFCFRIISPTKVYTLQAENAQDQMDWIEKITGVIASLLSFQTPERAIMRLSTVDGGDTFSASDSGSLADPYDIEQAESGESTVEHPMTGGNRSRFSGCLQQHDMVKTEKPIDVLTRVLGNERCADCGAPEPDWASLNLGVLICIECSGIHRNLGVHISKVRSLTLDVKVWEPSVLTLFQSLGNVYVNSVWEELLNSESRTSSASRSSGTPKSDRPRKLLVRKPGFNDPISVKELFIHAKYSERIFVRKAIDSQHFQAVFQEIWENVRANDKKSVYRHIVCSEADVNALRGQASYTVSLPLSKMMQMEETLEAKFKSIEEEFQENPAGYSNSRGDGESMVREETSND---C----SLLHLACLSADIGMVELLLQYGAKINATDSKGRTPLHHCIISRRYAIARLLLMRGGDPNAVDKDSNIPVKYASQTD-LNDSELIALLTDS 826
BLAST of hap2-g23221.t1 vs. ExPASy Swiss-Prot (2024) Match: sp|Q5FVC7|ACAP2_RAT (Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2 OS=Rattus norvegicus OX=10116 GN=Acap2 PE=1 SV=1)
Query: 7 LEDSPMFQKQLFSMEESAEELKDRCQRLYKGCKKFTEALGVACSGDSAFADALEAFGGGHDDPVSVSIGGPVISKFINAFRELATYKELLRSQVEHVLINRLTEFLTVDLHDAKESRRRFDKSIHAYDQAREKFVSLKKNTRDDIVAELEEDLQNSKSAFEKSRFNLVSALTNIEAKKKYEFLESISAIMDVHLRYFKLGFDLLSKIEPYVHQVLTYAQQSKEVANVEQDKLAKRIQEFRTQAELDNLGVPVDVEHSV-SADGIHVGGTVSYKNIEAVMRSSATGEVQTIKQGYLLKRSSNLRGDWKRRFFVLNSQGTLYYYRNKGIKSMGSHHHYAGSADHNGGVFSRFRSRHYRSSSFNEDSLNCRTVDLRTSAIKMDAEDTDLRLCFRIISPVKTYTLQAETEADRMDWTSKITGVIASLLNSDFLQQLRPSAKHIDGNDPFSTRDIPSLSSHCSLEDEVKANKSDSVSAILRQIPGNDLCAECSAPDPDWASLNLGILLCIECSGVHRNLGVHISKVRSLKLDVKVWEPTILDLFGSLGNAYCNSIWEGLLLLKDREVDKSNTTIPSVRKPCSKDVFHYKEQYIHAKYVEKLLVIRDT---SDAKSRTTSIWEAVKTQNLQ----EVYRLIVTSDANIINTTFD-----------------------DVVGVDSYHRVDNTQYSEIDFHKVKKEENNGPAGCQRIKDSNDPGNCLQGGSLLHLACQCGNLVMLELLIQFGADINMRDFHGRTPLHHCISSKNFTFAKFLLRRGARPSIKDGGGLSSLERAME 771
L+DSP F+ L +E EL+ + +L K C + C+ + F + + + V ++KF ++ +E+ + +L Q + + +L F+ DL K+++++F+K + A K +++N + + V E L ++ F + V + +++K++ E L+S+ + M HL +F G+DL S++ PY+ + AQ + V + ++K Q+ T + D +E++V +A+GI + +GYL KR+SN W RR+F + + +Y + K DS DLR +K ED + R CF ++SP K+ LQA++E R W + IA+ R + D S+ SL S E + K K +S ++ IPGN C +C DP WAS+NLGI LCIECSG+HR+LGVH SKVRSL LD WEP +L L LGN N ++E L +K P +P + KE YI AKYVE+ V + + S ++ I ++ + Q L V+ + ++D+ I + D V +DS H Q + K + A + +N N Q L+ A G+LV E L+Q GA++N RD GR PLHH + L+RGA D G L A+E
Sbjct: 11 LKDSPRFRAALEEVEGDVAELELKLDKLVKLCIAMIDTGKAFCAANKQFMNGIRDLAQYSSNDAVVETS---LTKFSDSLQEMINFHTILFDQTQRSIKAQLQNFVKEDLRKFKDAKKQFEKVSEEKENALVKNAQVQRNKQHE-VEEAANILTATRKCFRHIALDYVLQINVLQSKRRSEILKSMLSFMYAHLAFFHQGYDLFSELGPYMKDL--GAQLDRLVVDAAKEKREME-QKHSTIQQKDFSSDDSKLEYNVDAANGI-------------------------VMEGYLFKRASNAFKTWNRRWFSIQNNQLVYQKKFK-------------------------------------DSPTVVVEDLRLCTVK-HCEDIERRFCFEVVSPTKSCMLQADSEKLRQAWIKAVQTSIATAY--------REKGDESEKLDKKSSPSTGSLDS--GSESKEKLLKGESALQRVQCIPGNTSCCDCGLADPRWASINLGITLCIECSGIHRSLGVHFSKVRSLTLD--TWEPELLKLMCELGNDVINRVYEAKL-------EKMGVKKP---QPGQR---QEKEAYIRAKYVERKFVDKYSTLLSPSEQEKRIISKSCEDQRLSHTRVSVHTPVKSNDSGIQQCSDDGRESLPSTVSANSLYEPEGERQESSVFLDSKHLNPGLQLYRASYEKNLPKMAEALAHGADVNWANSDEN--QATPLIQ-AVLGGSLVTCEFLLQNGANVNQRDVQGRGPLHHATVLGHTGQVCLFLKRGANQHATDEEGKDPLSIAVE 708
BLAST of hap2-g23221.t1 vs. ExPASy Swiss-Prot (2024) Match: sp|Q6ZQK5|ACAP2_MOUSE (Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2 OS=Mus musculus OX=10090 GN=Acap2 PE=1 SV=2)
Query: 7 LEDSPMFQKQLFSMEESAEELKDRCQRLYKGCKKFTEALGVACSGDSAFADALEAFGGGHDDPVSVSIGGPVISKFINAFRELATYKELLRSQVEHVLINRLTEFLTVDLHDAKESRRRFDKSIHAYDQAREKFVSLKKNTRDDIVAELEEDLQNSKSAFEKSRFNLVSALTNIEAKKKYEFLESISAIMDVHLRYFKLGFDLLSKIEPYVHQVLTYAQQSKEVANVEQDKLAKRIQEFRTQAELDNLGVPVDVEHSV-SADGIHVGGTVSYKNIEAVMRSSATGEVQTIKQGYLLKRSSNLRGDWKRRFFVLNSQGTLYYYRNKGIKSMGSHHHYAGSADHNGGVFSRFRSRHYRSSSFNEDSLNCRTVDLRTSAIKMDAEDTDLRLCFRIISPVKTYTLQAETEADRMDWTSKITGVIASLLNSDFLQQLRPSAKHIDGNDPFSTRDIPSLSSHCSLEDEVKANKSDSVSAILRQIPGNDLCAECSAPDPDWASLNLGILLCIECSGVHRNLGVHISKVRSLKLDVKVWEPTILDLFGSLGNAYCNSIWEGLLLLKDREVDKSNTTIPSVRKPCSKDVFHYKEQYIHAKYVEKLLVIRDT---SDAKSRTTSIWEAVKTQNLQE----VYRLIVTSDANIINTTFD-----------------------DVVGVDSYHRVDNTQYSEIDFHKVKKEENNGPAGCQRIKDSNDPGNCLQGGSLLHLACQCGNLVMLELLIQFGADINMRDFHGRTPLHHCISSKNFTFAKFLLRRGARPSIKDGGGLSSLERAME 771
L+DSP F+ L +E EL+ + +L K C + C + F + + + V ++KF ++ +E+ + +L Q + + +L F+ DL K+++++F+K + A K +++N + + V E L ++ F + V + +++K++ E L+S+ + M HL +F G+DL S++ PY+ + AQ + V + ++K Q+ T + D +E++V +A+GI + +GYL KR+SN W RR+F + + +Y + K DS DLR +K ED + R CF ++SP K+ LQA++E R W + IA+ R + D S+ SL S E + K K +S ++ IPGN C +C DP WAS+NLGI LCIECSG+HR+LGVH SKVRSL LD WEP +L L LGN N ++E L +K P +P + KE YI AKYVE+ V + + S ++ I ++ + Q L V+ + ++D+ I + D V +DS H Q + K + A + +N N Q L+ A G+LV E L+Q GA++N RD GR PLHH + L+RGA D G L A+E
Sbjct: 11 LKDSPRFRAALEEVEGDVAELELKLDKLVKLCIAMIDTGKAFCVANKQFMNGIRDLAQYSSNDAVVETS---LTKFSDSLQEMINFHTILFDQTQRSIKAQLQNFVKEDLRKFKDAKKQFEKVSEEKENALVKNAQVQRNKQHE-VEEAANILTATRKCFRHIALDYVLQINVLQSKRRSEILKSMLSFMYAHLAFFHQGYDLFSELGPYMKDL--GAQLDRLVVDAAKEKREME-QKHSTIQQKDFSSDDSKLEYNVDAANGI-------------------------VMEGYLFKRASNAFKTWNRRWFSIQNNQLVYQKKFK-------------------------------------DSPTVVVEDLRLCTVK-HCEDIERRFCFEVVSPTKSCMLQADSEKLRQAWIKAVQTSIATAY--------REKGDESEKLDKKSSPSTGSLDS--GNESKEKLLKGESALQRVQCIPGNTSCCDCGLADPRWASINLGITLCIECSGIHRSLGVHFSKVRSLTLD--TWEPELLKLMCELGNDVINRVYEAKL-------EKMGVKKP---QPGQR---QEKEAYIRAKYVERKFVDKYSALLSPSEQEKRIISKSCEDQRLSHARASVHTPVKSNDSGIQQCSEDGRESLPSTVSANSLYEPEGERQESSVFLDSKHLNPGLQLYRASYEKNLPKMAEALAHGADVNWANSDEN--QATPLIQ-AVLGGSLVTCEFLLQNGANVNQRDVQGRGPLHHATVLGHTGQVCLFLKRGANQHATDEEGKDPLSIAVE 708
BLAST of hap2-g23221.t1 vs. ExPASy Swiss-Prot (2024) Match: sp|Q6IVG4|ACAP2_RABIT (Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2 OS=Oryctolagus cuniculus OX=9986 GN=ACAP2 PE=2 SV=1)
Query: 7 LEDSPMFQKQLFSMEESAEELKDRCQRLYKGCKKFTEALGVACSGDSAFADALEAFGGGHDDPVSVSIGGPVISKFINAFRELATYKELLRSQVEHVLINRLTEFLTVDLHDAKESRRRFDKSIHAYDQAREKFVSLKKNTRDDIVAELEEDLQNSKSAFEKSRFNLVSALTNIEAKKKYEFLESISAIMDVHLRYFKLGFDLLSKIEPYVHQVLTYAQQSKEVANVEQDKLAKRIQEFRTQAELDNLGVPVDVEHSV-SADGIHVGGTVSYKNIEAVMRSSATGEVQTIKQGYLLKRSSNLRGDWKRRFFVLNSQGTLYYYRNKGIKSMGSHHHYAGSADHNGGVFSRFRSRHYRSSSFNEDSLNCRTVDLRTSAIKMDAEDTDLRLCFRIISPVKTYTLQAETEADRMDWTSKITGVIASLLNSDFLQQLRPSAKHIDGNDPFSTRDIPSLSSHCSLEDEVKANKSDSVSAILRQIPGNDLCAECSAPDPDWASLNLGILLCIECSGVHRNLGVHISKVRSLKLDVKVWEPTILDLFGSLGNAYCNSIWEGLLLLKDREVDKSNTTIPSVRKPCSKDVFHYKEQYIHAKYV-----------------EKLLVIRDTSDAK----------SRTTSIWEAVKTQN--LQEVY-----RLIVTSDANII----NTTFDDVVGVDSYHRVDNTQYSEIDFHKVKKEENNGPAGCQRIKDSNDPGNCLQGGSLLHLACQCGNLVMLELLIQFGADINMRDFHGRTPLHHCISSKNFTFAKFLLRRGARPSIKDGGGLSSLERAME 771
L+DSP F+ L +E EL+ + +L K C + C + F + + + V ++KF ++ +E+ + +L Q + + +L F+ DL K+++++F+K + A K +++N + + V E L ++ F + V + +++K++ E L+S+ + M HL +F G+DL S++ PY+ + AQ + V + ++K Q+ T + D +E++V +A+GI + +GYL KR+SN W RR+F + + +Y + K D+ DLR +K ED + R CF ++SP K+ LQA++E R W + IA+ R + D S+ SL S E + K K +S ++ +PGN C +C DP WAS+NLGI LCIECSG+HR+LGVH SKVRSL LD WEP +L L LGN N ++E +N ++KP KE YI AKYV EK +V +D+ + + TSI +VK+ + +Q+ L T AN + D V +DS H Q + K + A + +N N + L A G+LV E L+Q GA++N RD GR PLHH + L+RGA D G L A+E
Sbjct: 11 LKDSPRFRAALEEVEGDVAELELKLDKLVKLCIAMIDTGKAFCLANKQFMNGIRDLAQYSSNDAVVETS---LTKFSDSLQEMINFHTILFDQTQRSIKAQLQNFVKEDLRKFKDAKKQFEKVSEEKENALAKNAQVQRNKQHE-VEEATNILTATRKCFRHIALDYVLQINVLQSKRRSEILKSMLSFMYAHLAFFHQGYDLFSELGPYMKDL--GAQLDRLVVDAAKEKREME-QKHSTIQQKDFSSDDSKLEYNVDAANGI-------------------------VMEGYLFKRASNAFKTWNRRWFSIQNNQLVYQKKFK-------------------------------------DNPTVVVEDLRLCTVK-HCEDIERRFCFEVVSPTKSCMLQADSEKLRQAWIKAVQTSIATAY--------REKGDESEKLDKKSSPSTGSLDS--GNESKEKLLKGESALQRVQCVPGNASCCDCGLADPRWASINLGITLCIECSGIHRSLGVHFSKVRSLTLD--TWEPELLKLMCELGNDVINRVYE------------ANVEKMGIKKP-QPGQRQEKEAYIKAKYVERKFVDKYSVSSSPPEQEKKVVSKDSEEKRLSIPKLGPGDQVRTSIQSSVKSNDSGIQQSSDDGRESLPSTVSANSLYEPEGERQDSSVFLDSKHLNPGLQLYRASYEKNLPKMAEALAHGADVNWANSEEN---KATPLIQAVLGGSLVTCEFLLQNGANVNQRDVQGRGPLHHATVLGHTGQVCLFLKRGANQHATDEEGKDPLSIAVE 716
BLAST of hap2-g23221.t1 vs. ExPASy Swiss-Prot (2024) Match: sp|Q5ZK62|ACAP2_CHICK (Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2 OS=Gallus gallus OX=9031 GN=ACAP2 PE=2 SV=1)
Query: 7 LEDSPMFQKQLFSMEESAEELKDRCQRLYKGCKKFTEALGVACSGDSAFADALEAFGGGHDDPVSVSIGGPVISKFINAFRELATYKELLRSQVEHVLINRLTEFLTVDLHDAKESRRRFDKSIHAYDQAREKFVSLKKNTRDDIVAELEEDLQNSKSAFEKSRFNLVSALTNIEAKKKYEFLESISAIMDVHLRYFKLGFDLLSKIEPYVHQVLTYAQQSKEVANVEQDKLAKRIQEFRTQAELDNLGVPVDVEHSV-SADGIHVGGTVSYKNIEAVMRSSATGEVQTIKQGYLLKRSSNLRGDWKRRFFVLNSQGTLYYYRNKGIKSMGSHHHYAGSADHNGGVFSRFRSRHYRSSSFNEDSLNCRTVDLRTSAIKMDAEDTDLRLCFRIISPVKTYTLQAETEADRMDWTSKITGVIASLLNSDFLQQLRPSAKHIDGNDPFSTRDIPSLSSHCSLEDEVKANKSDSVSAILRQIPGNDLCAECSAPDPDWASLNLGILLCIECSGVHRNLGVHISKVRSLKLDVKVWEPTILDLFGSLGNAYCNSIWEGLLLLKDREVDKSNTTIPSVRKPCSKDVFHYKEQYIHAKYVEKLLVIRDTSDA----KSRTTSIWEAV--KTQNLQEVYRLIVTSDANIINTTFDDVVGVDSYHRVDNTQ---YSEIDFHKVKKEENNGPAGCQRIKDSNDPGNCLQGGSLLHLACQCGNLVMLELLIQFGADINMRDF--HGRTPLHHCISSKNFTFAKFLLRRGARPSIKDGGGLSSLERAMEMGAITDEELFI 782
L+DSP F+ L +E EL+ + +L K C + C + F + + V ++KF + +E+ Y +L Q + + +L F+ D+ K+++++F+K + A K +++N + + V E L ++ F + V + +++K++ E L+S+ + M HL +F G+DL S++ PY+ + Q A E+ + Q+ T + D G +E++V +A+GI + +GYL KR+SN W RR+F + + +Y + K D+ DLR +K ED + R CF ++SP K+ LQA++E R W + IA+ + ++ S K + P ST + S S E + K K +S ++ IPGN C +C DP WAS+NLGI LCIECSG+HR+LGVH SKVRSL LD WEP +L L LGN N I+E L V+KP KE YI AKYVE+ V + + A +SRT + ++ K + E L + A D G+ VD+++ S I + + + P G ++ L G L+ A NL + + GA++N + + TPL + + +FLL+ GA +I+D G L A +G LF+
Sbjct: 11 LKDSPRFRAALEEVEGDVAELELKLDKLVKLCIAMIDTGKAFCLANKQFMNGIRDLAQYSCKDALVETN---LTKFSDTLQEMINYHNILFDQTQRSIKAQLQTFVKEDIKKFKDAKKQFEKVSEEKENALVKNAQVQRNKQHE-VEEATNILTATRKCFRHIALDYVLQINVLQSKRRSEILKSMLSFMYAHLTFFHQGYDLFSELGPYMKDLGAQLDQLAVDAAKEKRDME---QKHSTIQQKDYSGDDTKLEYNVDAANGI-------------------------VMEGYLFKRASNAFKTWNRRWFSIQNNQLVYQKKFK-------------------------------------DNPTVVVEDLRLCTVK-HCEDIERRFCFEVVSPTKSCMLQADSEKLRQAWIKAVQTSIATA----YREKGDESEKQEKKSSP-STGSLESGS-----ETKEKLLKGESALQRVQCIPGNAACCDCGLADPRWASINLGITLCIECSGIHRSLGVHFSKVRSLTLD--SWEPELLKLMCELGNDVINRIYEAKL------------EKMGVKKPQPGSQRQEKEMYIKAKYVERKFVEKQPAAAVSPLESRTKVLPQSQEEKRHSAPEKSFLAIEQGAASPRVRSSD-SGIQ--QSVDDSREHLASTISANSLYE-----PEGEKQESSVFYDSRQLNPGLHLYRAAFEKNLPDMAEALAHGAEVNWVNMEENKATPLIQAVRGGSLVTCEFLLQNGANVNIRDMKGRGPLHHATVLGHTGQVCLFL 696
BLAST of hap2-g23221.t1 vs. ExPASy Swiss-Prot (2024) Match: sp|Q96P50|ACAP3_HUMAN (Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 3 OS=Homo sapiens OX=9606 GN=ACAP3 PE=1 SV=2)
Query: 7 LEDSPMFQKQLFSMEESAEELKDRCQRLYKGCKKFTEALGVACSGDSAFADALEAFGGGHDDPVSVSIGGPVIS----KFINAFRELATYKELLRSQVEHVLINRLTEFLTVDLHDAKESRRRFDKSIHAYDQAREKF-VSLKKNT-----RDDIVAELEEDLQNSKSAFEKSRFNLVSALTNIEAKKKYEFLESISAIMDVHLRYFKLGFDLLSKIEPYVHQVLTYAQQSKEVANVEQDKLAKRIQEFRTQAELDNLGVPVDVEHSVSADGIHVGGTVSYKNIEAVMRSSATGEVQTIKQGYLLKRSSNLRGDWKRRFFVLNSQGTLYYYRNKGIKSMGSHHHYAGSADHNGGVFSRFRSRHYRSSSFNEDSLNCRTVDLRTSAIKMDAEDTDLRLCFRIISPVKTYTLQAETEADRMDWTSKITGVIASLLNSDFLQQLRPSAKHIDGNDPFSTRDIPSLSSHCSLED-EVKANKSDSVSAILRQIPGNDLCAECSAPDPDWASLNLGILLCIECSGVHRNLGVHISKVRSLKLDVKVWEPTILDLFGSLGNAYCNSIWEGLLLLKDREVDKSNTTIPSVRKPCSKDVFHYKEQYIHAKYVEK 600
++DSP F+ + +E E++ + +L K C EA A+ F G D G VIS +F ++ +E+ Y +L Q + + +L F+ D+ KE++++FDK RE +SL +N R V E L ++ F + V + ++AKKK+E L+S+ + M +F+ G+ LL +++PY+ ++ Q + VE+ ++ ++ + + L + SY + A V + +GYL KR+SN W RR+F + + +Y + K D+L DLR ++K ED + R CF ++SP K+ LQA++E R W + IAS P + + + D ++ PS SS S D + K +SV ++ + GN C +C PDP WAS+NLG+LLCIECSG+HR+LGVH SKVRSL LD WEP +L L LGN+ N I+E + + + + RKP + KE +I KYVEK
Sbjct: 9 VKDSPRFRATIDEVETDVVEIEAKLDKLVKLCSGMVEA-------GKAYVSTSRLFVSGVRDLSQQCQGDTVISECLQRFADSLQEVVNYHMILFDQAQRSVRQQLQSFVKEDVRKFKETKKQFDK-------VREDLELSLVRNAQAPRHRPHEVEEATGALTLTRKCFRHLALDYVLQINVLQAKKKFEILDSMLSFMHAQSSFFQQGYSLLHQLDPYMKKLAAELDQLVIDSAVEKREMERKHAAIQQRTLLQDF---------------------SYDESKVEFDVDAPSGV--VMEGYLFKRASNAFKTWNRRWFSIQNSQLVYQKKLK-------------------------------------DALTVVVDDLRLCSVK-PCEDIERRFCFEVLSPTKSCMLQADSEKLRQAWVQAVQASIASAYRES------PDSCYSERLDRTAS---PSTSSIDSATDTRERGVKGESVLQRVQSVAGNSQCGDCGQPDPRWASINLGVLLCIECSGIHRSLGVHCSKVRSLTLD--SWEPELLKLMCELGNSAVNQIYEA-------QCEGAGS-----RKPTASSSRQDKEAWIKDKYVEK 515
BLAST of hap2-g23221.t1 vs. ExPASy Swiss-Prot (2024) Match: sp|Q15057|ACAP2_HUMAN (Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2 OS=Homo sapiens OX=9606 GN=ACAP2 PE=1 SV=3)
Query: 7 LEDSPMFQKQLFSMEESAEELKDRCQRLYKGCKKFTEALGVACSGDSAFADALEAFGGGHDDPVSVSIGGPVISKFINAFRELATYKELLRSQVEHVLINRLTEFLTVDLHDAKESRRRFDKSIHAYDQAREKFVSLKKNTRDDIVAELEEDLQNSKSAFEKSRFNLVSALTNIEAKKKYEFLESISAIMDVHLRYFKLGFDLLSKIEPYVHQVLTYAQQSKEVANVEQDKLAKRIQEFRTQAELDNLGVPVDVEHSV-SADGIHVGGTVSYKNIEAVMRSSATGEVQTIKQGYLLKRSSNLRGDWKRRFFVLNSQGTLYYYRNKGIKSMGSHHHYAGSADHNGGVFSRFRSRHYRSSSFNEDSLNCRTVDLRTSAIKMDAEDTDLRLCFRIISPVKTYTLQAETEADRMDWTSKITGVIASLLNSDFLQQLRPSAKHIDGNDPFSTRDIPSLSSHCSLEDEVKANKSDSVSAILRQIPGNDLCAECSAPDPDWASLNLGILLCIECSGVHRNLGVHISKVRSLKLDVKVWEPTILDLFGSLGNAYCNSIWEGLLLLKDREVDKSNTTIPSVRKPCSKDVFHYKEQYIHAKYVEKLLV 603
L+DSP F+ L +E EL+ + +L K C + C + F + + + V ++KF ++ +E+ + +L Q + + +L F+ DL K+++++F+K + A K +++N + + V E L ++ F + V + +++K++ E L+S+ + M HL +F G+DL S++ PY+ + AQ + V + ++K Q+ T + D +E++V +A+GI + +GYL KR+SN W RR+F + + +Y + K D+ DLR +K ED + R CF ++SP K+ LQA++E R W + IA+ R + D S+ SL S E + K K +S ++ IPGN C +C DP WAS+NLGI LCIECSG+HR+LGVH SKVRSL LD WEP +L L LGN N ++E +N ++KP KE YI AKYVE+ V
Sbjct: 11 LKDSPRFRAALEEVEGDVAELELKLDKLVKLCIAMIDTGKAFCVANKQFMNGIRDLAQYSSNDAVVETS---LTKFSDSLQEMINFHTILFDQTQRSIKAQLQNFVKEDLRKFKDAKKQFEKVSEEKENALVKNAQVQRNKQHE-VEEATNILTATRKCFRHIALDYVLQINVLQSKRRSEILKSMLSFMYAHLAFFHQGYDLFSELGPYMKDL--GAQLDRLVVDAAKEKREME-QKHSTIQQKDFSSDDSKLEYNVDAANGI-------------------------VMEGYLFKRASNAFKTWNRRWFSIQNNQLVYQKKFK-------------------------------------DNPTVVVEDLRLCTVK-HCEDIERRFCFEVVSPTKSCMLQADSEKLRQAWIKAVQTSIATAY--------REKGDESEKLDKKSSPSTGSLDS--GNESKEKLLKGESALQRVQCIPGNASCCDCGLADPRWASINLGITLCIECSGIHRSLGVHFSKVRSLTLD--TWEPELLKLMCELGNDVINRVYE------------ANVEKMGIKKP-QPGQRQEKEAYIRAKYVERKFV 513
The following BLAST results are available for this feature:
